Annalisa Bosi | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Annalisa Bosi | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

University of Insubria | Italy

Dr. Annalisa Bosi is a distinguished researcher with 909 citations, 29 scientific documents, and an h-index of 15, reflecting her strong impact in the fields of immunology, gastrointestinal pathology, and microbiota–gut–brain axis research. Her early work focused on the phenotypic and functional characterization of innate immune components, particularly NK cells and macrophages, examining their role in tumor pathogenesis and their modulation by chemotherapeutic agents or plant-derived molecules. She later advanced her research to explore molecular and cellular mechanisms underlying major gastrointestinal diseases such as ischemia, intestinal inflammation, and enteric neuropathy, identifying the regulatory role of hyaluronic acid homeostasis in tissue repair. Her recent studies investigate gut microbiota, dysbiosis, and their influence on neurodevelopment and tumor etiopathogenesis, with growing emphasis on prebiotic and probiotic interventions. Dr. Bosi has contributed significantly to understanding experimental models of gut pathology, neuromuscular dysfunction, immunomodulation by virome components, and sex-dependent microbial effects. Her publications span high-impact journals, covering topics such as microbiota–immune interactions, ischemia–reperfusion injury, cytokine–phage crosstalk, and neuroimmune modulation. Through multidisciplinary approaches integrating molecular biology, immunology, and neurogastroenterology, her work continues to shape emerging perspectives on host–microbiota communication and its relevance to disease mechanisms and therapeutic strategies.

Profiles : Scopus | Orcid

Featured Publications

Bosi, A., Baranzini, N., Ponti, A., Moretto, P., Moro, E., Crema, F., Cianci, R., Karousou, E., Viola, M., Passi, A., et al. (2025). Intestinal ischemia/reperfusion injury influences hyaluronan homeostasis in the rat brain. International Journal of Molecular Sciences, 26(20), 10064.

Cianci, R., Caldarelli, M., Brani, P., Bosi, A., Ponti, A., Giaroni, C., & Baj, A. (2025). Cytokines meet phages: A revolutionary pathway to modulating immunity and microbial balance. Biomedicines, 13(5), 1202.

Faggin, S., Cerantola, S., Caputi, V., Tietto, A., Stocco, E., Bosi, A., Ponti, A., Bertazzo, A., Macchi, V., Porzionato, A., et al. (2025). Toll-like receptor 4 deficiency ameliorates experimental ileitis and enteric neuropathy: Involvement of nitrergic and 5-hydroxytryptaminergic neurotransmission. British Journal of Pharmacology, 182(8), 1803–1822.

Brani, P., Manzoor, H. Z., Spezia, P. G., Vigezzi, A., Ietto, G., Dalla Gasperina, D., Minosse, C., Bosi, A., Giaroni, C., Carcano, G., et al. (2025). Torque Teno Virus: Lights and shades. Viruses, 17(3), 334.

Dal Lago, S., Brani, P., Ietto, G., Dalla Gasperina, D., Gianfagna, F., Giaroni, C., Bosi, A., Drago Ferrante, F., Genoni, A., Manzoor, H. Z., et al. (2024). Torque Teno Virus: A promising biomarker in kidney transplant recipients. International Journal of Molecular Sciences, 25(14), 7744.

Giambra, V., Pagliari, D., Rio, P., Totti, B., Di Nunzio, C., Bosi, A., Giaroni, C., Gasbarrini, A., Gambassi, G., & Cianci, R. (2023). Gut microbiota, inflammatory bowel disease, and cancer: The role of guardians of innate immunity. Cells, 12(22), 2654.

Bosi, A., Banfi, D., Bistoletti, M., Catizzone, L. M., Chiaravalli, A. M., Moretto, P., Moro, E., Karousou, E., Viola, M., Giron, M. C., et al. (2022). Hyaluronan regulates neuronal and immune function in the rat small intestine and colonic microbiota after ischemic/reperfusion injury. Cells, 11(21), 3370.

Bosi, A., Banfi, D., Bistoletti, M., Moretto, P., Moro, E., Crema, F., Maggi, F., Karousou, E., Viola, M., Passi, A., et al. (2021). Hyaluronan: A neuroimmune modulator in the microbiota–gut axis. Cells, 11(1), 126.

Cerantola, S., Caputi, V., Contarini, G., Mereu, M., Bertazzo, A., Bosi, A., Banfi, D., Mantini, D., Giaroni, C., & Giron, M. C. (2021). Dopamine transporter genetic reduction induces morpho-functional changes in the enteric nervous system. Biomedicines, 9(5), 465.

Banfi, D., Moro, E., Bosi, A., Bistoletti, M., Cerantola, S., Crema, F., Maggi, F., Giron, M. C., Giaroni, C., & Baj, A. (2021). Impact of microbial metabolites on microbiota–gut–brain axis in inflammatory bowel disease. International Journal of Molecular Sciences, 22(4), 1623.

Baci, D., Bosi, A., Parisi, L., Buono, G., Mortara, L., Ambrosio, G., & Bruno, A. (2020). Innate immunity effector cells as inflammatory drivers of cardiac fibrosis. International Journal of Molecular Sciences, 21(19), 7165.

Baci, D., Bosi, A., Gallazzi, M., Rizzi, M., Noonan, D. M., Poggi, A., Bruno, A., & Mortara, L. (2020). The ovarian cancer tumor immune microenvironment (TIME) as target for therapy: A focus on innate immunity cells as therapeutic effectors. International Journal of Molecular Sciences, 21(9), 3125.

Bosi, A., Banfi, D., Bistoletti, M., Giaroni, C., & Baj, A. (2020). Tryptophan metabolites along the microbiota–gut–brain axis: An interkingdom communication system influencing the gut in health and disease. International Journal of Tryptophan Research, 13, 1–18.

Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Prof. Dr. Keon-Hyoung Song | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Soonchunhyang University | South Korea

Prof. Dr. Keon-Hyoung Song is a distinguished researcher whose work bridges pharmaceutical sciences, drug delivery systems, and pharmacokinetics. With 708 citations, 27 scholarly publications, and an h-index of 13, his research has significantly advanced the understanding of membrane permeation enhancers, drug formulation, and solubilization strategies. His extensive portfolio includes high-impact studies on intestinal absorption mechanisms, cocrystal engineering, and pharmacokinetic optimization, published in reputed journals such as Pharmaceutics, European Journal of Medicinal Chemistry, and Journal of Controlled Release. Prof. Song’s innovations extend beyond academia, with over 25 international patents registered across the U.S., Europe, and Korea, focusing on permeation-enhancing peptides, liposomal carriers, and pharmaceutical formulations. His pioneering patents, including those on mucous membrane permeation peptides (EP 3875103, 2025) and sugar alcohol-based liposome compositions, underscore his role in translating laboratory discoveries into therapeutic applications. Licensed as both a Patent Attorney and a Pharmacist, he effectively integrates regulatory insight with scientific innovation. Prof. Song’s sustained contributions to quantitative drug analysis using LC-MS and formulation optimization have made him a leading figure in advancing next-generation drug delivery technologies and pharmaceutical development.

Profile : Scopus

Featured Publications

Jeong, D.-H., Kim, J.-W., & Song, K.-H. (2025). Improved intestinal permeation of cyclosporin A by FCIGRL-modified tight junction modulator in rats. Pharmaceutics, 17(11), 1395.

Park, G., Galdamez, A., Song, K.-H., Le, M., Kim, K., & Lin, J. H. (2024). Ethnic variation and structure–function analysis of tauopathy-associated PERK alleles. Israel Journal of Chemistry, 64(12).

Song, K.-H. (2024). Effect of tight junction-modulating FCIGRL-modified peptides on the intestinal absorption of doxorubicin in rats. Pharmaceutics, 16(5), 650.

Jiang, F.-L., Jeong, D.-H., Eom, S.-H., Lee, H.-M., Cha, B.-J., Park, J.-S., Kwon, R.-K., Nam, J.-Y., Yu, H.-S., Heo, S.-H., Kim, C.-H., & Song, K.-H. (2024). Effects of enteric-coated formulation of sodium bicarbonate on bicarbonate absorption and gastrointestinal discomfort. Nutrients, 16(5), 744.

Koo, N. R., Yoon, S., Song, K.-H., Baek, M. J., Jeon, S., & Im, J. (2024). Tumor-homing peptide iRGD-conjugate enhances tumor accumulation of camptothecin for colon cancer therapy. European Journal of Medicinal Chemistry, 265, 116050.

Park, G., Xu, K., Chea, L., Kim, K., Safarta, L., Song, K.-H., Wu, J., Park, S., Min, H., Hiramatsu, N., Han, J., & Lin, J. H. (2023). Neurodegeneration risk factor EIF2AK3 (PERK) influences tau protein aggregation. The Journal of Biological Chemistry, 299(2), 102821.

Eom, Y. S., Jeong, D., Ryu, A.-R., Song, K.-H., Im, D. S., & Lee, M.-Y. (2022). Daphne odora exerts depigmenting effects via inhibiting CREB/MITF and activating AKT/ERK-signaling pathways. Current Issues in Molecular Biology, 44(8), 3312–3323.

Kim, H., Song, K.-H., Ambegaonkar, J. P., Chung, S., Jeon, K., Jiang, F. L., Eom, J. J., & Kim, C.-H. (2022). Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people. BMC Geriatrics, 22(1), 385.

Jiang, F., Tang, S., Eom, J.-J., Song, K.-H., Kim, H., Chung, S., & Kim, C.-H. (2022). Accuracy of estimated bioimpedance parameters with octapolar segmental bioimpedance analysis. Sensors, 22(7), 2681.

Yoon, Y. M., Lee, J. H., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins. Journal of Pineal Research, 68(3), e12632.

Lee, J. H., Yoon, Y. M., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. Aging Cell, 19(3), e13111.

Cha, S. J., Choi, H.-J., Kim, H.-J., Choi, E. J., Song, K.-H., Im, D. S., & Kim, K. (2020). Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. Insect Molecular Biology, 29(1), 56–65.*

Masroor Badshah | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Masroor Badshah | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Monash University | Australia

Author Profile

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Early Academic Pursuits

Dr. Masroor Badshah’s academic foundation is marked by a rigorous pursuit of medicine and anatomical sciences. Beginning with his degree in Medicine and Surgery, he developed an early research interest in the clinical relevance of anatomy, completing projects on skin diseases and vascular variations. His postgraduate studies at the University of Dundee expanded his expertise into human anatomy, where he defended a dissertation on carotid artery variations. This path led him to Monash University, where he earned his doctorate in medicine, focusing on oxytocin signaling in regulating the myogenic tone of the prostate and bladder. These early endeavors established a solid base for his later contributions to pharmacology and biomedical sciences.

Professional Endeavors

Dr. Badshah’s professional journey spans multiple countries, reflecting both versatility and international recognition. He began his teaching career as a lecturer and assistant professor in human anatomy at medical institutions in Pakistan before moving to Scotland and later Australia. His teaching associate roles at Monash University and research assistantship at the Monash Institute of Pharmaceutical Sciences allowed him to mentor students, design innovative teaching methodologies, and participate in collaborative research. His clinical internships in medicine and surgery also provided him with practical exposure that enriched his academic and research perspectives.

Contributions and Research Focus

At the core of Dr. Badshah’s career lies his dedication to advancing knowledge in pharmacology, toxicology, and pharmaceutical sciences. His doctoral work investigated the pharmacological role of oxytocin receptor antagonists in bladder and prostate function, with implications for overactive bladder treatments. His broader research includes studies in human surface anatomy, craniofacial asymmetry, morphometry of skeletal structures, and the clinical relevance of anatomical variations. By combining anatomical precision with pharmacological inquiry, he bridges the gap between foundational science and therapeutic application.

Accolades and Recognition

Throughout his career, Dr. Badshah has been honored with prestigious awards and scholarships, including the Monash Graduate Scholarship, Faculty International Tuition Scholarship, and the University of Dundee Tuition Scholarship. His academic excellence is reflected in multiple publications in peer-reviewed journals such as Biomedicines, Clinical Anatomy, and the Italian Journal of Anatomy and Embryology. He has also been a frequent presenter at international conferences, where his research findings on oxytocin signaling and anatomical morphometry have received recognition from the scientific community.

Impact and Influence

Dr. Badshah’s influence extends beyond research publications to shaping the next generation of medical and pharmaceutical scientists. His teaching philosophy emphasizes critical thinking, active participation, and evidence-based learning. By integrating innovative methodologies and fostering a collaborative learning environment, he has left a lasting impression on his students across different institutions. His work in surface anatomy and pharmacological sciences contributes to both clinical education and translational research, making his influence both academic and practical.

Legacy and Future Contributions

As a researcher with interdisciplinary expertise, Dr. Badshah’s legacy lies in his ability to merge anatomy with pharmacology for improved clinical outcomes. His ongoing research into bladder and prostate physiology offers potential breakthroughs in addressing urological disorders. Looking ahead, he aims to expand his collaborations globally, secure independent research leadership, and explore translational aspects of his work that could lead to therapeutic innovations. His legacy will continue to inspire young researchers and contribute to the evolution of biomedical sciences.

Publication


Investigating the Pharmacological Impact of Atosiban, an Oxytocin Receptor Antagonist, on Bladder and Prostate Contractions Within Obese and Non-Obese Rats
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Sarah M. Turpin-Nolan, Khaled A. Elnahriry, Ralf Middendorff, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2025


Age-Dependent Effects of Oxytocin and Oxytocin Receptor Antagonists on Bladder Contractions: Implications for the Treatment of Overactive Bladder Syndrome
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Ralf Middendorff, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2024


The Effects of Age on Prostatic Responses to Oxytocin and the Effects of Antagonists
Authors: Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Michael Whittaker, Betty Exintaris
Journal: Biomedicines
Year: 2023


Type of Treatment Supporters in Successful Completion of Tuberculosis Treatment: A Retrospective Cohort Study in Pakistan
Authors: Sana Hussain, Jamshed Hasnain, Zareen Hussain, Masroor Badshah, Hafeez Siddique, Christina Fiske, April Pettit
Journal: The Open Infectious Diseases Journal
Year: 2018


Morphology of the Human Hard Palate: A Study on Dry Skulls
Authors: Masroor Badshah, Roger Soames, Muhammad Jaffar Khan, Jamshaid Hasnain
Journal: Italian Journal of Anatomy and Embryology
Year: 2018


Conclusion

Dr. Masroor Badshah exemplifies the qualities of a dedicated academic, skilled researcher, and inspiring mentor. His career trajectory reflects a balance of teaching, research, and clinical exposure, with a focus on advancing pharmacology and anatomical sciences. His publications, conference presentations, and mentoring of students have strengthened his academic influence, while his research contributions offer practical applications in medicine. With a strong foundation and a vision for global collaboration, Dr. Badshah’s journey positions him as a leading figure in biomedical and pharmaceutical research, making his recognition as a distinguished researcher both timely and well-deserved.

Shahbaz Khan | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Shahbaz Khan | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Pharmacy Academy, Institute of Foreign Trade and Management University | India

Author Profile

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Early Academic Pursuits

Dr. Shahbaz Khan’s academic journey reflects a strong commitment to pharmaceutical sciences, beginning with foundational studies in pharmacy and advancing through specialized postgraduate training in pharmacology. His scholarly dedication culminated in a doctoral degree in pharmaceutical sciences, where his research explored the phytochemical and pharmacological activities of Betula alnoides bark extracts. These early academic achievements not only provided him with a robust understanding of pharmacological principles but also shaped his future research interests in neuropharmacology, neuroscience, and inflammation studies.

Professional Endeavors

Dr. Khan’s professional career spans diverse academic and administrative roles in reputed institutions. He has served as a faculty member in both assistant and associate professor capacities, mentoring students at undergraduate, postgraduate, and doctoral levels. Alongside his teaching and research responsibilities, he has contributed significantly to institutional development through administrative positions such as hostel warden. His teaching philosophy combines rigorous academic training with practical exposure, ensuring that his students are well-prepared for the pharmaceutical and healthcare industries.

Contributions and Research Focus

Dr. Khan’s research portfolio is extensive and multidisciplinary, with particular emphasis on neuropharmacology, phytochemistry, and inflammation-related pathologies. His studies delve into the therapeutic potential of medicinal plants, the development of advanced drug delivery systems, and the role of nutraceuticals in managing neurodegenerative and chronic diseases. His work also encompasses nanomedicine, regenerative medicine, and targeted therapies, leading to innovations in formulations and biomedical applications. By integrating modern pharmacological techniques with traditional medicinal knowledge, he has made meaningful contributions to both preclinical research and applied therapeutic strategies.

Accolades and Recognition

Dr. Khan has earned multiple national and international honors that recognize his academic excellence and research contributions. His achievements include prestigious travel grants for participating in global scientific programs organized by international brain research organizations, as well as awards for specialized training in molecular neuropharmacology. These recognitions underscore his role as a scholar of global repute and his ability to represent Indian pharmaceutical research on international platforms.

Impact and Influence

The impact of Dr. Khan’s work extends beyond his own research, influencing students, collaborators, and the broader scientific community. His publications in high-impact journals have contributed to advancing knowledge in pharmacology, medicinal chemistry, and biomedical sciences. His patents and innovations in pharmaceutical formulations highlight his ability to bridge the gap between laboratory research and practical healthcare solutions. Through book authorship and editorial contributions, he has also enriched the academic resources available to scholars worldwide.

Legacy and Future Contributions

Dr. Khan’s legacy lies in his ability to combine teaching, research, and innovation into a cohesive professional identity. His mentorship has guided many students toward successful careers in pharmacy and research. Looking ahead, he aims to expand his research in neurotherapeutics, nanomedicine, and herbal pharmacology, with a focus on developing novel, safe, and effective treatments for neurological and inflammatory disorders. His future contributions are expected to further strengthen the role of pharmaceutical sciences in addressing global health challenges.

Publications


Exploring Betula alnoides Bark: Insilico and Preclinical Insights into its Antioxidant and Lipid-Lowering Effects in Hypercholesterolemia
Authors: Shahbaz Khan, Alka Lohani, Prashant Tiwari, Sunil Kumar Kadiri
Journal: Obesity Medicine
Year: 2025


Innovative nanomedicine for fungal infections: Advancing treatments through nanotechnology and mycological approaches
Authors: Alka Lohani, Ritika Saxena, Shahbaz Khan, Ana Figueiras, Filipa Mascarenhas-Melo
Journal: Journal of Drug Delivery Science and Technology
Year: 2025


Tailored polymeric hydrogels for regenerative medicine and drug delivery: From material design to clinical applications
Authors: Alka Lohani, Ritika Saxena, Joana Galvão Duarte, Shahbaz Khan, Ana Figueiras, Filipa Mascarenhas-Melo
Journal: International Journal of Pharmaceutics
Year: 2025


pH-responsive IPN beads of carboxymethyl konjac glucomannan and sodium carboxymethyl cellulose as a controlled release carrier for ibuprofen
Authors: Alka Lohani, Ritika Saxena, Shahbaz Khan, Filipa Mascarenhas-Melo
Journal: International Journal of Biological Macromolecules
Year: 2024


An Insight Into Neuropathic Pain: A Systemic and Up-To-Date Review
Authors: Himanshu Sharma, Tanzeeb Rani, Shahbaz Khan
Journal: International Journal of Pharmaceutical Sciences and Research
Year: 2023


Conclusion

Through unwavering dedication to research, teaching, and innovation, Dr. Shahbaz Khan has established himself as a respected authority in pharmaceutical sciences. His contributions continue to inspire students, peers, and the scientific community at large, ensuring his place as a pivotal contributor to advancements in healthcare and pharmacology.

 

Yuanyuan Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Yuanyuan Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Guangdong Provincial Laboratory of Traditional Chinese Medicine | China

Author Profile

Scopus

🎓 Early Academic Pursuits

Dr. Li’s academic path began with an exceptional undergraduate performance in Chemistry at Jilin University. Her passion for science led her to pursue a Master’s degree in Analytical Chemistry and subsequently a Ph.D. in the same field, which she completed in July 2014 under the guidance of esteemed professor Zhang Shusheng. During her doctoral studies, she received comprehensive training in analytical techniques and developed a strong interest in practical applications related to food and environmental safety.

🏢 Professional Endeavors

In 2014, Dr. Li joined the School of Public Health at Jilin University as a faculty member. She steadily rose through the ranks to become a full professor and doctoral supervisor. Her responsibilities have included leading multiple high-level national projects, mentoring graduate students, and engaging in collaborative research across disciplines. She has become a pivotal figure in shaping the academic direction of the university’s public health research programs.

🔬 Contributions and Research Focus

Dr. Li’s research primarily focuses on food safety risk assessment, monitoring of toxic and hazardous substances in the food chain, and the development of advanced analytical methods. She has published over 80 high-impact academic papers, including articles in Analytical ChemistryBiosensors and BioelectronicsACS Sensors, and TrAC Trends in Analytical Chemistry. Her work integrates innovative electrochemical and optical biosensing techniques, making significant advancements in the detection of pesticide residues, foodborne pathogens, and environmental pollutants.

🏆 Accolades and Recognition

Her excellence has not gone unnoticed. Dr. Li has received several prestigious honors, including the “Young Elite Scientists Sponsorship Program” by the China Association for Science and Technology and the First Prize for Scientific and Technological Progress by the Jilin Provincial Government. She has also served as a visiting scholar at the University of Michigan, where she broadened her international research collaboration network.

🌍 Impact and Influence

Dr. Li's research has had a profound impact on public health, food regulation, and environmental policy. Her cutting-edge methodologies contribute directly to national standards and have been implemented in real-world food safety monitoring. She is also an active member of professional organizations and frequently serves as a reviewer for top-tier scientific journals, thereby shaping the future of analytical science and public health on both national and global scales.

🔮 Legacy and Future Contributions

Looking forward, Dr. Yuanyuan Li is poised to continue her groundbreaking work in biosensor development and integrated health risk assessment. Her vision is to establish more comprehensive detection platforms that can safeguard food and environmental quality, ultimately enhancing public health resilience. As a mentor, researcher, and innovator, her legacy is one of rigorous science combined with a deep commitment to societal well-being.

 

Publications


📄 Shenxiong Yixin Decoction polysaccharides exert therapeutic effects against myocardial ischemia-reperfusion injury via intestinal exosomal microRNA-21 regulation

Authors:
De-Sheng Xu, Yan Wang, Zi-Rui Li, Ping-Li Mo, Ming-Tai Chen, Rui-Zhi Zhao, Zheng Fan, Wen-Jie Mo, Qi-Lu Li, Fang-Cao Pi, Qi-Di Sun, Juan-Min Li, Yun-Da Yao, Jian-Ping Chen, Yuan-Yuan Li, Jie-Nan Luan, Shang-Bin Zhang, Ying Xie, Hua Zhou

Journal: Pharmacological Research   Year: 2025


📄 Syringic acid attenuates acute lung injury by modulating macrophage polarization in LPS-induced mice

Authors:
W.-T. Wang, Y.-Y. Zhang, Z.-R. Li, J.-M. Li, H.-S. Deng, Y.-Y. Li, H.-Y. Yang, C.-C. Lau, Y.-J. Yao, H.-D. Pan, L. Liu, Y. Xie, H. Zhou et al.

Journal: Phytomedicine   Year: 2024


📄 A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment

Authors:
M.-T. Chen, F.R. Huang, B.-H. Chen, J.-L. Kang, Y.-J. Yao, M.-N. Liu, Y.-Y. Li, Y.-Q. Li, T.-R. Zhou, D.-T. Peng, L.-D. Luo, C.-S. Wei, Y.-F. Xing, Q.-B. Wu, H. Zhou, G.-D. Tong

Journal: Biomedicine & Pharmacotherapy   Year: 2023

Ahmet Özdemir | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Prof Dr. Ahmet Özdemir | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Anadolu University | Turkey

Author Profile

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Orcid

Early Academic Pursuits 🎓

Prof. Dr. Ahmet Özdemir's academic journey began at Salihli Cumhuriyet Elementary School (1978-1983), followed by Salihli 50. Yıl Secondary School (1983-1986) and Salihli High School (1986-1989). His passion for pharmacy led him to Anadolu University Faculty of Pharmacy, where he completed his undergraduate studies (1990-1994). He pursued further education at the Graduate School of Health Sciences, Department of Pharmaceutical Chemistry at Anadolu University, earning a Master's degree (1995-1996) and a Doctor's degree (1996-2004).

Professional Endeavors 💼

Prof. Dr. Özdemir's professional career commenced at Anadolu University as a Research Assistant (1997-2004). He progressed to Research Assistant Doctor (2004-2005), Lecturer (2005-2007), and Assistant Professor Doctor (2007-2010). His dedication and expertise earned him the title of Associate Professor Doctor (2010-2015), and he has been serving as a Professor Doctor since 2015.

Contributions and Research Focus 🔍

Prof. Dr. Özdemir's research is marked by significant contributions to pharmaceutical chemistry. His Master's thesis focused on "The studies on the synthesis, structure elucidations and determination of physicochemical parameters of some 2-substituted-1H-phenantro[9,10-d]imidazole compounds," under the supervision of Prof. Dr. İlhan Işıkdağ. His PhD thesis, supervised by Prof. Dr. Gülhan Turan, investigated the "Synthesis of some 1-[(N,N-disubstituted-thiocarbonylthio)acetyl]-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and their antifungal, antibacterial activities."

Accolades and Recognition 🏅

Prof. Dr. Özdemir's work has been widely recognized, earning him numerous awards:

  • Anadolu University Article Performance Award (2014, 2016, 2017, 2018, 2020)
  • Anadolu University Gold Article Performance Award (2015)
  • Anadolu University Platinum Article Performance Award (2015)
  • Anadolu University Academic Success Award (2019)
  • ISIF'21 Silver Medal for the invention "Targeted Novel Triazolothiadiazine Derivatives for The Treatment of Lung Cancer" (2021)

Impact and Influence 🌟

Prof. Dr. Özdemir's impact extends beyond research. He has held key administrative roles, including Associate Director of Anadolu University Yunus Emre Vocational School (2011-2014) and Vice Academic Director of the Anadolu University Open Education Faculty, Department of Health Administration (2015-present). His mentorship has guided many students, as evidenced by his supervision of numerous master’s and doctoral dissertations.

Legacy and Future Contributions 🚀

Prof. Dr. Özdemir’s legacy is built on his unwavering commitment to advancing pharmaceutical chemistry. His innovative research, administrative leadership, and dedication to education have left an indelible mark on Anadolu University and the broader scientific community. As he continues his work, Prof. Dr. Özdemir is poised to make further groundbreaking contributions that will shape the future of pharmaceutical sciences.

 

Publications

📜Title: Design, Synthesis, and Biological Evaluation of a New Series of Imidazothiazole-Hydrazone Hybrids as Dual EGFR and Akt Inhibitors for NSCLC Therapy
Authors: Mehlika Dilek Altıntop, İpek Ertorun, Gülşen Akalın Çiftçi, Ahmet Özdemir
Journal: European Journal of Medicinal Chemistry
Year: 2024

📜Title: Design, Synthesis, and In Vivo Evaluation of a New Series of Indole-Chalcone Hybrids as Analgesic and Anti-Inflammatory Agents
Authors: Baramaki, I., Altıntop, M.D., Arslan, R., Hasan, A., Bektaş Türkmen, N.
Journal: ACS Omega
Year: 2024

📜Title: Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents
Authors: Altıntop, M.D., Cantürk, Z., Özdemir, A.
Journal: ACS Omega
Year: 2023

📜Title: Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy
Authors: Erdönmez, B., Altıntop, M.D., Akalın Çiftçi, G., Özdemir, A., Ece, A.
Journal: ACS Omega
Year: 2023

📜Title: A New Series of Hydrazones as Small-Molecule Aldose Reductase Inhibitors
Authors: Altıntop, M.D., Demir, Y., Türkeş, C., Beydemir, Ş., Özdemir, A.
Journal: Archiv der Pharmazie
Year: 2023

📜Title: A New Series of Thiazole-Hydrazone Hybrids for Akt-Targeted Therapy of Non-Small Cell Lung Cancer
Authors: Orujova, T., Ece, A., Akalın Çiftçi, G., Özdemir, A., Altıntop, M.D.
Journal: Drug Development Research
Year: 2023

Jiatong Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Assist Prof Dr. Jiatong Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Shanghai Jiao Tong University School of Medicine | China

Author Profile

Scopus

Early Academic Pursuits

Dr. Jiatong Li began her academic journey with a BA in Clinical Pharmacology at Harbin Medical University, followed by a PhD in Pharmacology under the mentorship of Prof. Bao-Feng Yang. She further honed her skills through an exchange program in Cellular Physiology at Okayama University, Japan.

Professional Endeavors

Joining Shanghai Jiao Tong University School of Medicine, Dr. Li delved into research focusing on novel antitumor therapeutics. She explored pharmacodynamics, drug actions, and underlying mechanisms, contributing significantly to the field.

Contributions and Research Focus

Dr. Li's research primarily revolves around synthesizing and applying six-membered aromatic nitrogen heterocyclic anti-tumor agents. She also investigated the suppression of hepatocellular carcinoma metastasis and cancer stem cell-like properties. Additionally, her work includes solvent-free and catalyst-free direct alkylation of alkenes.

Accolades and Recognition

Dr. Li's impactful research has earned her recognition in prestigious journals, with several publications featuring as cover stories. Her contributions have significantly advanced understanding in the field of pharmacology.

Impact and Influence

Through her research, Dr. Li has made a profound impact on the pharmacological community, shedding light on innovative therapeutic approaches and mechanisms underlying cancer progression.

Legacy and Future Contributions

Dr. Li's legacy lies in her groundbreaking research, which has paved the way for further advancements in antitumor therapeutics. Her future contributions are anticipated to continue shaping the landscape of pharmacology, with a focus on addressing critical challenges in cancer treatment.

Notable Publications

Pancreatic cancer environment: From patient-derived models to single-cell omics 2024

Six-Membered Aromatic Nitrogen Heterocyclic Anti-Tumor Agents: Synthesis and Applications 2023

Aggregation-enabled alkene insertion into carbon–halogen bonds 2023 (1)

Solvent-free and catalyst-free direct alkylation of alkenes 2023 (1)

Trisubstituted alkenes featuring aryl groups: stereoselective synthetic strategies and applications 2023 (3)

Simon Bernard Iloki Assanga | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Prof Dr. Simon Bernard Iloki Assanga | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

University of Sonora | Mexico

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Early Academic Pursuits

Dr. Simon Bernard Iloki Assanga embarked on his academic journey by obtaining a Bachelor's degree from the Pre-University Institute February 5 in Isle of Youth, Cuba, followed by a Graduate degree in Pharmaceutical Sciences from the University of Havana, Cuba. His academic pursuits culminated with a Doctorate in Pharmaceutical Sciences with a specialty in Immunology from the same institution in 2005.

Professional Endeavors

Dr. Assanga's professional career has been marked by a diverse array of roles, spanning from teaching to research. Noteworthy positions include his tenure as a Subject Teacher at the University of Sonora in Mexico, where he contributed to the Science department's Chemical-Biological sector. Additionally, he served as an Associate Full-Time Research Professor at the Department of Research and Postgraduate Studies in Food (DIPA) at the University of Sonora.

Contributions and Research Focus

Throughout his career, Dr. Assanga has made significant contributions to the field of pharmaceutical sciences and immunology. He has led various research projects, such as investigating the therapeutic potential of natural products for age-related macular degeneration and scaling up pilot plant production for nutraceuticals. His research interests also include exploring the chemical and nutritional composition of medicinal plants and their potential applications in healthcare.

Accolades and Recognition

Dr. Assanga's dedication and contributions have been recognized through numerous awards and honors. Notably, he received recognition for Outstanding Foreign Graduate from the Pharmacy Institute and Food at the University of Havana. He is also a member of prestigious scientific societies like the Society for Redox Biology and Medicine, highlighting his standing in the academic community.

Impact and Influence

Dr. Assanga's research, teaching, and participation in academic events have had a profound impact on the field of pharmaceutical sciences and immunology. His work in elucidating the therapeutic properties of natural products and mentoring students has contributed to advancements in healthcare and inspired future generations of researchers.

Legacy and Future Contributions

As a respected academic and researcher, Dr. Assanga's legacy lies in his extensive body of work, mentorship of aspiring scientists, and active participation in scientific discourse. His commitment to advancing knowledge in pharmaceutical sciences and immunology ensures that his contributions will continue to shape the field for years to come. In the future, he aims to further explore the therapeutic potential of natural products and collaborate on interdisciplinary research projects aimed at addressing pressing healthcare challenges.

Notable Publications

Targeting beta-catenin signaling for prevention of colorectal cancer – Nutraceutical, drug, and dietary options 2023

Nutraceutical and dietary resources for breast cancer prevention – Highlighting strategies for suppressing breast aromatase expression 2023 (1)

Nutraceuticals/Drugs Promoting Mitophagy and Mitochondrial Biogenesis May Combat the Mitochondrial Dysfunction Driving Progression of Dry Age-Related Macular Degeneration 2022 (10)

Targeting Sirt1, AMPK, Nrf2, CK2, and Soluble Guanylate Cyclase with Nutraceuticals: A Practical Strategy for Preserving Bone Mass 2022 (11)

Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity 2022 (20)

 

 

 

Assoc Prof Dr. Nicola Micale | Pharmacology, Toxicology and Pharmaceutical Science | Best Research Award

Assoc Prof Dr. Nicola Micale | Pharmacology, Toxicology and Pharmaceutical Science | Best Research Award

University of Messina | Italy

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Early Academic Pursuits

Associate Professor Dr. Nicola Micale commenced his academic journey with an exceptional focus on Chemistry and Pharmaceutical Technology, culminating in an honored degree from the University of Messina. This foundation laid the groundwork for his specialization in pharmacology and pharmaceutical sciences.

Professional Endeavors

Micale's career trajectory has been marked by a series of esteemed positions, from pivotal research roles to impactful lectureships across Europe. His academic pursuits have extended globally, emphasizing collaborative research ventures and immersive academic experiences.

Contributions and Research Focus

Central to Micale's contributions is his intensive focus on neurodegenerative disorders and innovative drug design. His research spans diverse areas, ranging from peptidomimetics to targeted drug development, showcasing a commitment to combatting microbial infections and malignancies.

Accolades and Recognition

Micale's exemplary research earned him notable recognition, including the Farmindustria Award for Pharmaceutical Research and invitations to deliver lectures at prestigious international conferences. These accolades affirm his expertise and contributions to the field.

Impact and Influence

Beyond his research contributions, Micale's influence is evident through his pivotal roles on the editorial boards of multiple international scientific journals. His role as a reviewer for esteemed publications underscores his commitment to shaping scholarly dialogue and validating scientific research.

Legacy and Future Contributions

Associate Professor Dr. Nicola Micale's legacy is rooted in his multidisciplinary approach to pharmaceutical sciences and his dedication to fostering global scientific collaborations. His ongoing contributions are poised to drive advancements in pharmaceutical research, leaving a lasting imprint on the field's progression and innovation.

Notable Publications

Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses 2023 (6)

Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 M pro 2023 (5)

Computational Design, Synthesis, and Biophysical Evaluation of β-Amido Boronic Acids as SARS-CoV-2 M pro Inhibitors 2023 (3)