Soonchunhyang University | South Korea
Prof. Dr. Keon-Hyoung Song is a distinguished researcher whose work bridges pharmaceutical sciences, drug delivery systems, and pharmacokinetics. With 708 citations, 27 scholarly publications, and an h-index of 13, his research has significantly advanced the understanding of membrane permeation enhancers, drug formulation, and solubilization strategies. His extensive portfolio includes high-impact studies on intestinal absorption mechanisms, cocrystal engineering, and pharmacokinetic optimization, published in reputed journals such as Pharmaceutics, European Journal of Medicinal Chemistry, and Journal of Controlled Release. Prof. Song’s innovations extend beyond academia, with over 25 international patents registered across the U.S., Europe, and Korea, focusing on permeation-enhancing peptides, liposomal carriers, and pharmaceutical formulations. His pioneering patents, including those on mucous membrane permeation peptides (EP 3875103, 2025) and sugar alcohol-based liposome compositions, underscore his role in translating laboratory discoveries into therapeutic applications. Licensed as both a Patent Attorney and a Pharmacist, he effectively integrates regulatory insight with scientific innovation. Prof. Song’s sustained contributions to quantitative drug analysis using LC-MS and formulation optimization have made him a leading figure in advancing next-generation drug delivery technologies and pharmaceutical development.
Profile : Scopus
Featured Publications
Jeong, D.-H., Kim, J.-W., & Song, K.-H. (2025). Improved intestinal permeation of cyclosporin A by FCIGRL-modified tight junction modulator in rats. Pharmaceutics, 17(11), 1395.
Park, G., Galdamez, A., Song, K.-H., Le, M., Kim, K., & Lin, J. H. (2024). Ethnic variation and structure–function analysis of tauopathy-associated PERK alleles. Israel Journal of Chemistry, 64(12).
Song, K.-H. (2024). Effect of tight junction-modulating FCIGRL-modified peptides on the intestinal absorption of doxorubicin in rats. Pharmaceutics, 16(5), 650.
Jiang, F.-L., Jeong, D.-H., Eom, S.-H., Lee, H.-M., Cha, B.-J., Park, J.-S., Kwon, R.-K., Nam, J.-Y., Yu, H.-S., Heo, S.-H., Kim, C.-H., & Song, K.-H. (2024). Effects of enteric-coated formulation of sodium bicarbonate on bicarbonate absorption and gastrointestinal discomfort. Nutrients, 16(5), 744.
Koo, N. R., Yoon, S., Song, K.-H., Baek, M. J., Jeon, S., & Im, J. (2024). Tumor-homing peptide iRGD-conjugate enhances tumor accumulation of camptothecin for colon cancer therapy. European Journal of Medicinal Chemistry, 265, 116050.
Park, G., Xu, K., Chea, L., Kim, K., Safarta, L., Song, K.-H., Wu, J., Park, S., Min, H., Hiramatsu, N., Han, J., & Lin, J. H. (2023). Neurodegeneration risk factor EIF2AK3 (PERK) influences tau protein aggregation. The Journal of Biological Chemistry, 299(2), 102821.
Eom, Y. S., Jeong, D., Ryu, A.-R., Song, K.-H., Im, D. S., & Lee, M.-Y. (2022). Daphne odora exerts depigmenting effects via inhibiting CREB/MITF and activating AKT/ERK-signaling pathways. Current Issues in Molecular Biology, 44(8), 3312–3323.
Kim, H., Song, K.-H., Ambegaonkar, J. P., Chung, S., Jeon, K., Jiang, F. L., Eom, J. J., & Kim, C.-H. (2022). Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people. BMC Geriatrics, 22(1), 385.
Jiang, F., Tang, S., Eom, J.-J., Song, K.-H., Kim, H., Chung, S., & Kim, C.-H. (2022). Accuracy of estimated bioimpedance parameters with octapolar segmental bioimpedance analysis. Sensors, 22(7), 2681.
Yoon, Y. M., Lee, J. H., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins. Journal of Pineal Research, 68(3), e12632.
Lee, J. H., Yoon, Y. M., Song, K.-H., Noh, H., & Lee, S. H. (2020). Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. Aging Cell, 19(3), e13111.
Cha, S. J., Choi, H.-J., Kim, H.-J., Choi, E. J., Song, K.-H., Im, D. S., & Kim, K. (2020). Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. Insect Molecular Biology, 29(1), 56–65.*