Peng Chen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Prof. Peng Chen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Qingdao University | China

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Early Academic Pursuits 🎓

Prof. Peng Chen's journey in medical research began with a strong foundation in clinical medicine and biomedical sciences. She earned her Bachelor of Medicine degree from Taishan Medical College (1999-2004), where she gained essential medical knowledge and clinical training. Her pursuit of advanced expertise led her to Capital University of Medical Sciences (2004-2007), where she obtained a Master of Science degree, focusing on medical research methodologies and specialized clinical studies. To further deepen her understanding and expertise, she pursued a Doctor of Medicine (2009-2012) at Qingdao University, refining her specialization in ophthalmology and regenerative medicine.

Professional Endeavors 🔬

After completing her master's degree, Prof. Chen embarked on her professional career at the Shandong Eye Institute (2007-2016), a renowned institution dedicated to ophthalmology research. During her tenure, she made significant contributions to vision sciences and ocular disease research, strengthening her expertise in eye-related disorders. In 2016, she transitioned to Qingdao University, where she currently serves as a leading researcher and faculty member. Her role at the university allows her to conduct cutting-edge research on ophthalmology and liver regeneration, mentor young medical scientists, and contribute to the advancement of medical science.

Contributions and Research Focus 🔍

Prof. Chen's research has significantly impacted liver regeneration, macrophage efferocytosis, and ophthalmology, particularly in understanding cellular mechanisms and disease pathophysiology. Some of her key contributions include:

  • Liver Regeneration and Macrophage Efferocytosis: Her recent studies have explored the NLRP3 inflammasome's role in constraining liver regeneration by impairing macrophage efferocytosis (Sci Adv., 2025). Additionally, she has investigated the role of Aquaporin-5 in facilitating liver regeneration via the ROS/GSDMD pathway (Cell Signal., 2025) and how extracellular vesicles containing GAS6 protect the liver from ischemia-reperfusion injury (Cell Death Discov., 2024).
  • Ophthalmology and Ocular Disease Research: She has studied the retinoic acid synthesis pathway in AQP5-deficient mice and its implications for dry eye disease (Invest Ophthalmol Vis Sci., 2024). Her research has also examined the regulation of axon guidance by Slit2 and Netrin-1 signaling in lacrimal gland development (Invest Ophthalmol Vis Sci., 2023).

Prof. Chen’s research not only deepens scientific knowledge in these areas but also paves the way for novel therapeutic strategies for liver and eye diseases.

Accolades and Recognition 🏆

Prof. Chen’s contributions to medical science have been widely recognized through prestigious research grants and peer-reviewed publications. She has received:

  • National Natural Science Foundation of China (2020-2023): RMB 550,000 for research on AQP5’s protective role in lens transparency through miRNA-mediated autophagy.
  • Shandong Provincial Natural Science Foundation (2018-2021): RMB 150,000 for the identification and functional study of Fuchs corneal endothelial dystrophy gene.

Her research has been featured in top-tier scientific journals, including Science Advances, Cell Signal, Cell Death Discovery, and Investigative Ophthalmology & Visual Science, reinforcing her status as a leading expert in regenerative medicine and ophthalmology.

Impact and Influence 🌍

Prof. Chen’s work bridges fundamental research and clinical applications, making a profound impact in both ophthalmology and liver disease treatment. Her findings on macrophage efferocytosis and aquaporins have opened new avenues for therapeutic interventions in liver regeneration, while her contributions to ocular disease mechanisms have enhanced the understanding of corneal and lacrimal gland pathophysiology.

Through her mentorship, collaborations, and academic contributions, she continues to shape the next generation of medical researchers and clinicians, strengthening Qingdao University’s reputation as a hub for medical research excellence.

Legacy and Future Contributions 🚀

With an established track record in liver regeneration and ophthalmic research, Prof. Peng Chen’s future contributions are expected to drive medical innovations in regenerative medicine and precision healthcare. Her work on cellular signaling pathways, extracellular vesicles, and aquaporins will likely inspire new therapeutic breakthroughs in both systemic and ocular diseases. As she continues to lead cutting-edge research, mentor young scientists, and contribute to transformative discoveries, Prof. Chen’s legacy will be one of scientific excellence, innovation, and meaningful impact on global healthcare.

Publications

  • 📄NLRP3 inflammasome constrains liver regeneration through impairing MerTK-mediated macrophage efferocytosis

    • Journal: Science Advances
    • Year: 2025
    • Authors: Wei S, Guan G, Luan X, Yu C, Miao L, Yuan X, Chen P*, Di G*

  • 📄Aquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway

    • Journal: Cell Signaling
    • Year: 2025
    • Authors: Li B, Di G, Ge H, Song P, Han W, Sun H, Wang D, Chen P*, Wang Y*

  • 📄Extracellular vesicles containing GAS6 protect the liver from ischemia-reperfusion injury by enhancing macrophage efferocytosis via MerTK-ERK-COX2 signaling

    • Journal: Cell Death Discovery
    • Year: 2024
    • Authors: Miao L, Yu C, Guan G, Luan X, Jin X, Pan M, Yang Y, Yan J, Chen P*, Di G*

  • 📄Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice

    • Journal: Investigative Ophthalmology & Visual Science
    • Year: 2024
    • Authors: Ge H, Di G, Li B, Han W, Song P, Han S, Wang D*, Chen P*

  • 📄Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice

    • Journal: Investigative Ophthalmology & Visual Science
    • Year: 2023
    • Authors: Bai Y, Di G, Ge H, Li B, Zhang K, Zhang D, Wang D*, Chen P*

 

Simeon Ikechukwu Egba | Biochemistry, Genetics and Molecular Biology | Editorial Board Member

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Dr. Simeon Ikechukwu Egba | Biochemistry, Genetics and Molecular Biology | Editorial Board Member

Kampala International University | Uganda

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Early Academic Pursuits 📚

Dr. Simeon Ikechukwu Egba’s academic journey began with his foundational education in Nigeria. After completing his secondary education at Community Secondary School, Eha-ohuala and Special Science School, Igbeagu, he pursued his undergraduate studies at the University of Nigeria, Nsukka, where he earned a Bachelor’s degree in Biochemistry in 2000. His academic curiosity and dedication to biochemistry led him to continue his studies at the same institution, earning a Master's degree in 2010 and later a Ph.D. in Biochemistry in 2014. His commitment to furthering his expertise in medical laboratory sciences was also demonstrated through studies at Nnamdi Azikiwe University Teaching Hospital-Nnewi.

Professional Endeavors 🏫

Dr. Egba's professional journey in academia spans over twelve years, during which he has held numerous positions that showcase his leadership and commitment to research and education. He has served as a lecturer in Biochemistry at various institutions, including Michael Okpara University of Agriculture, Umudike, and currently at Kampala International University, Uganda. His responsibilities have included teaching courses in biochemistry, overseeing laboratory sessions, and coordinating various academic functions such as the Student Industrial Work Experience Scheme (SIWES). Additionally, he has taken on key administrative roles, including being a member of the University Senate, and has led projects in research and curriculum development.

Contributions and Research Focus 🔬

Dr. Egba’s research interests are diverse and impactful, focusing on medical biochemistry, natural products, immune-modulation, endocrinology, and biochemical toxicology. His research has not only expanded the scientific understanding of these fields but has also contributed to real-world applications, such as exploring the immune-modulatory effects of herbal extracts and investigating glucose transport enhancement. He has made significant contributions to diabetes research, with several studies on anti-diabetic poly-herbal formulas. His scholarly work includes over 70 publications and successful supervision of 18 postgraduate students, many of whom have gone on to have successful academic careers.

Accolades and Recognition 🏅

Dr. Egba's academic excellence has earned him recognition within the scientific community. He has received multiple research grants, including those from the TETFUND, for projects that focus on diabetes and immunological responses. His dedication to his field is evident not only in his numerous publications but also in his role as a mentor, guiding over 150 undergraduate students through their research projects, many of whom have received scholarships to pursue postgraduate studies worldwide. Dr. Egba is an active member of the Nigerian Society of Biochemistry and Molecular Biology (NSBMB) and the Association of Medical Laboratory Scientists of Nigeria (AMLSN).

Impact and Influence 🌍

Dr. Egba’s impact extends beyond academia through his direct contributions to research and the development of future scholars. His research on the biochemical effects of natural products has influenced studies on immune-modulation and endocrinology, providing valuable insights into how natural compounds can influence human health. He has also played a pivotal role in improving the quality of laboratory practices and biochemistry education. His students, both undergraduate and postgraduate, continue to carry forward his legacy in research and academia, furthering his influence globally.

Legacy and Future Contributions 🌟

Dr. Egba’s future contributions are poised to further cement his legacy as a leading academic and researcher. His ongoing research projects aim to continue advancing the understanding of the biochemical pathways in diseases such as diabetes, and his work with poly-herbal formulations could have significant therapeutic implications. As he trains the next generation of biochemists and medical laboratory scientists, Dr. Egba’s influence will continue to shape the future of research and medical science, particularly in the fields of immunology and endocrinology.

Publication

  • 📜 Effects of exposure to volatile organic compounds (VOCs) content from paint on automobile paint workers in Nsukka, South Eastern Nigeria
    Authors: Ogbodo, J.O., Egba, S.I., Ogbodo, C.G., Onwurah, I.E., Njoku, O.U.
    Journal: Heliyon
    Year: 2024
  • 📜 Understanding apoptosis in sickle cell anemia patients: Mechanisms and implications
    Authors: Obeagu, E.I., Ubosi, N.I., Obeagu, G.U., Egba, S.I., Bluth, M.H.
    Journal: Medicine (United States)
    Year: 2024
  • 📜 Evaluation of fertility hormones and biochemical stress initiated by toxicant in diet prepared with fish smoked with polyethylene (plastic) materials as a fuel source
    Authors: Uhuo, E.N., Egba, S.I., Alaebo, P.O., Obike, C.A., Ede, I.S.
    Journal: Comparative Clinical Pathology
    Year: 2023
  • 📜 Antioxidative properties of Adansonia digitata L. (baobab) leaf extract exert protective effect on doxorubicin-induced cardiac toxicity in Wistar rats
    Authors: Uhuo, E.N., Egba, S.I., Nwuke, P.C., Obike, C.A., Kelechi, G.K.
    Journal: Clinical Nutrition Open Science
    Year: 2022
  • 📜 Renoprotective effects of Adansonia digitata leaf extract on renal function and histopathological changes in vancomycin-induced nephrotoxicity in Wistar rats
    Authors: Uhuo, E.N., Egba, S.I., Nwuke, P.N., Odinamadu, H.
    Journal: Comparative Clinical Pathology
    Year: 2022

 

Lidia Petrella | Agricultural and Biological Sciences |Best Researcher Award

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Dr. Lidia Petrella | Agricultural and Biological Sciences |Best Researcher Award

Dept. Biology University of Naples Federico II | Italy

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🌱 Early Academic Pursuits

Dr. Lidia Petrella's academic journey began with a Bachelor's degree in Biological Science from the University of Campania Luigi Vanvitelli, where she graduated with honors in 2019. Her early research focused on "Metabolic syndrome and mitochondrial dysfunction," demonstrating her interest in cellular and metabolic processes. She furthered her studies with a Master's degree in Nutrition Biology at the University of Naples Federico II, where her thesis explored the impact of dietary supplementation on metabolic and inflammatory status in obese mice. These foundational years were crucial in shaping her future focus on mitochondrial function and nutrition.

👩‍🔬 Professional Endeavors

Dr. Petrella’s professional career is marked by practical experience in diverse laboratory settings. Notably, her curricular internship at Petrillo Biomedical Laboratory allowed her to delve into clinical and microbiological biochemical analysis. Her voluntary internship at the University of Naples Federico II’s Department of Biology furthered her research into energy metabolism and mitochondrial bioenergetics. Most recently, in 2024, she conducted off-site research at the University of Udine, studying mitochondrial dynamics in brain and liver samples from autistic mice, a project that aligns with her ongoing PhD research.

📚 Contributions and Research Focus

Dr. Petrella’s research focuses on the intricate connections between mitochondrial function, nutrition, and metabolic health. Her PhD work at the University of Naples Federico II examines bioactive food components and their potential role in modulating mitochondrial function in autism spectrum disorders. Throughout her career, she has contributed to numerous conferences and publications, including studies on mitochondrial metabolism, neuroinflammation, and synaptic plasticity in animal models. Her work emphasizes the impact of nutrition and dietary components on metabolic diseases and mitochondrial dysfunction, particularly in relation to autism and obesity.

🏆 Accolades and Recognition

Dr. Petrella has consistently achieved academic excellence, earning honors such as "110/110 cum Laude" in both her Bachelor's and Master's degrees. Her research contributions have been recognized through participation in prestigious national and international conferences, including the Italian Society of Physiology (SIF) and the 7th CUCS Conference. Her publications in esteemed journals further underscore her growing influence in the fields of mitochondrial biology, nutrition, and metabolic research.

🌍 Impact and Influence

Dr. Petrella's work has the potential to impact various fields, including nutrition, physiology, and autism research. By exploring how dietary components affect mitochondrial function and metabolic processes, she contributes to a deeper understanding of how nutrition can modulate physiological and pathological conditions. Her research on mitochondrial dysfunction in autism spectrum disorders, for instance, opens new avenues for potential therapeutic interventions that target metabolic pathways.

🔮 Legacy and Future Contributions

As Dr. Petrella continues her PhD research, her work is poised to make significant contributions to the understanding of the relationship between nutrition, metabolism, and mitochondrial health. Her ongoing studies in mitochondrial function in autism may lead to breakthroughs in dietary-based therapeutic strategies, and her expertise in bioactive food components positions her as a key figure in the intersection of nutrition and metabolic health. Dr. Petrella’s academic journey and professional endeavors foreshadow a promising legacy in both scientific research and its practical applications in health and wellness.

 

Publications

  • 📓Goat Milk Supplementation Modulates the Mitochondrial Metabolic Flexibility and Orexin-A Levels Influencing the Inflammatory Pattern in Rats
    Journal: Antioxidants
    Year: 2024
    Authors: Lidia Petrella, Rita Polito, Angela Catapano, Antonella Santillo, Maria Giovanna Ciliberti, Agostino Carmelo Sevi, Antonietta Messina, Gina Cavaliere, Francesca Marino, Maria Grazia Polverino
  • 📓Crosstalk between Adipose Tissue and Hepatic Mitochondria in the Development of the Inflammation and Liver Injury during Ageing in High-Fat Diet Fed Rats
    Journal: International Journal of Molecular Sciences
    Year: 2023
    Authors: Gina Cavaliere, Angela Catapano, Gianfranca Trinchese, Federica Cimmino, Ciro Menale, Lidia Petrella, M.P. Mollica
  • 📓From Obesity-Induced Low-Grade Inflammation to Lipotoxicity and Mitochondrial Dysfunction: Altered Multi-Crosstalk between Adipose Tissue and Metabolically Active Organs
    Journal: Antioxidants
    Year: 2023
    Authors: Gina Cavaliere, Federica Cimmino, Gianfranca Trinchese, Angela Catapano, Lidia Petrella, Mario D'Angelo, Loredana Lucchin, M.P. Mollica
  • 📓Hepatocyte Aquaporins AQP8 and AQP9 Are Engaged in the Hepatic Lipid and Glucose Metabolism Modulating the Inflammatory and Redox State in Milk-Supplemented Rats
    Journal: Nutrients
    Year: 2023
    Authors: Gianfranca Trinchese, Pasquale Gena, Federica Cimmino, Gina Cavaliere, Carlo Fogliano, Salvatore Garra, Angela Catapano, Lidia Petrella, Stefano Di Chio, Brunella Avallone
  • 📓Impedance Analysis to Evaluate Nutritional Status in Physiological and Pathological Conditions
    Journal: Nutrients
    Year: 2023
    Authors: Angela Catapano, Gianfranca Trinchese, Federica Cimmino, Lidia Petrella, Mario D'Angelo, Giulia Di Maio, Marco Crispino, Gina Cavaliere, Michele Monda, M.P. Mollica