Zhejiang University | China
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Early Academic Pursuits
Dr. Bingbing Wu began his academic journey with a strong foundation in biological sciences and technology, later advancing to doctoral studies in animal science at Zhejiang University. His early academic training provided him with a deep understanding of cellular biology, developmental processes, and molecular mechanisms, which later became central to his research in regenerative medicine and women’s health. These formative years not only shaped his scientific curiosity but also set the stage for his future contributions to stem cell biology and tissue regeneration.
Professional Endeavors
Following his doctoral studies, Dr. Wu pursued postdoctoral research at Zhejiang University School of Medicine and The First Affiliated Hospital of Zhejiang University, where he investigated the molecular underpinnings of tissue regeneration and gynecological diseases. His professional path led him to roles as a research assistant, full-time researcher, and later junior principal investigator at Zhejiang University’s International School of Medicine. Each role deepened his expertise in applying cutting-edge technologies to complex medical problems and allowed him to cultivate leadership in research.
Contributions and Research Focus
Dr. Wu’s research is centered on stem cell biology, regenerative medicine, and women’s reproductive health. His work investigates key stem cells involved in endometrial development and regeneration, along with the regulatory mechanisms driving their differentiation. He applies single-cell and spatial multi-omics technologies to unravel the pathological basis of diseases such as intrauterine adhesions and preeclampsia. By integrating organoid models, he has advanced understanding of maternal-fetal interface formation and disease mechanisms, providing novel insights into therapeutic approaches for obstetric and gynecological conditions.
Accolades and Recognition
Throughout his career, Dr. Wu has earned prestigious recognition through numerous competitive research grants. He has been a principal investigator on projects funded by the National Natural Science Foundation of China and the Zhejiang Province Key Projects, reflecting the national and regional confidence in his scientific leadership. His publications in respected international journals such as ACS Applied Materials & Interfaces, Stem Cell Reports, Cell Discovery, and NPJ Regenerative Medicine highlight his contributions to the advancement of regenerative medicine and biomedical science.
Impact and Influence
Dr. Wu’s work has had a significant impact on the field of regenerative medicine, particularly in women’s reproductive health. His studies have not only elucidated molecular pathways of tissue development but also provided translational potential for developing bioactive materials and therapeutic interventions. By combining experimental and computational approaches, he has expanded the scope of regenerative research, inspiring peers and contributing to the global understanding of complex gynecological disorders.
Legacy and Future Contributions
As a scientist committed to innovation, Dr. Wu continues to push the boundaries of regenerative biology. His current projects focus on human adult uterine cell atlases, endometrial tissue engineering, and the role of specific stromal and immune cell populations in tissue regeneration. With ongoing leadership in funded projects and collaborations, he is shaping a scientific legacy that bridges fundamental biology with clinical application. His future contributions are expected to bring new hope for women suffering from reproductive health disorders.
Publications
Article: Autologous platelet-rich plasma dual-network hydrogel promotes human endometrial regeneration
Authors: Xiao Chen, Chengcheng Zhu, Lu Wang, Jialing Deng, Zhuomin Wang, Xiaolin Wu, Haimin Tan, Yiyuan Qu, Bingbing Wu, Yu Li, Keren Cheng, Jian Xu
Journal: Acta Biomaterialia
Year: 2025
Article: Natural regeneration-inspired sequential delivery of synergistic growth factors for structural and functional endometrial regeneration
Authors: Cheng Zhang, Chengcheng Zhu, Xiao Chen, Xuzhi Chen, Di Zhang, Huafei Zhao, Junwen Zhang, Yu Zhang, Wanwan Xu, Xiaofeng Zhao, Yingying Hu, Wei Wei, Jian Xu, Yu Li, Bingbing Wu
Journal: Acta Biomaterialia
Year: 2025
Article: Reshaping the chromatin landscape in HUVECs from small-for-gestational-age newborns
Authors: Lingling Yan, Zhimin Zhou, Shengcai Chen, Xin Feng, Junwen Mao, Fang Luo, Jianfang Zhu, Xiuying Chen, Yingying Hu, Yuan Wang, Bingbing Wu, Lizhong Du, Chunlin Wang, Liang Gong, Yanfen Zhu
Journal: JCI Insight
Year: 2025
Article: Size- and Dose-Dependent Body-Wide Organ Transcriptomic Responses to Calcium Phosphate Nanomaterials
Authors: Yu Li, Wei Jiang, Nanfang Nie, Jiaqi Xu, Xiaozhao Wang, Junwen Zhang, Jiahuan Guan, Chengcheng Zhu, Cheng Zhang, Ying Gu, Xiaoyi Chen, Shasha Yao, Zi Yin, Bingbing Wu*, Hongwei Ouyang*, Xiaohui Zou*
Journal: ACS Applied Materials & Interfaces
Year: 2023
Article: A Dual-Crosslinked Hydrogel Based on Gelatin Methacryloyl and Sulfhydrylated Chitosan for Promoting Wound Healing
Authors: Shunxian Ji, Yushuang Zhao, Xinrang Zhai, Lu Wang, Huali Luo, Zhiyong Xu, Wei Dong, Bingbing Wu*, Wei Wei*
Journal: International Journal of Molecular Sciences
Year: 2023
Conclusion
Dr. Bingbing Wu stands as a distinguished researcher whose academic dedication, professional achievements, and scientific contributions have left a lasting mark on regenerative medicine. His focus on stem cells, multi-omics, and endometrial regeneration has advanced both theoretical knowledge and applied therapeutic strategies. With continued research, mentorship, and innovation, he is poised to expand his influence further, leaving a legacy of discovery and practical impact in the field of health professions.