Meilang Xue | Medicine and Dentistry | Best Researcher Award

Assoc. Prof. Dr. Meilang Xue | Medicine and Dentistry | Best Researcher Award

University of Sydney | Australia

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Early Academic Pursuits 🎓

Assoc. Prof. Dr. Meilang Xue embarked on her academic journey with a strong passion for biomedical sciences. She earned her PhD from the University of New South Wales in 2002, laying the foundation for a distinguished career in molecular and cellular research. Her early academic years were marked by an inquisitive drive to uncover the intricate mechanisms of inflammatory and autoimmune diseases, setting the stage for groundbreaking discoveries in the field.

Professional Endeavors 🏢

Dr. Xue is currently the Head of the Sutton Arthritis Research Laboratory and the Chief Scientist of the A3BC Biobank at the Institute of Bone & Joint Research, Kolling Institute, University of Sydney. Since joining the Sutton Lab after her PhD, she has been instrumental in advancing the understanding of inflammatory and autoimmune diseases. Her leadership in these roles has facilitated significant research collaborations and the translation of scientific findings into potential therapeutic applications.

Contributions and Research Focus 🔬

Dr. Xue's research primarily explores the molecular and cellular mechanisms underpinning inflammatory and autoimmune conditions. She was the first to elucidate the critical role of the endothelial protein C receptor (EPCR) and its anti-clotting properties within the synovial joint and skin. These discoveries have revolutionized the understanding of rheumatoid arthritis, skin inflammation, and even type 1 diabetes. Her research has been widely recognized in high-impact journals such as Ann Rheum Dis, Arthritis Rheum, Rheumatology, and Journal of Investigative Dermatology. With 92 publications, 25 patents, and over 6,200 citations, her work has significantly contributed to medical science.

Accolades and Recognition 🏆

Dr. Xue's exemplary contributions have earned her numerous prestigious research fellowships and grants exceeding $5 million, funded by the NHMRC, Arthritis Australia, Lincoln Centre, JDRF International, and industry partners. She has been ranked as the 12th world-leading expert in endothelial protein C receptor research, placing her in the top 0.67% of published authors worldwide in this domain. Her h-index of 37 further underscores her influential impact on the field.

Impact and Influence 🌍

Beyond her research, Dr. Xue has played a crucial role in fostering the next generation of scientists. She has mentored and supervised numerous PhD candidates, postdoctoral fellows, honors students, and research assistants. As a committee member of the Kolling Institute’s Musculoskeletal Priority Research Area Leadership Group and the Kolling Research Enabler Group, she continues to shape the direction of musculoskeletal research. Additionally, her work with the A3BC as a Steering Committee member and chief scientist since 2017 has strengthened national and international research collaborations.

Legacy and Future Contributions 📚

Dr. Xue's dedication to scientific excellence ensures a lasting legacy in inflammatory and autoimmune disease research. Her ongoing studies into the protein C system’s role in disease modulation continue to inspire new therapeutic strategies. With her leadership in academia and industry collaborations, she is set to drive further advancements in precision medicine. Her unwavering commitment to research, mentorship, and innovation cements her reputation as a trailblazer in the field of molecular medicine.

Publications


  • đź“„ Endothelial Protein C Receptor: A Multifunctional Mediator in the Pathophysiology of Rheumatoid Arthritis
    Author(s): Meilang Xue, Lyn March
    Journal: Cells
    Year: 2025


  • đź“„ EPCR Deficiency Ameliorates Inflammatory Arthritis in Mice by Suppressing the Activation and Migration of T Cells and Dendritic Cells
    Author(s): Meilang Xue, Haiyan Lin, Hai Po Helena Liang, Christopher John Jackson, L. M. March
    Journal: Rheumatology (United Kingdom)
    Year: 2024


  • đź“„ Exploring the Association Between Circulating Endothelial Protein C Receptor and Disease Activity of Rheumatoid Arthritis in a Pilot Study
    Author(s): Meilang Xue, Haiyan Lin, Tom Lynch, Mihir Dilip Wechalekar, L. M. March
    Journal: Rheumatology Advances in Practice
    Year: 2024


  • đź“„ Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model
    Author(s): Meilang Xue, Christopher John Jackson, Haiyan Lin, John H. Griffin, L. M. March
    Journal: International Journal of Molecular Sciences
    Year: 2024


  • đź“„ Involvement of PAR-2 in the Induction of Cell-Specific Matrix Metalloproteinase-2 by Activated Protein C in Cutaneous Wound Healing
    Author(s): Sohel M. Julovi, Kelly J. McKelvey, Nikita Minhas, Meilang Xue, Christopher John Jackson
    Journal: International Journal of Molecular Sciences
    Year: 2024


 

Zhihan Zhu | Medicine and Dentistry | Best Researcher Award

Ms. Zhihan Zhu | Medicine and Dentistry | Best Researcher Award

Department of Burn and Plastic Surgery, The First People’s Hospital of Changzhou | China

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🎓 Early Academic Pursuits

Ms. Zhihan Zhu pursued her Bachelor’s degree at Nantong University, focusing on Clinical Medicine with a specialization in oncology. Her academic excellence earned her scholarships for three consecutive years, reflecting her dedication and outstanding performance throughout her studies. For her Master’s studies, she specialized in Burn and Plastic Surgery at Nantong University’s Xinglin College. Her education also included robust foundational courses in internal medicine, surgery, obstetrics, pediatrics, pathology, and anatomy.

🏥 Professional Endeavors

Ms. Zhu gained substantial clinical experience through internships and residencies at renowned hospitals, including the Jiangsu Provincial Yangzhou Jiangdu People's Hospital and Shanghai Minhang District Oncology Hospital. She excelled in surgical operations, patient management, and medical communication. Her expertise spans advanced techniques like autologous skin grafting, deep vein catheterization, and burn wound management. She also possesses proficiency in clinical documentation, prescription optimization, and patient interaction.

đź§Ş Contributions and Research Focus

Ms. Zhu’s research focuses on wound healing, tissue regeneration, and therapeutic advancements. Her notable projects include:

  • Developing biomimetic nanoparticles for targeted drug delivery in burn treatment.
  • Exploring the protective effects of artemisinin derivatives on liver damage post-burn injury.
  • Investigating adipose-derived stem cells in scar regeneration.

Her work has led to multiple scholarly publications as a primary or co-author, contributing significantly to advancements in burn surgery and regenerative medicine.

🏆 Accolades and Recognition

Ms. Zhu’s academic journey is marked by numerous honors, including the Master's Research Scholarship at Nantong University for three consecutive years. Her research contributions have been recognized by peers in the scientific community, reflecting her dedication and impact.

🌍 Impact and Influence

Ms. Zhu’s work in innovative surgical techniques and regenerative therapies is improving patient outcomes in burn care. Her ability to integrate clinical expertise with cutting-edge research demonstrates her influence in shaping future medical practices in her field.

🌟 Legacy and Future Contributions

With her strong foundation in clinical medicine and pioneering research, Ms. Zhu is poised to leave a lasting legacy in burn and plastic surgery. Her commitment to academic excellence and patient care will undoubtedly lead to transformative advancements in medicine.

 

Publications


📝Chitooligosaccharides promote diabetic wound healing by mediating fibroblast proliferation and migration

  • Authors: Li, Z., Zhang, C., Wang, L., Zhou, Y., Zhang, Y.
  • Journal: Scientific Reports
  • Year: 2025,

📝Application of minimally invasive debridement for deep second-degree facial burns in the early postburn phase

  • Authors: Zhang, C., Li, Z., Zhang, Q., Hu, K., Zhang, Y.
  • Journal: BMC Surgery
  • Year: 2025

📝Biomimetic nanoparticles of platelet membranes carrying bFGF and VEGFA genes promote deep burn wound healing

  • Authors: Wang, B., Chen, J., Zhang, C., Zhang, Y., Jiang, Y.
  • Journal: International Immunopharmacology
  • Year: 2023

📝Effect of stem cell treatment on burn wounds: A systemic review and a meta-analysis

  • Authors: Qiao, Y., Zhang, Q., Peng, Y., Li, Z., Zhang, Y.
  • Journal: International Wound Journal
  • Year: 2023

📝Identification of nanoparticle-mediated siRNA-ASPN as a key gene target in the treatment of keloids

  • Authors: Dong, Y., Zhang, C., Zhang, Q., Gu, H., Zhang, Y.
  • Journal: Frontiers in Bioengineering and Biotechnology
  • Year: 2022