MInjie Wang | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Prof. Minjie Wang | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Inner Mongolia Medical University | China

Prof. Minjie Wang is an accomplished biomedical researcher with a strong scholarly record, reflected by an h-index of 6, 15 peer-reviewed documents, and 93 citations. His research focuses on the discovery and functional characterization of active substances from Traditional Chinese Medicine and Mongolian Medicine, with particular emphasis on the pathological mechanisms of cardiovascular and cerebrovascular diseases and the identification of therapeutic drug targets. A major theme of his work is the role of AMP-activated protein kinase (AMPK) in vascular inflammation, endothelial dysfunction, atherosclerosis, metabolic syndrome, and adipose tissue remodeling. His studies integrate advanced in vivo animal models—including atherosclerosis, myocardial ischemia-reperfusion injury, arrhythmia, and cerebral ischemia—with comprehensive in vitro approaches encompassing cell culture, molecular biology, immunohistochemistry, and biochemical analysis. Prof. Wang has published extensively in high-impact journals such as European Heart Journal, Cell Death & Disease, Frontiers in Microbiology, Acta Pharmacologica Sinica, and European Journal of Pharmacology, contributing significant insights into vascular biology, inflammation, metabolism, and translational pharmacology. His work also includes patented innovations related to AMPK activators for vascular inflammation and endothelial protection, underscoring both scientific depth and translational relevance.

 

Citation Metrics (Scopus)

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Featured Publications

 

Lingmin Zhang | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Prof. Lingmin Zhang | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Guangzhou Medical University | China

Prof. Lingmin Zhang is a leading researcher whose work integrates pharmaceutics, biomedical materials, and gene delivery, contributing significantly to advanced therapeutic strategies, particularly in lung cancer and inflammatory diseases. With 3,077 citations , 79 publications, and an h-index of 27, the researcher's scholarly impact is widely recognized. The work focuses on innovative nano-based and biomimetic delivery platforms, including nano-PROTACs, exosomes, microfluidic nanovesicles, and CRISPR/Cas9 carriers, offering transformative possibilities for targeted and precision medicine. Supported by major grants from the National Natural Science Foundation of China (projects 82572415, 82072047, 81700382), the researcher has developed cutting-edge strategies such as reprogramming tumor-associated macrophages, overcoming drug resistance in lung cancer, and reversing epigenetic silencing through nanoparticle-mediated gene delivery. Influential publications in high-impact journals—including Journal of Controlled Release, Drug Resistance Updates, ACS Nano, Angewandte Chemie, Advanced Science, and Molecular Cancer—highlight breakthroughs in nano-therapeutics, PROTAC technologies, artificial exosomes, and nucleic-acid delivery systems. Collectively, these contributions position the researcher at the forefront of translational nanomedicine, with ongoing work offering new directions for precision oncology, regenerative strategies, and next-generation drug delivery platforms.

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Featured Publication

He, M., Peng, Q., Yang, Q., Guan, X., Liu, Q., Chen, R., Zhou, D., Wang, L., Zhang, Y., Li, S., Su, J., & Zhang, L. (2026). In situ reprogramming of tumor associated macrophages with versatile nano-epigenetic inhibitor for lung cancer therapy. Journal of Controlled Release, 2026, 114497.

Zhang, L., He, L., Lin, Y., Wei, J., Tang, S., Lei, X., Lin, X., Zhou, D., Fu, L., Li, Y., He, J., Liang, L., & Yu, X. (2026). The novel strategy to overcome drug-resistant lung cancer: Dual targeting delivery of PROTAC to inhibit cancer-associated fibroblasts and lung cancer cells. Drug Resistance Updates, 84, 101316.

Chen, S., Chen, E., Su, J., Gong, Y., Tang, S., Qin, A., Shen, A., Tang, S., & Zhang, L. (2025). Magnetically navigated nano-PROTAC ameliorates acute lung injury. Journal of Nanobiotechnology, 23, 622.

Li, X., Qin, Z., Wang, S., Zhang, L., & Jiang, X. (2025). Microfluidics-assembled nanovesicles for nucleic acid delivery. Accounts of Chemical Research, 58, 570–582.

Liang, L., Peng, W., Qin, A., Zhang, J., Chen, R., Zhou, D., Zhang, X., Zhou, N., Yu, X., & Zhang, L. (2024). Intracellularly synthesized artificial exosome treats acute lung injury. ACS Nano, 18(32), 21009–21023.

Guan, X., Xu, X., Tao, Y., Deng, X., He, L., Lin, Z., Chang, J., Huang, J., Zhou, D., Yu, X., Wei, M., & Zhang, L. (2024). Dual targeting and bioresponsive nano-PROTAC induced precise and effective lung cancer therapy. Journal of Nanobiotechnology, 22, 692.

Zhang, L., Lin, Y., Li, S., Guan, X., & Jiang, X. (2023). In situ reprogramming of tumor-associated macrophages with internally and externally engineered exosomes. Angewandte Chemie International Edition, 62(11), e202217089.

Liang, L., Cen, H., Huang, J., Qin, A., Xu, W., Wang, S., Chen, Z., Tan, L., Zhang, Q., Yu, X., Yang, X., & Zhang, L. (2022). The reversion of DNA methylation-induced miRNA silence via biomimetic nanoparticles-mediated gene delivery for efficient lung adenocarcinoma therapy. Molecular Cancer, 21(1), 186.

Zhang, H., Peng, R., Chen, S., Shen, A., Zhao, L., Tang, W., Wang, X., Li, Z., Zha, Z., Yi, M., & Zhang, L. (2022). Versatile nano-PROTAC-induced epigenetic reader degradation for efficient lung cancer therapy. Advanced Science, 9(29), 2202039.

Zhang, L., Wang, L., Xie, Y., Wang, P., Deng, S., Qin, A., Zhang, J., Yu, X., Zheng, W., & Jiang, X. (2019). Triple-targeting delivery of CRISPR/Cas9 to reduce the risk of cardiovascular diseases. Angewandte Chemie International Edition, 58(36), 12404–12408.

Zhuowei Luo | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Mr. Zhuowei Luo | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Hubei University of Chinese Medicine | China

Mr. Zhuowei Luo is an emerging researcher recognized for effectively integrating classical Traditional Chinese Medicine (TCM) theory with modern biomedical science, demonstrating strong expertise in molecular mechanism analysis and advanced metabolomics for chronic disease research. His notable scientific contribution is a co-authored publication in the Journal of Ethnopharmacology (Q2, IF 5.14), where he helped elucidate how Allium macrostemon delays chronic renal failure by modulating the IL-17 signaling pathway and altering tryptophan and glycerophospholipid metabolism. This work represents the first comprehensive study connecting immunological regulation with multi-omics profiling to explain the therapeutic mechanisms of this TCM herb, providing a meaningful model for modernizing traditional medicine through systems biology. His role in the project included designing and validating qPCR primers, conducting network pharmacology to identify key molecular targets, performing metabolomics and transcriptomics data analyses, and carrying out histopathological assessments. Through these contributions, he demonstrated an advanced ability to apply interdisciplinary approaches—combining immunology, pharmacology, and bioinformatics—to uncover mechanistic insights into natural product–based interventions. His research reflects scientific maturity beyond typical early-stage experience and contributes to the growing evidence supporting data-driven modernization of TCM in chronic disease treatment.

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Featured Publication

Zhao, Y., Ge, J. X., Zhang, N., Lei, Z. X., Sun, S. Y., Luo, Z. W., Yang, Y. F., & Wu, H. Z. (2025). Allium macrostemon Bge. delays chronic renal failure by modulating IL-17 signaling pathway and affecting tryptophan/glycerophospholipid metabolism. Journal of Ethnopharmacology, 120946.

Annalisa Bosi | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Annalisa Bosi | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

University of Insubria | Italy

Dr. Annalisa Bosi is a distinguished researcher with 909 citations, 29 scientific documents, and an h-index of 15, reflecting her strong impact in the fields of immunology, gastrointestinal pathology, and microbiota–gut–brain axis research. Her early work focused on the phenotypic and functional characterization of innate immune components, particularly NK cells and macrophages, examining their role in tumor pathogenesis and their modulation by chemotherapeutic agents or plant-derived molecules. She later advanced her research to explore molecular and cellular mechanisms underlying major gastrointestinal diseases such as ischemia, intestinal inflammation, and enteric neuropathy, identifying the regulatory role of hyaluronic acid homeostasis in tissue repair. Her recent studies investigate gut microbiota, dysbiosis, and their influence on neurodevelopment and tumor etiopathogenesis, with growing emphasis on prebiotic and probiotic interventions. Dr. Bosi has contributed significantly to understanding experimental models of gut pathology, neuromuscular dysfunction, immunomodulation by virome components, and sex-dependent microbial effects. Her publications span high-impact journals, covering topics such as microbiota–immune interactions, ischemia–reperfusion injury, cytokine–phage crosstalk, and neuroimmune modulation. Through multidisciplinary approaches integrating molecular biology, immunology, and neurogastroenterology, her work continues to shape emerging perspectives on host–microbiota communication and its relevance to disease mechanisms and therapeutic strategies.

Profiles : Scopus | Orcid

Featured Publications

Bosi, A., Baranzini, N., Ponti, A., Moretto, P., Moro, E., Crema, F., Cianci, R., Karousou, E., Viola, M., Passi, A., et al. (2025). Intestinal ischemia/reperfusion injury influences hyaluronan homeostasis in the rat brain. International Journal of Molecular Sciences, 26(20), 10064.

Cianci, R., Caldarelli, M., Brani, P., Bosi, A., Ponti, A., Giaroni, C., & Baj, A. (2025). Cytokines meet phages: A revolutionary pathway to modulating immunity and microbial balance. Biomedicines, 13(5), 1202.

Faggin, S., Cerantola, S., Caputi, V., Tietto, A., Stocco, E., Bosi, A., Ponti, A., Bertazzo, A., Macchi, V., Porzionato, A., et al. (2025). Toll-like receptor 4 deficiency ameliorates experimental ileitis and enteric neuropathy: Involvement of nitrergic and 5-hydroxytryptaminergic neurotransmission. British Journal of Pharmacology, 182(8), 1803–1822.

Brani, P., Manzoor, H. Z., Spezia, P. G., Vigezzi, A., Ietto, G., Dalla Gasperina, D., Minosse, C., Bosi, A., Giaroni, C., Carcano, G., et al. (2025). Torque Teno Virus: Lights and shades. Viruses, 17(3), 334.

Dal Lago, S., Brani, P., Ietto, G., Dalla Gasperina, D., Gianfagna, F., Giaroni, C., Bosi, A., Drago Ferrante, F., Genoni, A., Manzoor, H. Z., et al. (2024). Torque Teno Virus: A promising biomarker in kidney transplant recipients. International Journal of Molecular Sciences, 25(14), 7744.

Giambra, V., Pagliari, D., Rio, P., Totti, B., Di Nunzio, C., Bosi, A., Giaroni, C., Gasbarrini, A., Gambassi, G., & Cianci, R. (2023). Gut microbiota, inflammatory bowel disease, and cancer: The role of guardians of innate immunity. Cells, 12(22), 2654.

Bosi, A., Banfi, D., Bistoletti, M., Catizzone, L. M., Chiaravalli, A. M., Moretto, P., Moro, E., Karousou, E., Viola, M., Giron, M. C., et al. (2022). Hyaluronan regulates neuronal and immune function in the rat small intestine and colonic microbiota after ischemic/reperfusion injury. Cells, 11(21), 3370.

Bosi, A., Banfi, D., Bistoletti, M., Moretto, P., Moro, E., Crema, F., Maggi, F., Karousou, E., Viola, M., Passi, A., et al. (2021). Hyaluronan: A neuroimmune modulator in the microbiota–gut axis. Cells, 11(1), 126.

Cerantola, S., Caputi, V., Contarini, G., Mereu, M., Bertazzo, A., Bosi, A., Banfi, D., Mantini, D., Giaroni, C., & Giron, M. C. (2021). Dopamine transporter genetic reduction induces morpho-functional changes in the enteric nervous system. Biomedicines, 9(5), 465.

Banfi, D., Moro, E., Bosi, A., Bistoletti, M., Cerantola, S., Crema, F., Maggi, F., Giron, M. C., Giaroni, C., & Baj, A. (2021). Impact of microbial metabolites on microbiota–gut–brain axis in inflammatory bowel disease. International Journal of Molecular Sciences, 22(4), 1623.

Baci, D., Bosi, A., Parisi, L., Buono, G., Mortara, L., Ambrosio, G., & Bruno, A. (2020). Innate immunity effector cells as inflammatory drivers of cardiac fibrosis. International Journal of Molecular Sciences, 21(19), 7165.

Baci, D., Bosi, A., Gallazzi, M., Rizzi, M., Noonan, D. M., Poggi, A., Bruno, A., & Mortara, L. (2020). The ovarian cancer tumor immune microenvironment (TIME) as target for therapy: A focus on innate immunity cells as therapeutic effectors. International Journal of Molecular Sciences, 21(9), 3125.

Bosi, A., Banfi, D., Bistoletti, M., Giaroni, C., & Baj, A. (2020). Tryptophan metabolites along the microbiota–gut–brain axis: An interkingdom communication system influencing the gut in health and disease. International Journal of Tryptophan Research, 13, 1–18.

Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Prof. Dr. Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Soonchunhyang University | South Korea

Prof. Dr. Keon-Hyoung Song is a distinguished researcher whose work bridges pharmaceutical sciences, drug delivery systems, and pharmacokinetics. With 708 citations, 27 scholarly publications, and an h-index of 13, his research has significantly advanced the understanding of membrane permeation enhancers, drug formulation, and solubilization strategies. His extensive portfolio includes high-impact studies on intestinal absorption mechanisms, cocrystal engineering, and pharmacokinetic optimization, published in reputed journals such as Pharmaceutics, European Journal of Medicinal Chemistry, and Journal of Controlled Release. Prof. Song’s innovations extend beyond academia, with over 25 international patents registered across the U.S., Europe, and Korea, focusing on permeation-enhancing peptides, liposomal carriers, and pharmaceutical formulations. His pioneering patents, including those on mucous membrane permeation peptides (EP 3875103, 2025) and sugar alcohol-based liposome compositions, underscore his role in translating laboratory discoveries into therapeutic applications. Licensed as both a Patent Attorney and a Pharmacist, he effectively integrates regulatory insight with scientific innovation. Prof. Song’s sustained contributions to quantitative drug analysis using LC-MS and formulation optimization have made him a leading figure in advancing next-generation drug delivery technologies and pharmaceutical development.

Profile : Scopus

Featured Publications

Jeong, D.-H., Kim, J.-W., & Song, K.-H. (2025). Improved intestinal permeation of cyclosporin A by FCIGRL-modified tight junction modulator in rats. Pharmaceutics, 17(11), 1395.

Park, G., Galdamez, A., Song, K.-H., Le, M., Kim, K., & Lin, J. H. (2024). Ethnic variation and structure–function analysis of tauopathy-associated PERK alleles. Israel Journal of Chemistry, 64(12).

Song, K.-H. (2024). Effect of tight junction-modulating FCIGRL-modified peptides on the intestinal absorption of doxorubicin in rats. Pharmaceutics, 16(5), 650.

Jiang, F.-L., Jeong, D.-H., Eom, S.-H., Lee, H.-M., Cha, B.-J., Park, J.-S., Kwon, R.-K., Nam, J.-Y., Yu, H.-S., Heo, S.-H., Kim, C.-H., & Song, K.-H. (2024). Effects of enteric-coated formulation of sodium bicarbonate on bicarbonate absorption and gastrointestinal discomfort. Nutrients, 16(5), 744.

Koo, N. R., Yoon, S., Song, K.-H., Baek, M. J., Jeon, S., & Im, J. (2024). Tumor-homing peptide iRGD-conjugate enhances tumor accumulation of camptothecin for colon cancer therapy. European Journal of Medicinal Chemistry, 265, 116050.

Park, G., Xu, K., Chea, L., Kim, K., Safarta, L., Song, K.-H., Wu, J., Park, S., Min, H., Hiramatsu, N., Han, J., & Lin, J. H. (2023). Neurodegeneration risk factor EIF2AK3 (PERK) influences tau protein aggregation. The Journal of Biological Chemistry, 299(2), 102821.

Eom, Y. S., Jeong, D., Ryu, A.-R., Song, K.-H., Im, D. S., & Lee, M.-Y. (2022). Daphne odora exerts depigmenting effects via inhibiting CREB/MITF and activating AKT/ERK-signaling pathways. Current Issues in Molecular Biology, 44(8), 3312–3323.

Kim, H., Song, K.-H., Ambegaonkar, J. P., Chung, S., Jeon, K., Jiang, F. L., Eom, J. J., & Kim, C.-H. (2022). Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people. BMC Geriatrics, 22(1), 385.

Jiang, F., Tang, S., Eom, J.-J., Song, K.-H., Kim, H., Chung, S., & Kim, C.-H. (2022). Accuracy of estimated bioimpedance parameters with octapolar segmental bioimpedance analysis. Sensors, 22(7), 2681.

Yoon, Y. M., Lee, J. H., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins. Journal of Pineal Research, 68(3), e12632.

Lee, J. H., Yoon, Y. M., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. Aging Cell, 19(3), e13111.

Cha, S. J., Choi, H.-J., Kim, H.-J., Choi, E. J., Song, K.-H., Im, D. S., & Kim, K. (2020). Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. Insect Molecular Biology, 29(1), 56–65.*

Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Mrs. Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Medical University-Plovdiv | Bulgaria

Mrs. Valentina Mihaylova is a dedicated researcher and specialist in medical chemistry with a strong focus on cellular metabolism, mitochondrial function, oxidative stress, and autoimmune diseases. With an h-index of 2, she has authored five scientific publications, which have collectively garnered 14 citations, reflecting her growing impact in medical biology and clinical research. Her work encompasses the study of markers of oxidative stress and insulin resistance in chronic autoimmune Hashimoto’s thyroiditis, cellular metabolic profiling in children with autism spectrum disorders, and the evaluation of therapeutic effects in rheumatoid arthritis through mitochondrial function and bioenergetic metabolism. Mrs. Mihaylova’s research also explores intestinal permeability, systemic inflammation, and the pharmacological effects of treatments such as methotrexate and JAK inhibitors on mitochondrial function and oxidative stress. She has actively contributed to numerous national and international conferences, presenting pioneering findings on the role of mitochondria, autophagy, and inflammation in autoimmune and rheumatologic conditions. Her academic and professional trajectory, spanning positions from clinical chemist to Master of Medical Chemistry at the Medical University of Plovdiv, is marked by a commitment to advancing knowledge in medical biology and translational research. Through her multidisciplinary approach, Mrs. Mihaylova continues to elucidate complex biochemical mechanisms underlying disease pathology and therapeutic responses, establishing herself as an emerging contributor to the field of medical and clinical biochemistry.

Profiles : Scopus | Orcid

Featured Publications

Mihaylova, V., Tomov, D., Karalilova, R., Batalov, Z., Batalov, A., Sarafian, V., & Kazakova, M. (2025). Effects of methotrexate and tofacitinib on mitochondrial function and oxidative stress in human synovial cells in vitro. International Journal of Molecular Sciences, 26(17), 8173.

Tomov, D. G., Levterova, B. A., Mihaylova, V. N., Troev, D. M., Miteva, M. Z., Uzunova, Y. I., & Orbetzova, M. M. (2024). Influence of the increase in intestinal permeability and microbiota change in the development of Hashimoto's thyroiditis: A systematic review. Endocrine and Metabolic Science, 100195.

Mihaylova, V., Kazakova, M., Batalov, Z., Karalilova, R., Batalov, A., & Sarafian, V. (2023). JAK inhibitors improve ATP production and mitochondrial function in rheumatoid arthritis: A pilot study. Rheumatology International.

Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Assist. Prof. Dr. Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Macau University Of Science And Technology | Macau

Assist. Prof. Dr. Panpan Hou is a distinguished researcher in the field of Biomedical Engineering and Biophysics, with a prolific record of 375 documents, 541 citations, and an h-index of 16. After obtaining a B.S. in Biomedical Engineering and a Ph.D. in Biophysics from Huazhong University of Science and Technology, Dr. Hou completed postdoctoral training at Washington University in St. Louis before joining Macau University of Science and Technology as an Assistant Professor in 2021. Dr. Hou’s research focuses on ion channel physiology, voltage-sensor domain (VSD) mechanisms, and electro-mechanical coupling, elucidating complex molecular processes such as the VSD-pore coupling in KCNQ1 channels and identifying novel modulators with therapeutic potential. He has made significant contributions to drug screening, cardiovascular disease modeling, and electrophysiology, publishing high-impact work in journals including Nature Communications, PNAS, eLife, Circulation Research, and Scientific Reports. Dr. Hou has received multiple awards including the AHA Postdoctoral Fellowship, Best Poster Awards at international symposia, and the 2025 Best Research Output Award from Macau University of Science and Technology. Beyond research, he actively mentors students, serves on editorial boards, and contributes to national and international scientific societies. With a strong track record of innovation, mentorship, and high-impact publications, Dr. Hou exemplifies excellence in biomedical research and is poised to advance the understanding of ion channel physiology and therapeutic interventions.

Profiles : Scopus | Orcid | Google Scholar

Featured Publications

Zhong, L., Lin, X., Cheng, X., Wan, S., Hua, Y., Nan, W., Hu, B., Peng, X., Zhou, Z., Zhang, Q., Yang, H., Noé, F., Yan, Z., Jiang, D., Zhang, H., Liu, F., Xiao, C., Zhou, Z., Mou, Y., Yu, H., Ma, L., Huang, C., Wong, V. K. W., Chung, S. K., Shen, B., Jiang, Z.-H., Neher, E., Zhu, W., Zhang, J., & Hou, P. (2025). Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating. Cell Research.

Hou, P., Zhao, L., Zhong, L., Shi, J., Wang, H. Z., Gao, J., Liu, H., Zuckerman, J., Cohen, I. S., & Cui, J. (2024). The fully activated open state of KCNQ1 controls the cardiac “fight-or-flight” response. PNAS Nexus.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2022). Author correction: A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Dou, A., Kang, P. W., Hou, P., Zaydman, M. A., Zheng, J., Jegla, T., & Cui, J. (2021). Principles of sensor-effector organization in six-transmembrane ion channels.

Lin, Y., Grinter, S. Z., Lu, Z., Xu, X., Wang, H. Z., Liang, H., Hou, P., Gao, J., Clausen, C., & Shi, J. (2021). Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. Proceedings of the National Academy of Sciences.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2020). A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Taylor, K. C., Kang, P. W., Hou, P., Yang, N.-D., Kuenze, G., Smith, J. A., Shi, J., Huang, H., McFarland White, K., & Peng, D. (2020). Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. eLife.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2020). Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation. Nature Communications.

Zhu, W., Mazzanti, A., Voelker, T. L., Hou, P., Moreno, J. D., Angsutararux, P., Naegle, K. M., Priori, S. G., & Silva, J. R. (2019). Predicting patient response to the antiarrhythmic mexiletine based on genetic variation: Personalized medicine for long QT syndrome. Circulation Research.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2019). Two-stage electro-mechanical coupling of a KV channel in voltage-dependent activation.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling. eLife.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances pore opening of KCNQ1 with VSD at the activated state by modulating VSD-pore coupling.

Hou, P., Eldstrom, J., Shi, J., Zhong, L., McFarland, K., Gao, Y., Fedida, D., & Cui, J. (2017). Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening. Nature Communications.

John Matsoukas | Chemistry | Excellence in Innovation Award

Prof. John Matsoukas | Chemistry | Excellence in Innovation Award

University of Patras | Greece

Professor John Matsoukas is a distinguished scholar in the field of chemistry and drug discovery, with over four decades of academic and research contributions spanning peptide chemistry, medicinal chemistry, and rational drug design. He has served as Professor of Chemistry at the University of Patras since 1995 and has held multiple visiting and adjunct appointments internationally, reflecting his global academic influence. His pioneering work in the design of non-peptide mimetics for peptide hormones and immune-related targets has significantly advanced research in hypertension, cancer, multiple sclerosis, and antiviral therapeutics. A prolific author, he has published 189 peer-reviewed papers, 50 book chapters, and numerous conference proceedings, bringing his total scholarly outputs to more than 600. His research has been widely recognized, accumulating over 5,500 citations and an h-index of 42, underscoring both productivity and impact within the scientific community. In addition, his innovative contributions are reflected in multiple patents, editorial roles, and his leadership in founding the Graduate Program in Medicinal Chemistry: Drug Discovery and Design, the first Euromaster-awarded program in Greece. Beyond academia, he has also established spin-offs and startups, securing over €15 million in grants, and continues to shape international biomedical networks, cementing his legacy as a leading figure in drug discovery and medicinal chemistry.

Profile : Scopus | Orcid

Featured Publications

"Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and Addiction"

"Gating Mechanism for Biased Agonism at Angiotensin II Type 1 Receptors"

"Semi-Supervised Learning for Predicting Multiple Sclerosis"

"Computational Evidence for Bisartan Arginine Blockers as Next-Generation Pan-Antiviral Therapeutics Targeting SARS-CoV-2, Influenza, and Respiratory Syncytial Viruses"

"A methamphetamine vaccine using short monoamine and diamine peptide linkers and poly-mannose"

"Density functional theory and enzyme studies support interactions between angiotensin receptor blockers and angiotensin converting enzyme-2: Relevance to coronavirus 2019"

"Myelin Oligodendrocyte Glycoprotein (MOG)35–55 Mannan Conjugate Induces Human T-Cell Tolerance and Can Be Used as a Personalized Therapy for Multiple Sclerosis"

"Structural Features Influencing the Bioactive Conformation of Angiotensin II and Angiotensin A: Relationship between Receptor Desensitization, Addiction, and the Blood–Brain Barrier"

Masroor Badshah | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Masroor Badshah | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Monash University | Australia

Author Profile

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Early Academic Pursuits

Dr. Masroor Badshah’s academic foundation is marked by a rigorous pursuit of medicine and anatomical sciences. Beginning with his degree in Medicine and Surgery, he developed an early research interest in the clinical relevance of anatomy, completing projects on skin diseases and vascular variations. His postgraduate studies at the University of Dundee expanded his expertise into human anatomy, where he defended a dissertation on carotid artery variations. This path led him to Monash University, where he earned his doctorate in medicine, focusing on oxytocin signaling in regulating the myogenic tone of the prostate and bladder. These early endeavors established a solid base for his later contributions to pharmacology and biomedical sciences.

Professional Endeavors

Dr. Badshah’s professional journey spans multiple countries, reflecting both versatility and international recognition. He began his teaching career as a lecturer and assistant professor in human anatomy at medical institutions in Pakistan before moving to Scotland and later Australia. His teaching associate roles at Monash University and research assistantship at the Monash Institute of Pharmaceutical Sciences allowed him to mentor students, design innovative teaching methodologies, and participate in collaborative research. His clinical internships in medicine and surgery also provided him with practical exposure that enriched his academic and research perspectives.

Contributions and Research Focus

At the core of Dr. Badshah’s career lies his dedication to advancing knowledge in pharmacology, toxicology, and pharmaceutical sciences. His doctoral work investigated the pharmacological role of oxytocin receptor antagonists in bladder and prostate function, with implications for overactive bladder treatments. His broader research includes studies in human surface anatomy, craniofacial asymmetry, morphometry of skeletal structures, and the clinical relevance of anatomical variations. By combining anatomical precision with pharmacological inquiry, he bridges the gap between foundational science and therapeutic application.

Accolades and Recognition

Throughout his career, Dr. Badshah has been honored with prestigious awards and scholarships, including the Monash Graduate Scholarship, Faculty International Tuition Scholarship, and the University of Dundee Tuition Scholarship. His academic excellence is reflected in multiple publications in peer-reviewed journals such as Biomedicines, Clinical Anatomy, and the Italian Journal of Anatomy and Embryology. He has also been a frequent presenter at international conferences, where his research findings on oxytocin signaling and anatomical morphometry have received recognition from the scientific community.

Impact and Influence

Dr. Badshah’s influence extends beyond research publications to shaping the next generation of medical and pharmaceutical scientists. His teaching philosophy emphasizes critical thinking, active participation, and evidence-based learning. By integrating innovative methodologies and fostering a collaborative learning environment, he has left a lasting impression on his students across different institutions. His work in surface anatomy and pharmacological sciences contributes to both clinical education and translational research, making his influence both academic and practical.

Legacy and Future Contributions

As a researcher with interdisciplinary expertise, Dr. Badshah’s legacy lies in his ability to merge anatomy with pharmacology for improved clinical outcomes. His ongoing research into bladder and prostate physiology offers potential breakthroughs in addressing urological disorders. Looking ahead, he aims to expand his collaborations globally, secure independent research leadership, and explore translational aspects of his work that could lead to therapeutic innovations. His legacy will continue to inspire young researchers and contribute to the evolution of biomedical sciences.

Publication


Investigating the Pharmacological Impact of Atosiban, an Oxytocin Receptor Antagonist, on Bladder and Prostate Contractions Within Obese and Non-Obese Rats
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Sarah M. Turpin-Nolan, Khaled A. Elnahriry, Ralf Middendorff, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2025


Age-Dependent Effects of Oxytocin and Oxytocin Receptor Antagonists on Bladder Contractions: Implications for the Treatment of Overactive Bladder Syndrome
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Ralf Middendorff, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2024


The Effects of Age on Prostatic Responses to Oxytocin and the Effects of Antagonists
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2023


Type of Treatment Supporters in Successful Completion of Tuberculosis Treatment: A Retrospective Cohort Study in Pakistan
Authors: Sana Hussain, Jamshed Hasnain, Zareen Hussain, Masroor Badshah, Hafeez Siddique, Christina Fiske, April Pettit
Journal: The Open Infectious Diseases Journal
Year: 2018


Morphology of the Human Hard Palate: A Study on Dry Skulls
Authors: Masroor Badshah, Roger Soames, Muhammad Jaffar Khan, Jamshaid Hasnain
Journal: Italian Journal of Anatomy and Embryology
Year: 2018


Conclusion

Dr. Masroor Badshah exemplifies the qualities of a dedicated academic, skilled researcher, and inspiring mentor. His career trajectory reflects a balance of teaching, research, and clinical exposure, with a focus on advancing pharmacology and anatomical sciences. His publications, conference presentations, and mentoring of students have strengthened his academic influence, while his research contributions offer practical applications in medicine. With a strong foundation and a vision for global collaboration, Dr. Badshah’s journey positions him as a leading figure in biomedical and pharmaceutical research, making his recognition as a distinguished researcher both timely and well-deserved.

Adarsh Kumar Shukla | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Adarsh Kumar Shukla | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Bhimrao Ramji Ambedkar Government Medical College | India

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Early Academic Pursuits

Dr. Adarsh Kumar Shukla laid the foundation of his academic journey with a strong inclination towards life sciences and biological research. Beginning with a degree in Biotechnology, he cultivated a passion for understanding molecular processes and biological systems. His interest in computational and applied biological sciences further deepened during his Master’s studies in Bioinformatics, where he explored the integration of biology with computational technologies. This academic progression culminated in a doctoral degree in Nutrition Biology from the Central University of Haryana, where he investigated nutraceutical compounds, molecular therapeutics, and bioinformatics-based approaches to health and nutrition. His early academic pursuits reflect a strong balance between theoretical learning, laboratory training, and computational applications in life sciences.

Professional Endeavors

Dr. Shukla’s professional career demonstrates a consistent alignment with advanced biomedical research and innovation. He began as a Research Associate and later served as a Scientist in the Department of Paediatric Cardiac Research at Sri Sathya Sai Sanjeevani Research Foundation, contributing to projects on congenital heart diseases and molecular mapping of environmental toxicants. His current role as Scientist-B in the Multidisciplinary Research Unit at Dr. Bhimrao Ramji Ambedkar Government Medical College, Kannauj, highlights his continued commitment to translational biomedical research. Alongside, he has engaged in teaching and faculty development programs, coordinated national scientific conclaves, and participated in capacity-building initiatives in healthcare and nutrition sciences.

Contributions and Research Focus

Dr. Shukla’s research spans a wide spectrum, encompassing structural bioinformatics, human genomics, and nutritional biology. His investigations range from identifying novel bioactive compounds in millets and medicinal plants to computationally mapping toxicants responsible for congenital disorders. His work on psychobiotics and gut-brain regulation has added new insights into neuropsychological health, while his contributions in plant-informatics shed light on the therapeutic potential of natural compounds against viral and bacterial diseases. Additionally, his focus on food-informatics and nutrigenomics has emphasized the role of probiotics, dietary fibers, and bioengineered foods in human health. Through a combination of in-silico and in-vitro studies, his work bridges computational biology with clinical and nutritional sciences.

Accolades and Recognition

Over the course of his career, Dr. Shukla has been recognized for his scientific excellence through awards, patents, and international presentations. He achieved distinction at global scientific forums, securing recognition for his molecular insights into congenital heart disease. His granted Indian patent on crab-apple-based jelly sheets demonstrates his inventive ability to connect traditional resources with modern food biotechnology. Furthermore, his peer-review contributions for high-impact journals and invited roles as a book reviewer underline his standing in the academic community. These achievements illustrate his ability to merge innovation with scholarly rigor.

Impact and Influence

The impact of Dr. Shukla’s research is evident in the interdisciplinary nature of his contributions. His computational models for drug discovery, therapeutic peptides, and congenital heart disease targets provide frameworks for future translational research. His coordination of events such as National Nutrition Month and Women in STEM conclaves reflects his commitment to societal awareness and academic empowerment. By blending computational biology with real-world health challenges, he has influenced research directions in reproductive toxicology, nutraceutical development, and environmental genomics, thereby shaping both scientific knowledge and public health practices.

Legacy and Future Contributions

Dr. Shukla’s academic and professional trajectory reflects the making of a researcher whose work is deeply rooted in societal relevance and interdisciplinary innovation. His legacy lies in advancing computational nutrition biology and medical informatics to address complex health challenges. Looking ahead, his ongoing projects on congenital heart disease, exposome mapping, and nutratherapeutics hold the promise of contributing to precision medicine and sustainable food innovations. His future contributions are likely to expand the integration of bioinformatics with clinical sciences, reinforcing his role as a bridge between molecular insights and healthcare applications.

Present Affiliation

Dr. Adarsh Kumar Shukla is currently serving as Scientist-B in the Multidisciplinary Research Unit at Dr. Bhimrao Ramji Ambedkar Government Medical College, Kannauj, Uttar Pradesh. His role reflects his dedication to advancing multidisciplinary biomedical research with a focus on translational outcomes for healthcare.

Publications


Article: Computational insights into maternal environmental pollutants and folate pathway regulation
Authors: Adarsh Kumar Shukla, Shadab Ahamad, Prachi Kukshal
Journal: Reproductive Toxicology
Year: 2025


Article: Virtual screening of potential orally active anti-bacterial compounds of finger millet
Authors: Raushan Kumar Jha, Adarsh Kumar Shukla, Anita Kumari, Ashwani Kumar
Journal: Vegetos
Year: 2024


Article: Identification of micronutrient deficiency related miRNA and their targets in Triticum aestivum using bioinformatics approach
Authors: Surbhi Panwar, Sunita Pal, Adarsh Kumar Shukla, Ashwani Kumar, Pradeep Kumar Sharma
Journal: Ecological Genetics and Genomics
Year: 2024


Article: Effect of processing techniques on functional, antioxidants, and structural properties of finger millet (Eleusine coracana) flour
Authors: Arzoo, Neeru, Adarsh Kumar Shukla, Surbhi Panwar, Ashwani Kumar
Journal: Food and Humanity
Year: 2024


Article: Nutritional evaluation of probiotics enriched rabadi beverage (PERB) and molecular mapping of digestive enzyme with dietary fibre for exploring the therapeutic potential
Authors: Prakash Yadav, Adarsh Kumar Shukla, Deepika, Neeru, Anita Kumari, Tejpal Dhewa, Ashwani Kumar
Journal: Food and Humanity
Year: 2024


Conclusion

In summary, Dr. Shukla embodies the qualities of a multidisciplinary scientist who blends innovation with social responsibility. His research not only advances scientific understanding but also carries tangible implications for human health and nutrition. With his current role in a government medical research unit and his wide-ranging expertise, he is poised to make enduring contributions to biomedical sciences, food biotechnology, and public health.