Anna Santoro | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

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Dr. Anna Santoro | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

Beth Israel Deaconess Medical Center | United States

Dr. Anna Santoro’s research profile reflects a strong and sustained contribution to biomedical and toxicological sciences, with a particular focus on inflammatory pathways, metabolic regulation, environmental toxicants, and neuroendocrine mechanisms. Her scholarly output comprises 28 peer-reviewed documents, which together have received 1,584 citations across 1,472 citing documents, demonstrating broad international impact and cross-disciplinary relevance. With an h-index of 22, her work shows both productivity and consistent citation performance. Key investigations explore the biological effects of non-dioxin-like polychlorinated biphenyls on cellular apoptosis, lipid metabolism, and endocrine signaling, alongside influential studies on palmitoylethanolamide and its protective roles in metabolic disorders, hypertension, renal injury, and neuroinflammation. Her publications in high-impact journals such as Toxicology Letters, Endocrinology, PLoS One, and Journal of Nutritional Biochemistry highlight rigorous experimental approaches and translational relevance, positioning her research as a significant reference point in toxicology, pharmacology, and metabolic disease research.

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Featured Publications

Judith Röske | Biochemistry, Genetics and Molecular Biology | Women Research Award

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Mrs. Judith Röske | Biochemistry, Genetics and Molecular Biology | Women Research Award

University of Luebeck | Germany

Mrs. Judith Röske is a dedicated researcher with a strong focus on molecular virology, antiviral drug discovery, and protease-targeted therapeutic development, contributing to 13 scientific publications across high-impact journals. Her work explores the binding behavior of small-molecule inhibitors to viral 3C proteases, including SARS-CoV-2, EV-D68, EV-A71, and HAV, as well as host proteases such as cathepsins and calpain-1. With expertise in photometry, nanoDSF, MST, and SPR, she has optimized methods for determining key biochemical parameters such as IC₅₀, Tm, and Kᴅ, enabling the effective screening of lead compounds for broad-spectrum antivirals. Her research further investigates RNA-binding mechanisms in HAV 3C protease, shedding light on dual-targeting strategies that may advance anti-picornaviral drug development. She has contributed to influential studies on SARS-CoV-2 main protease inhibitors, including work on novel warhead chemistries, α-ketoamide derivatives, and diastereomeric optimization, reinforcing her impact in antiviral medicinal chemistry. Additionally, earlier contributions in transplant biology and liver preservation highlight her versatility in biochemical and molecular research. Through rigorous structural, kinetic, and biophysical analyses, her body of work adds valuable insight into protease inhibition and therapeutic innovation, supported by a growing citation record within the scientific community.

Profiles : Scopus | Orcid

Featured Publications

Theodoropoulou, M. A., El Kilani, H., Mantzourani, C., Jochmans, D., Neyts, J., Zhang, K., Röske, J., Kokotou, M. G., Hilgenfeld, R., & Kokotos, G. (2025). Thiazolyl 4-carboxylate ketone as a new warhead for a highly potent SARS-CoV-2 main protease inhibitor. European Journal of Medicinal Chemistry, 25(11), 118436.

Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., et al. (2025). Structure-based optimization of pyridone α-ketoamides as inhibitors of the SARS-CoV-2 main protease. Journal of Medicinal Chemistry, 68(1).

Cooper, M. S., Zhang, L., Ibrahim, M., Zhang, K., Sun, X., Röske, J., Göhl, M., Brönstrup, M., Cowell, J. K., Sauerhering, L., et al. (2022). Diastereomeric resolution yields highly potent inhibitor of SARS-CoV-2 main protease. Journal of Medicinal Chemistry.

Bernard, V., Gebauer, N., Dinh, T., Stegemann, J., Feller, A. C., & Merz, H. (2014). Applicability of next-generation sequencing to decalcified formalin-fixed and paraffin-embedded chronic myelomonocytic leukaemia samples. International Journal of Clinical and Experimental Pathology.

Le Minh, K., Berger, A., Eipel, C., Kuhla, A., Minor, T., Stegemann, J., & Vollmar, B. (2011). Uncoupling protein-2 deficient mice are not protected against warm ischemia/reperfusion injury of the liver. Journal of Surgical Research, 167.

Stegemann, J., Hirner, A., Rauen, U., & Minor, T. (2010). Use of a new modified HTK solution for machine preservation of marginal liver grafts. Journal of Surgical Research.

Koetting, M., Stegemann, J., & Minor, T. (2010). Dopamine as additive to cold preservation solution improves postischemic integrity of the liver. Transplant International, 23.

Minor, T., Stegemann, J., Hirner, A., & Koetting, M. (2009). Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning. Liver Transplantation.

Stegemann, J., & Minor, T. (2009). Energy charge restoration, mitochondrial protection and reversal of preservation-induced liver injury by hypothermic oxygenation prior to reperfusion. Cryobiology.

Stegemann, J., Hirner, A., Rauen, U., & Minor, T. (2009). Gaseous oxygen persufflation or oxygenated machine perfusion with Custodiol-N for long-term preservation of ischemic rat livers? Cryobiology.

Le Minh, K., Kuhla, A., Abshagen, K., Minor, T., Stegemann, J., Ibrahim, S., Eipel, C., & Vollmar, B. (2009). Uncoupling protein-2 deficiency provides protection in a murine model of endotoxemic acute liver failure. Critical Care Medicine.

Manekeller, S., Seinsche, A., Stegemann, J., & Hirner, A. (2008). Optimising post-conditioning time of marginal donor livers. Langenbeck's Archives of Surgery.

Manekeller, S., Schuppius, A., Stegemann, J., Hirner, A., & Minor, T. (2007). Role of perfusion medium, oxygen and rheology for endoplasmic reticulum stress-induced cell death after hypothermic machine preservation of the liver. Transplant International.

Giovanni Smaldone | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Dr. Giovanni Smaldone | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

IRCCS Synlab SDN | Italy

Dr. Giovanni Smaldone is a highly accomplished researcher whose work spans molecular biology, structural biochemistry, oncology, immunology, and advanced diagnostic technologies. With 1,037 citations, 83 published works, and an h-index of 18, his contributions reflect both productivity and strong scientific impact. His research integrates structural biology, NMR spectroscopy, molecular interactions, and translational oncology, with a particular emphasis on childhood acute lymphoblastic leukemia (ALL). He has led and contributed to numerous funded research projects, including competitive grants focused on long non-coding RNAs, epigenetic markers, and the KCTD protein family in pediatric leukemia. His studies also extend into protein delivery systems, nanogels, cellular imaging, and biobank development for rare pediatric disorders. Dr. Smaldone’s recent publications highlight advancements in 3D refractive index tomography for leukemia cell analysis, targeted drug-delivery platforms, diagnostic biomarkers such as circular RNAs and LINC00958, and the structural mechanisms underlying KCTD–Cullin 3 interactions. His work frequently appears in high-impact journals across molecular sciences, biomedical engineering, nanotechnology, and clinical research. Additionally, he has presented widely at national and international scientific conferences, contributing to knowledge dissemination in cellular biophysics, protein structure, pediatric oncology, and advanced molecular diagnostics.

Profiles : Scopus | Orcid

Featured Publications

Bianco, V., Pirone, D., Schiavo, M., Bianco, V., Miccio, L., Memmolo, P., Smaldone, G., Pecoraro, G., Altieri, F., Salvatore, M., et al. (2026). Quantitative mapping of leukemia cells and intracellular lipid droplets using 3D refractive index tomography in flow cytometry. IEEE Journal of Selected Topics in Quantum Electronics.

Pizzella, M., Accardo, A., Mercurio, F. A., Sibillano, T., Gallo, E., Morelli, G., Smaldone, G., Giannini, C., Leone, M., Balasco, N., et al. (2025). Structural and functional characterization of self-assembling fragments identified from the transthyretin amyloid-like structure. Nanoscale.

Leone, I., Costabile, V., Smaldone, G., Franzese, M., Soricelli, A., & D’Agostino, A. (2025). Arthrospira platensis attenuates endothelial inflammation and monocyte activation. International Journal of Molecular Sciences.

Gallo, E., Smaldone, G., Cimmino, L., Braile, M., Orlandella, F. M., Luciano, N., Accardo, A., & Salvatore, G. (2025). Fmoc-FF nanogel-mediated delivery of doxorubicin and curcumin in thyroid cancer cells. Pharmaceutics.

Balasco, N., Esposito, L., Smaldone, G., Salvatore, M., & Vitagliano, L. (2024). A comprehensive analysis of the structural recognition between KCTD proteins and Cullin 3. International Journal of Molecular Sciences.

Bianco, V., Wang, Z., Brancato, V., Coppola, L., Smaldone, G., D’Aiuto, M., Mossetti, G., Maffettone, P. L., Salvatore, M., & Ferraro, P. (2024). Adaptive space-time digital holography for imaging flow cytometry and tissue slide analysis. In Digital Holography and Three-Dimensional Imaging (DH 2024).

Coppola, L., Grimaldi, A. M., Sarnacchiaro, G., Di Fasano, M. S., Smaldone, G., & Salvatore, M. (2024). An overview of Synlab SDN Biobank’s quality control system. Scientific Reports.

De Martino, L., Mirabelli, P., Quaglietta, L., Ferrara, U. P., Picariello, S., De Gennaro, D. V., Aiello, M., Smaldone, G., Aliberti, F., Spennato, P., et al. (2024). Biobank for craniosynostosis and faciocraniosynostosis: A study protocol. Child’s Nervous System.

Bianco, V., Valentino, M., Pirone, D., Miccio, L., Memmolo, P., Brancato, V., Coppola, L., Smaldone, G., D’Aiuto, M., & Mossetti, G. (2024). Classifying breast cancer and fibroadenoma tissue biopsies using fractal biomarkers in Fourier ptychographic microscopy. Computational and Structural Biotechnology Journal.

De Martino, L., Mirabelli, P., Quaglietta, L., Ferrara, U. P., Picariello, S., De Gennaro, D. V., Aiello, M., Smaldone, G., Aliberti, F., Spennato, P., et al. (2024). Correction: Biobank for craniosynostosis and faciocraniosynostosis. Child’s Nervous System.

Gallo, E., Diaferia, C., Smaldone, G., Rosa, E., Pecoraro, G., Morelli, G., & Accardo, A. (2024). Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells. Scientific Reports.

Gallo, E., Diaferia, C., Smaldone, G., Rosa, E., Pecoraro, G., Morelli, G., & Accardo, A. (2024). Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells. Research Square.

Filomena, A., Smaldone, G., Ginevra, S., Santiago, N., Di Fasano, M. S., Peppino, M., Alessandra, C., Antonia, D. M., Giuliana, B., Rosanna, P., et al. (2024). Identification of a circular RNA isoform of WASHC2A as a prognostic factor for high-risk pediatric B-ALL. Biomedicine & Pharmacotherapy.

Raymundo, J. R., Zhang, H., Smaldone, G., Zhu, W., Daly, K. E., Glennon, B. J., Pecoraro, G., Salvatore, M., Devine, W. A., Lo, C. W., et al. (2024). KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions. Journal of Clinical Investigation.

Altieri, F., Buono, L., Lanzilli, M., Mirabelli, P., Cianflone, A., Beneduce, G., De Matteo, A., Parasole, R., Salvatore, M., & Smaldone, G. (2024). LINC00958 as a diagnostic and prognostic biomarker of childhood B-cell acute lymphoblastic leukemia. Frontiers in Oncology.

Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

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Prof. Dr. Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Soonchunhyang University | South Korea

Prof. Dr. Keon-Hyoung Song is a distinguished researcher whose work bridges pharmaceutical sciences, drug delivery systems, and pharmacokinetics. With 708 citations, 27 scholarly publications, and an h-index of 13, his research has significantly advanced the understanding of membrane permeation enhancers, drug formulation, and solubilization strategies. His extensive portfolio includes high-impact studies on intestinal absorption mechanisms, cocrystal engineering, and pharmacokinetic optimization, published in reputed journals such as Pharmaceutics, European Journal of Medicinal Chemistry, and Journal of Controlled Release. Prof. Song’s innovations extend beyond academia, with over 25 international patents registered across the U.S., Europe, and Korea, focusing on permeation-enhancing peptides, liposomal carriers, and pharmaceutical formulations. His pioneering patents, including those on mucous membrane permeation peptides (EP 3875103, 2025) and sugar alcohol-based liposome compositions, underscore his role in translating laboratory discoveries into therapeutic applications. Licensed as both a Patent Attorney and a Pharmacist, he effectively integrates regulatory insight with scientific innovation. Prof. Song’s sustained contributions to quantitative drug analysis using LC-MS and formulation optimization have made him a leading figure in advancing next-generation drug delivery technologies and pharmaceutical development.

Profile : Scopus

Featured Publications

Jeong, D.-H., Kim, J.-W., & Song, K.-H. (2025). Improved intestinal permeation of cyclosporin A by FCIGRL-modified tight junction modulator in rats. Pharmaceutics, 17(11), 1395.

Park, G., Galdamez, A., Song, K.-H., Le, M., Kim, K., & Lin, J. H. (2024). Ethnic variation and structure–function analysis of tauopathy-associated PERK alleles. Israel Journal of Chemistry, 64(12).

Song, K.-H. (2024). Effect of tight junction-modulating FCIGRL-modified peptides on the intestinal absorption of doxorubicin in rats. Pharmaceutics, 16(5), 650.

Jiang, F.-L., Jeong, D.-H., Eom, S.-H., Lee, H.-M., Cha, B.-J., Park, J.-S., Kwon, R.-K., Nam, J.-Y., Yu, H.-S., Heo, S.-H., Kim, C.-H., & Song, K.-H. (2024). Effects of enteric-coated formulation of sodium bicarbonate on bicarbonate absorption and gastrointestinal discomfort. Nutrients, 16(5), 744.

Koo, N. R., Yoon, S., Song, K.-H., Baek, M. J., Jeon, S., & Im, J. (2024). Tumor-homing peptide iRGD-conjugate enhances tumor accumulation of camptothecin for colon cancer therapy. European Journal of Medicinal Chemistry, 265, 116050.

Park, G., Xu, K., Chea, L., Kim, K., Safarta, L., Song, K.-H., Wu, J., Park, S., Min, H., Hiramatsu, N., Han, J., & Lin, J. H. (2023). Neurodegeneration risk factor EIF2AK3 (PERK) influences tau protein aggregation. The Journal of Biological Chemistry, 299(2), 102821.

Eom, Y. S., Jeong, D., Ryu, A.-R., Song, K.-H., Im, D. S., & Lee, M.-Y. (2022). Daphne odora exerts depigmenting effects via inhibiting CREB/MITF and activating AKT/ERK-signaling pathways. Current Issues in Molecular Biology, 44(8), 3312–3323.

Kim, H., Song, K.-H., Ambegaonkar, J. P., Chung, S., Jeon, K., Jiang, F. L., Eom, J. J., & Kim, C.-H. (2022). Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people. BMC Geriatrics, 22(1), 385.

Jiang, F., Tang, S., Eom, J.-J., Song, K.-H., Kim, H., Chung, S., & Kim, C.-H. (2022). Accuracy of estimated bioimpedance parameters with octapolar segmental bioimpedance analysis. Sensors, 22(7), 2681.

Yoon, Y. M., Lee, J. H., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins. Journal of Pineal Research, 68(3), e12632.

Lee, J. H., Yoon, Y. M., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. Aging Cell, 19(3), e13111.

Cha, S. J., Choi, H.-J., Kim, H.-J., Choi, E. J., Song, K.-H., Im, D. S., & Kim, K. (2020). Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. Insect Molecular Biology, 29(1), 56–65.*

Anita Kavrakova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Mrs. Anita Kavrakova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Genetic Medico-Diagnostic Laboratory “Genica” | Bulgaria

Mrs. Anita Kavrakova is a distinguished molecular biologist and project manager with extensive experience in medical genetics and diagnostic research. Since 2019, she has been serving as Project Manager at Genetic Medico-Diagnostic Laboratory “Genica” and Genome Center Bulgaria AD in Sofia, where she oversees laboratory projects, implements innovative diagnostic techniques, ensures compliance with national and international standards, and actively contributes to scientific research through conferences, publications, and collaborative studies. Prior to this role, she worked as a Molecular Biologist at Genica (2008–2018), conducting advanced molecular analyses including PCR, qPCR, gene sequencing, and immunohistochemistry, with a focus on cancer genetics, particularly prostate and cervical cancers. She has also been a part-time assistant at the Department of Medical Chemistry and Biochemistry, Medical University Sofia, since 2012, training students in theoretical and practical biochemistry. Dr. Kavrakova earned her PhD in Genetics from Medical University Sofia in 2015, investigating molecular markers in prostate cancer for improved diagnostics and patient management, following an MS in Genetics and a Bachelor in Biology from Sofia University “St Kliment Ohridski.” She has contributed to numerous national and international research projects on infectious agents, reproductive failure, and cancer etiology, authored multiple publications, and actively participates in innovation evaluation and scientific advisory roles, demonstrating leadership, analytical skills, and a commitment to advancing molecular diagnostics and biomedical research.

Profiles : Scopus | Orcid

Featured Publications

Todorova, E., Kavrakova, A., Derimachkovski, G., Georgieva, B., Odzhakov, F., Bachurska, S., Terziev, I., Boyadzhieva, M. E., Valkov, T., Popov, E., Slavov, C., Tourtourikov, I., Mitev, V., & Todorova, A. (2025). Human Herpes Virus genotype and immunological gene expression profile in prostate cancer with prominent inflammation. International Journal of Molecular Sciences, 26(10), 4945.

Todorova, E., & Kavrakova, A., Derimachkovski, G., Georgieva, B., Kalenderova, S., Odzhakov, F., Bachurska, S., Boyadzhieva, M. E., Terziev, I., Genova, M., Mitev, V., & Todorova, A. (2025). Pathogenic contribution of human papillomaviruses and Epstein-Barr virus to prostate cancer in Bulgarian patients. C. R. Acad. Bulg. Sci. (submitted).

Mesechkova, K., Kavrakova, A., Georgieva, B., Sigridov, I., Miteva, A., Mitev, V., & Todorova, A. (2023). Bacterial and viral pathogens implicated in female reproductive failure investigated on menstrual blood. C. R. Acad. Bulg. Sci., 76(3), 394–406.

Mesechkova, K., Kavrakova, A., Georgieva, B., Sigridov, I., Mitev, V., & Todorova, A. (2023). Non-invasive diagnostics of reproductive failure with infectious etiology on menstrual tissue. Acta Medica Bulgarica, 50(3).

Mesechkova, K., Kavrakova, A., Todorova, E., Georgieva, B., Sigridov, I., Mitev, V., & Todorova, A. (2023). Role of bacterial and viral infections and co-infections in miscarriages. Acta Medica Bulgarica, 50(4).

Kavrakova, A., Todorova, A., Georgieva, B., Anachkov, K., Yanev, K., Ivanov, G., & Mitev, V. (2018). Investigation of noninvasive urine specimens with molecular fluctuations for a presence of high-risk human papilloma viruses as an inflammatory cofactor in prostate cancer. Journal of Biology and Medicine.

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2015). Molecular and clinico-histological data in aggressive prostate cancer patients from Bulgaria. JBUON, 20(2).

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2015). Molecular and clinicopathological aspects of prostate cancer in Bulgarian probands. Journal of Pathology and Oncology Research.

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2014). Molecular profile and clinicopathological aspects of prostate cancer in Bulgarian patients. Journal of BOD, 4, 18–26.

Tsvetkova, A., Kadiyska, T., Georgiev, G., Drandarska, I., Todorova, A., & Mitev, V. (2013). Molecular-genetic approach in combination with clinical and histological data for diagnostics of prostate cancer. Journal of Oncology, 3, 50–55.

 

 

Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Mrs. Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Medical University-Plovdiv | Bulgaria

Mrs. Valentina Mihaylova is a dedicated researcher and specialist in medical chemistry with a strong focus on cellular metabolism, mitochondrial function, oxidative stress, and autoimmune diseases. With an h-index of 2, she has authored five scientific publications, which have collectively garnered 14 citations, reflecting her growing impact in medical biology and clinical research. Her work encompasses the study of markers of oxidative stress and insulin resistance in chronic autoimmune Hashimoto’s thyroiditis, cellular metabolic profiling in children with autism spectrum disorders, and the evaluation of therapeutic effects in rheumatoid arthritis through mitochondrial function and bioenergetic metabolism. Mrs. Mihaylova’s research also explores intestinal permeability, systemic inflammation, and the pharmacological effects of treatments such as methotrexate and JAK inhibitors on mitochondrial function and oxidative stress. She has actively contributed to numerous national and international conferences, presenting pioneering findings on the role of mitochondria, autophagy, and inflammation in autoimmune and rheumatologic conditions. Her academic and professional trajectory, spanning positions from clinical chemist to Master of Medical Chemistry at the Medical University of Plovdiv, is marked by a commitment to advancing knowledge in medical biology and translational research. Through her multidisciplinary approach, Mrs. Mihaylova continues to elucidate complex biochemical mechanisms underlying disease pathology and therapeutic responses, establishing herself as an emerging contributor to the field of medical and clinical biochemistry.

Profiles : Scopus | Orcid

Featured Publications

Mihaylova, V., Tomov, D., Karalilova, R., Batalov, Z., Batalov, A., Sarafian, V., & Kazakova, M. (2025). Effects of methotrexate and tofacitinib on mitochondrial function and oxidative stress in human synovial cells in vitro. International Journal of Molecular Sciences, 26(17), 8173.

Tomov, D. G., Levterova, B. A., Mihaylova, V. N., Troev, D. M., Miteva, M. Z., Uzunova, Y. I., & Orbetzova, M. M. (2024). Influence of the increase in intestinal permeability and microbiota change in the development of Hashimoto's thyroiditis: A systematic review. Endocrine and Metabolic Science, 100195.

Mihaylova, V., Kazakova, M., Batalov, Z., Karalilova, R., Batalov, A., & Sarafian, V. (2023). JAK inhibitors improve ATP production and mitochondrial function in rheumatoid arthritis: A pilot study. Rheumatology International.

Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Assist. Prof. Dr. Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Macau University Of Science And Technology | Macau

Assist. Prof. Dr. Panpan Hou is a distinguished researcher in the field of Biomedical Engineering and Biophysics, with a prolific record of 375 documents, 541 citations, and an h-index of 16. After obtaining a B.S. in Biomedical Engineering and a Ph.D. in Biophysics from Huazhong University of Science and Technology, Dr. Hou completed postdoctoral training at Washington University in St. Louis before joining Macau University of Science and Technology as an Assistant Professor in 2021. Dr. Hou’s research focuses on ion channel physiology, voltage-sensor domain (VSD) mechanisms, and electro-mechanical coupling, elucidating complex molecular processes such as the VSD-pore coupling in KCNQ1 channels and identifying novel modulators with therapeutic potential. He has made significant contributions to drug screening, cardiovascular disease modeling, and electrophysiology, publishing high-impact work in journals including Nature Communications, PNAS, eLife, Circulation Research, and Scientific Reports. Dr. Hou has received multiple awards including the AHA Postdoctoral Fellowship, Best Poster Awards at international symposia, and the 2025 Best Research Output Award from Macau University of Science and Technology. Beyond research, he actively mentors students, serves on editorial boards, and contributes to national and international scientific societies. With a strong track record of innovation, mentorship, and high-impact publications, Dr. Hou exemplifies excellence in biomedical research and is poised to advance the understanding of ion channel physiology and therapeutic interventions.

Profiles : Scopus | Orcid | Google Scholar

Featured Publications

Zhong, L., Lin, X., Cheng, X., Wan, S., Hua, Y., Nan, W., Hu, B., Peng, X., Zhou, Z., Zhang, Q., Yang, H., Noé, F., Yan, Z., Jiang, D., Zhang, H., Liu, F., Xiao, C., Zhou, Z., Mou, Y., Yu, H., Ma, L., Huang, C., Wong, V. K. W., Chung, S. K., Shen, B., Jiang, Z.-H., Neher, E., Zhu, W., Zhang, J., & Hou, P. (2025). Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating. Cell Research.

Hou, P., Zhao, L., Zhong, L., Shi, J., Wang, H. Z., Gao, J., Liu, H., Zuckerman, J., Cohen, I. S., & Cui, J. (2024). The fully activated open state of KCNQ1 controls the cardiac “fight-or-flight” response. PNAS Nexus.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2022). Author correction: A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Dou, A., Kang, P. W., Hou, P., Zaydman, M. A., Zheng, J., Jegla, T., & Cui, J. (2021). Principles of sensor-effector organization in six-transmembrane ion channels.

Lin, Y., Grinter, S. Z., Lu, Z., Xu, X., Wang, H. Z., Liang, H., Hou, P., Gao, J., Clausen, C., & Shi, J. (2021). Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. Proceedings of the National Academy of Sciences.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2020). A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Taylor, K. C., Kang, P. W., Hou, P., Yang, N.-D., Kuenze, G., Smith, J. A., Shi, J., Huang, H., McFarland White, K., & Peng, D. (2020). Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. eLife.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2020). Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation. Nature Communications.

Zhu, W., Mazzanti, A., Voelker, T. L., Hou, P., Moreno, J. D., Angsutararux, P., Naegle, K. M., Priori, S. G., & Silva, J. R. (2019). Predicting patient response to the antiarrhythmic mexiletine based on genetic variation: Personalized medicine for long QT syndrome. Circulation Research.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2019). Two-stage electro-mechanical coupling of a KV channel in voltage-dependent activation.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling. eLife.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances pore opening of KCNQ1 with VSD at the activated state by modulating VSD-pore coupling.

Hou, P., Eldstrom, J., Shi, J., Zhong, L., McFarland, K., Gao, Y., Fedida, D., & Cui, J. (2017). Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening. Nature Communications.

Xin Wang | Chemistry | Best Researcher Award

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Assoc. Prof. Dr. Xin Wang | Chemistry | Best Researcher Award

Zhengzhou University | China

Assoc. Prof. Dr. Xin Wang is an accomplished researcher in the field of chemistry and nanomaterials, with a strong focus on advanced energy storage and conversion systems. His research spans lithium-ion and lithium-sulfur batteries, metal-air batteries, supercapacitors, fuel cells, electrocatalysis, CO₂ reduction, and solar cells. Over the years, he has made significant contributions to the controllable synthesis of alloy-based nanomaterials, the development of high-entropy alloys, and the application of innovative catalysts for electrochemical CO₂ conversion and energy storage. His academic output is substantial, with 52 documents published, garnering 4,164 citations overall (3,400 since 2020), reflecting his consistent influence in the scientific community. He holds an h-index of 32 (30 since 2020) and an i10-index of 52, showcasing both the depth and breadth of his impactful work. His publications in high-impact journals, including Nature Communications, Journal of the American Chemical Society, Advanced Functional Materials, and Journal of Materials Chemistry A, underscore his role as a leading scientist in sustainable energy research. Recognized with multiple awards, fellowships, and competitive research grants, he continues to drive innovation in nanomaterials, electrocatalysis, and green energy technologies, shaping future directions in electrochemistry and materials science.

Profiles : Scopus | Orcid | Google Scholar

Featured Publications

Cai, M., Dong, Y., Xie, M., Dong, W., Dong, C., Dai, P., Zhang, H., Wang, X., Sun, X., Zhang, S., Yoon, M., Xu, H., Ge, Y., Li, J., & Huang, F. (2023). Stalling oxygen evolution in high-voltage cathodes by lanthurization. Nature Energy, 8(2), 159–168.

Fan, H., Si, Y., Zhang, Y., Zhu, F., Wang, X., & Fu, Y. (2024). Grapevine-like high entropy oxide composites boost high performance lithium sulfur batteries as bifunctional interlayers. Green Energy & Environment, 9(3), 565–572.

Wang, X., Miao, M., Tang, B., Duan, H., Zhu, F., Zhang, H., Zhang, X., Yin, W., & Fu, Y. (2023). Chlorine-induced mixed valence of CuOx/C to promote the electroreduction of carbon dioxide to ethylene. Nano Research, 16(20), 8827–8835.

Zhang, Y., Yu, Q., Wang, X., & Guo, W. (2023). Conversion of nitrogenous small molecules into value-added chemicals by building N–C bonds. Chemical Engineering Journal, 474, 145899.

Chai, D., Yan, H., Wang, X., Li, X., & Fu, Y. (2024). Retuning solvating ability of ether solvent by anion chemistry toward 4.5 V class Li metal battery. Advanced Functional Materials, 34(23), 2310516.

Yang, W., Xu, T., Fan, H., Yang, C., Sun, W., Ma, X., Wang, X., & Fu, Y. (2024). Selective and bifunctional catalytic electrochemical conversion of organosulfide molecule by high-entropy carbides. Advanced Functional Materials, 34(24), 2409450.

Wang, X., Li, W., Lv, X., & Broekmann, P. (2024). When chiral chemistry meets electrochemistry: A virgin land of an academic gold mine. Matter, 7(10), 2626–2788.

Cao, M., Li, W., Li, T., Zhu, F., & Wang, X. (2024). Polymetallic amorphous materials: Research progress in synthetic strategies and electrocatalytic applications. Journal of Materials Chemistry A, 12(30), 15541–15557.

Cui, T., Xu, J., Wang, X., Liu, L., Xiang, Y., Zhu, H., Li, X., & Fu, Y. (2024). Highly reversible transition metal migration in superstructure-free Li-rich oxide boosting voltage stability and redox symmetry. Nature Communications, 15, 4742.

Duan, H., Li, W., Ran, L., Zhu, F., Li, T., Miao, M., Yin, W., Wang, X., & Fu, Y. (2024). In-situ electrochemical interface of Cu@Ag/C towards the ethylene electrosynthesis with adequate *CO supply. Journal of Energy Chemistry, 99, 292–299.

Ma, X., Zhang, Y., Yang, W., Liu, C., Wang, X., & Fu, Y. (2025). Defect-engineered NbSx as an efficient cathode host for high-performance Li–organosulfur batteries. ChemSusChem. Advance online publication. e202500983.

Cao, M., Miao, H., Li, J., Liu, C., Wang, X., & Fu, Y. (2025). Tailoring the ionomer type to optimize catalyst microenvironment for enhanced CO2 reduction in membrane electrode assembly. Carbon Energy. Advance online publication.

Hemantkumar Akolkar | Chemistry | Best Researcher Award

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Assoc. Prof. Dr. Hemantkumar Akolkar | Chemistry | Best Researcher Award

Rayat Shikshan Sanstha’s Abasaheb Marathe Arts and New Commerce, Science College | India

Assoc. Prof. Dr. Hemantkumar Akolkar is a distinguished academic and researcher in the field of chemistry with over 15 years of teaching and research experience. He earned his Ph.D. in Chemistry from Radhabai Kale Mahila Mahavidyalaya, affiliated with Savitribai Phule Pune University, and has since contributed significantly to the advancement of heterocyclic and green chemistry. His prolific research career includes 66 publications in reputed international journals, with an h-index of 7, i10-index of 4, and 284 citations, reflecting the growing impact of his work. Dr. Akolkar has successfully completed funded research projects from UGC and BCUD and holds six granted Indian patents on novel heterocyclic compounds with therapeutic and industrial potential. He has authored seven books and nine book chapters with leading publishers such as Springer, IGI Global, and the Royal Society of Chemistry, further highlighting his academic contributions. Additionally, he has presented 17 research papers at national and international conferences, organized academic events, and serves as a reviewer for renowned international journals including Scientific Reports and ChemistrySelect. Recognized as a Ph.D. guide and PG teacher by multiple universities, his work bridges innovation, pedagogy, and research leadership, making him a highly respected figure in chemical sciences.

Profiles : Scopus | Orcid | Google Scholar

Featured Publications

"Eco-Friendly Fabrication of Silver Nanoparticles Using Syzygium stocksii Leaf Extract: Physicochemical Characterization and Evaluation of Antioxidant and Anti-Inflammatory Activities"

"Synthesis, Antimicrobial Activity, and Molecular Docking Study of Novel (E)-1-(5-Chloro-2-hydroxyphenyl)-3-{5-fluoro-2-[(1-phenyl-1 H-1, 2, 3-triazol-4-yl) methoxy] phenyl}-prop-2-en-1-one Derivatives"

"Synthesis and Antimicrobial Evaluation of (E)-1-(2, 4-Dichlorophenyl)-4-{3-methoxy-4-[(1-phenyl-1 H-1, 2, 3-triazol-4-yl) methoxy] benzylidene}-3-methyl-1 H-pyrazol-5 (4 H)-one Derivatives"

"Optimizing Parthenium waste: biomass-derived carbon adsorbents for adsorbing Amido Black 10B dye analyzed through graph theory for stability and reactivity"

"Synthesis and Antimicrobial Evaluation of (E)-2-(4-((4-((1-(2, 4-Dichlorophenyl)-3-methyl-5-oxo-1, 5-dihydro-4 H-pyrazol-4-ylidene) methyl)-2-methoxyphenoxy) methyl)-1 H-1, 2, 3-triazol-1-yl)-N-phenylacetamide Derivatives"

"Eco-friendly development of Leucas aspera-derived MoO3 nanoparticles: corrosion studies and multifunctional applications in medicine, agriculture, and industry"

"Optimized green synthesis of biocompatible Ag nanostructures using Artemisia Indica leaf extract: a promising avenue for biomedical applications"

"Facile and Proficient Synthesis of Some New 1,2,4-Triazole-3-Thiones Derivatives Using [H2-TMDP][HPO4] Ionic Liquid"

"Synthesis, Antimicrobial Evaluation, and Computational Study of Novel Fluorinated Benzofuran Derivatives"

"New 1, 2, 3‐Triazole‐Tethered Chalcone Derivatives: Synthesis, Bioevaluation and Computational Study"

"Design, Synthesis, Molecular Docking, and Anti-inflammatory Activity of 2-[(E)-{1-[4-(4-Chlorophenyl)-1, 3-thiazol-2-yl]-1H-pyrazol-4-yl}(hydroxyimino) methyl] phenol and {1-[4-(4-Chlorophenyl)-1, 3-thiazol-2-yl]-1H-pyrazol-4-yl}(2-hydroxyphenyl) methanone Derivatives"

Shadab Ahamad | Biochemistry, Genetics and Molecular Biology | Best Scholar Award

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Mr. Shadab Ahamad | Biochemistry, Genetics and Molecular Biology | Best Scholar Award

Sri Sathya Sai University for Human Excellence | India

Mr. Shadab Ahamad is a dedicated life sciences researcher specializing in biotechnology, genomics, and congenital heart disease (CHD) studies. He is currently pursuing a Ph.D. in Life Sciences at Sri Sathya Sai University for Human Excellence, focusing on unraveling genetic and environmental factors contributing to CHD through advanced genomic approaches such as GWAS, NGS, and variant screening. His academic background includes a B.Tech. in Biotechnology from GB Pant University of Agriculture and Technology, a DBT-sponsored Postgraduate Diploma in Agricultural Biotechnology from Amity Institute of Biotechnology, and research fellowships across prestigious institutes including JNCASR and IARI Delhi. Professionally, he serves as a Research Officer at Sri Sathya Sai Sanjeevani International Centre for Child Heart Care and Research, where he integrates clinical data analysis with genomic research to explore genotype-phenotype correlations and maternal-perinatal risk factors. His work spans plant biotechnology, nanotechnology integration, and clinical genomics, with multiple peer-reviewed research articles, reviews, and book chapters. Having presented at numerous international conferences and received recognition for his contributions, Mr. Ahamad continues to bridge translational research and clinical application to improve child health outcomes globally.

Profile : Orcid

Featured Publications

  • "Maternal Peri-Conceptional Sleep Quality and Risk of Congenital Heart Disease in Offspring: An Exploratory Case–Control Study"

  • "Developmental Origins of Health and Disease"

  • "Impact of long-term deep freeze storage on human leukocytes viability & DNA extraction: Insights from a resource-limited biorepository"

  • "Navigating Life with Rare Syndromes and Congenital Heart Disease: The Unseen Link"

  • "Is Poor Maternal Sleep Quality in the Periconceptional Period a Risk Factor for Congenital Anomalies in Offspring?"

  • "Systematic molecular view of targets prioritization of congenital heart disease against developmental toxicity"

  • "Paternal Teratogen Exposure and Risk of Congenital Heart Disease in Offspring: A Two-Year Retrospective Observational Study"

  • "Summary of initiatives for treating congenital heart disease: Enhancing quality of life and bridging the knowledge gap"

  • "Computational insights into maternal environmental pollutants and folate pathway regulation"

  • "Isolation and PCR Validation of DNA from Chicory (Cichorium intybus L.) Leaves Using an Optimized CTAB Method to Propel Medicinal Insights"