Ester Tellone | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

Prof. Ester Tellone | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

University of Messina | Italy

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🎓 Early Academic Pursuits

Prof. Ester Tellone began her academic journey with a degree in Biological Sciences (1989) from the University of Messina, graduating with highest honors (110/110 cum laude). She followed this with a second degree in Natural Sciences (1996), again with top marks and a thesis on hemoglobin function in dolphins. Her early research was focused on environmental and marine biology, including dystrophic crises in lake ecosystems.

👩‍🔬 Professional Endeavors

Prof. Tellone embarked on her academic career in 1990 as a Technical Officer at the University of Messina. In 2001, she was appointed as a confirmed researcher and later became an Associate Professor in Biochemistry (BIO/10) in 2018. Since January 2022, she holds the title of Full Professor in the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences at the University of Messina. She has taught various biochemistry courses at undergraduate and postgraduate levels and has been involved in curriculum development, Ph.D. supervision, and departmental governance.

🔬 Contributions and Research Focus

Prof. Tellone's research is centered on red blood cells (erythrocytes) as model systems. Key research themes include:

🧪 Red Blood Cells: Investigating erythrocytes as biosensors and drug delivery systems and exploring amyloid protein aggregation effects.

🧬 Hemoglobin Functionality: Analyzing structural-functional properties and oxygenation dynamics in hemoglobins.

🧫 Band 3 Protein Interactions: Studying its interplay with deoxyhemoglobin and glycolytic enzymes in metabolic regulation.

Her work employs advanced mathematical models and biochemical tools to unravel complex cellular mechanisms, especially oxidative stress, apoptosis, and environmental toxicity in marine and human systems.

🏆 Accolades and Recognition

Prof. Tellone’s excellence has been widely recognized:

🥇 She holds a National Scientific Qualification for Full Professor in General Biochemistry (BIO/10).

📚 She is the author of over 80 scientific articles indexed in Scopus/Web of Science and has contributed chapters to internationally published books.

🧑‍🏫 She has served as Scientific Coordinator for several major EU- and MIUR-funded projects, including INNOVAQUA, 4FRAILTY, ORTHO Line, and SAMOTHRACE.

She is a reviewer for high-impact journals such as Molecules, Journal of Functional Foods, and British Journal of Hematology, and serves on editorial boards of multiple international scientific journals.

🌍 Impact and Influence

Prof. Tellone’s research has made significant contributions in both basic and applied science:

🔬 Her studies on red blood cells and hemoglobin have advanced understanding of diseases like ALS, Alzheimer’s, and diabetes.

🌱 Her environmental research has influenced biotechnological innovations in aquaculture, marine biology, and environmental biosensors.

👩‍🎓 As a mentor and Ph.D. supervisor, she has nurtured the careers of numerous researchers and students in the field of biochemistry.

🌟 Legacy and Future Contributions

Prof. Ester Tellone is a recognized thought leader in red blood cell biochemistry, environmental toxicology, and oxidative stress. Her work bridges molecular biology, environmental sciences, and medical biochemistry, creating interdisciplinary solutions for modern scientific challenges. With her continued involvement in international projects, editorial activities, and mentoring, her influence is set to grow further, shaping the next generation of biochemists and biomedical researchers.

Publications


📄 Exploring Tumor Cell–Platelet Biochemical Interactions by Dielectric Measurements of Blood: A Potential Target for Tumor Detection and Staging
Journal: Biology
Year: 2025 
Authors: Annamaria Russo, Ester Tellone, Francesco Farsaci


📄 Crosstalk Between Sickle Cell Disease and Ferroptosis
Journal: International Journal of Molecular Sciences
Year: 2025 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Antonella Calderaro, Davide Barreca, Ester Tellone, Stefano Putaggio


📄 Emerging Ferroptosis Involvement in Amyotrophic Lateral Sclerosis Pathogenesis: Neuroprotective Activity of Polyphenols
Journal: Molecules
Year: 2025 
Authors: Annamaria Russo, Stefano Putaggio, Ester Tellone, Antonella Calderaro, Santa Cirmi, Giuseppina Laganà, Silvana Ficarra, Davide Barreca, Giuseppe Tancredi Patanè


📄 Epicatechin Influence on Biochemical Modification of Human Erythrocyte Metabolism and Membrane Integrity
Journal: International Journal of Molecular Sciences
Year: 2024 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Giuseppina Laganà, Santa Cirmi, Silvana Ficarra, Davide Barreca, Elena Giunta, Ester Tellone, Stefano Putaggio


📄 Canine and Human Red Blood Cells: Biochemical Mechanisms for the Control of Heat Dissipation
Journal: Stresses
Year: 2024 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Stefano Putaggio, Ester Tellone, Silvana Ficarra, Davide Barreca, Giuseppina Laganà


S. Azhagu Madhavan | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Dr. S. Azhagu Madhavan | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Saveetha University | India

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🎓 Early Academic Pursuits

Dr. S. Azhagu Madhavan’s academic journey is rooted deeply in the life sciences, with a steadfast commitment to zoology and biotechnology. He completed his B.Sc., M.Sc., and Ph.D. at the prestigious A.V.V.M. Sri Pushpam College, affiliated with Bharathidasan University, Tamil Nadu, India. His academic curiosity led him from foundational studies in zoology and biotechnology to advanced research, culminating in a doctoral thesis titled “Elucidating the Pharmacological Effect of Costus Spicatus Rhizome Extract in Streptozotocin Induced Diabetic Albino Wistar Rats.” 🧪🧬 His early academic work also explored microbial biodiversity within earthworm guts, revealing his interest in both macro and micro life sciences.

🧑‍🔬 Professional Endeavors

With nearly five years of experience in academia and research, Dr. Madhavan has been shaping the minds of future scientists. He currently serves as an Assistant Professor at Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai. Prior to this, he honed his research skills as a Research Associate at Global Scientific Research Services and as a Research Assistant at Harman Institute of Science Education and Research. His journey reflects a blend of academic rigor and practical experience, contributing meaningfully to the scientific community.

🔍 Contributions and Research Focus

Dr. Madhavan’s research encompasses a wide range of cutting-edge disciplines including pharmacology, phytochemistry, nanobiotechnology, pharmaceuticals, and agricultural entomology. His scholarly efforts have led to impactful discoveries, especially in the synthesis and application of bioactive compounds and nanomaterials. His work on silver nanoparticles, biomarkers in autoimmune and neurological disorders, and natural therapeutic agents stands out for its translational value in modern medicine. His diverse research interests continue to evolve with interdisciplinary collaborations.

🏆 Accolades and Recognition

Dr. Madhavan’s academic brilliance has not gone unnoticed. In 2020, he was honored with the International Young Scientist Award at the 7th International Scientist Awards on Engineering, Science, and Medicine by VDGOOD Professional Association. He has also been recognized at several national conferences for his innovative contributions and oral presentations, including awards for his early research on earthworm-associated microbiota. His invited talks and memberships in peer-reviewed scholarly publishing forums further validate his scientific excellence.

🌍 Impact and Influence

Dr. Madhavan has made a global impact through his research, with multiple Q1 journal publications in top-tier platforms like Elsevier, Springer, and the Royal Society of Chemistry. His work has contributed to our understanding of nanomedicine, immunology, forensic neuroscience, and plant-based bioactive therapies, gaining recognition from peers worldwide. His designs, patented under the Indian IPR system, including innovations like biosensors, UV chambers, and biodegradable delivery systems, are already making waves in health tech and agriculture.

🌟 Legacy and Future Contributions

Dr. Madhavan is poised to leave a lasting legacy in biomedical and biotechnological research. His future plans likely include expanding interdisciplinary research, mentoring young scientists, and driving innovation through sustainable and impactful science. His visionary approach—combining traditional knowledge with modern scientific tools like nanotechnology and pharmacogenomics—positions him as a transformative figure in life sciences. As a passionate educator and a dynamic researcher, his contributions will continue shaping science and society.

Publications


📄 Identification and characterization of silver nanoparticles from Erythrina indica and its antioxidant and Uropathogenic antimicrobial properties
Authors: Sivalingam, Azhagu Madhavan; Pandian, Arjun
Journal: Microbial Pathogenesis
Year: 2024


📄 Exosomes in Regulating miRNAs for Biomarkers of Neurodegenerative Disorders
Authors: Sivalingam, Azhagu Madhavan; Sureshkumar, Darshitha D.
Journal: Molecular Neurobiology
Year: 2025


📄 Fungal pretreatment methods for organic wastes: advances and challenges in biomass valorization
Authors: Chaurasia, P.K.; Bharati, S.L.; Singh, S.; Sivalingam, A.M.; Shankar, S.; Mani, A.
Journal: RSC Sustainability
Year: 2025


📄 Antihyperglycemic Activity of Polyphenolic Metabolites and Biosynthesized Silver Nanoparticles from Pedalium murex: Characterization and Application of Antioxidant and Uropathogenic Antimicrobial Activities
Authors: Azhagu Madhavan Sivalingam; Arjun Pandian
Journal: Microbial Pathogenesis
Year: 2025


📄 Cerebellar pathology in forensic and clinical neuroscience
Authors: Azhagu Madhavan Sivalingam; Darshitha D. Sureshkumar; Vijayalakshmi Pandurangan
Journal: Ageing Research Reviews
Year: 2025


Kercia Cruz | Agricultural and Biological Sciences | Best Researcher Award

Dr. Kercia Cruz | Agricultural and Biological Sciences | Best Researcher Award

Federal University of Bahia | Brazil

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Early Academic Pursuits 🎓

Dr. Kercia Cruz began her academic journey with a degree in Biological Sciences from Universidade Federal da Bahia in 2014. She furthered her studies with a master’s in Biotechnology in Health and Investigative Medicine from Fundação Oswaldo Cruz, graduating in 2017. Her research during this period focused on leishmaniasis and the role of macrophages in infection. She then pursued a Ph.D. in Biotechnology in Health and Investigative Medicine at Fundação Oswaldo Cruz, completing it in 2023. Her doctoral research centered on the development of nanomedicines for treating leishmaniasis, particularly focusing on the protein translocator HSP90.

Professional Endeavors 🔬

Dr. Cruz has worked extensively in the field of general biology with a specialization in leishmaniasis and macrophage infections. Her professional experience includes positions at Universidade Federal da Bahia and Centro Universitário SENAI CIMATEC, where she has contributed significantly to research and education. Her roles involved working on projects related to the therapeutic potential of nanoparticles and the molecular mechanisms of leishmaniasis. She has also participated in various internships and short-term research activities across Brazil and Portugal. 🌍

Contributions and Research Focus 🧫

Dr. Cruz’s research primarily focuses on leishmaniasis, particularly the use of nanomedicines and the role of protein translocators like HSP90 in combating infection. She has been involved in several research projects exploring the potential of nanoparticle-based therapies for leishmaniasis and other infectious diseases. Her work also includes studying the molecular and cellular aspects of macrophage interactions with pathogens, contributing to the development of innovative treatment strategies. 🧪

Accolades and Recognition 🏅

Dr. Cruz has received notable recognition for her research contributions. In 2022, she was awarded an honorable mention for her work on polymeric nanoparticles containing amphotericin B at Embrapa. Additionally, she received a commendation in 2020 for her ongoing doctoral thesis from the Program of Postgraduate Studies in Biotechnology in Health and Investigative Medicine at Fiocruz. These accolades highlight her significant impact in her field. 🏆

Impact and Influence 🌟

Dr. Cruz’s research has advanced the understanding of leishmaniasis and the potential of nanomedicines in treating this disease. Her work on nanomedicine and protein translocators has provided valuable insights into innovative treatment approaches, potentially improving patient outcomes and contributing to global health solutions. Her contributions have influenced both academic research and practical applications in biotechnology. 🌐

Legacy and Future Contributions 🚀

Looking forward, Dr. Cruz aims to continue her work on developing novel therapeutic strategies for infectious diseases. Her future research will likely focus on expanding the use of nanomedicines and exploring new avenues in molecular biology to address pressing health challenges. Her dedication to advancing scientific knowledge and improving treatment options ensures that her legacy will continue to benefit the field of biotechnology and beyond.

 

Publications 📚


  • 📝Intraperitoneal Administration of 17-DMAG as an Effective Treatment against Leishmania braziliensis Infection in BALB/c Mice: A Preclinical Study
    • Authors: Kercia P. Cruz, Antonio L. O. A. Petersen, Marina F. Amorim, Alan G. S. F. Pinho, Luana C. Palma, Diana A. S. Dantas, Mariana R. G. Silveira, Carine S. A. Silva, Ana Luiza J. Cordeiro, Izabella G. Oliveira, Gabriella B. Pita, Bianca C. A. Souza, Gilberto C. Bomfim, Cláudia I. Brodskyn, Deborah B. M. Fraga, Isadora S. Lima, Maria B. R. De_Santana, Helena M. P. Teixeira, Juliana P. B. De_Menezes, Washington L. C. Santos
    • Journal: Pathogens
    • Year: 2024

  • 📝Development and Characterization of PLGA Nanoparticles Containing 17-DMAG, an Hsp90 Inhibitor
    • Authors: Kercia P. Cruz, Beatriz F. C. Patricio, Vinícius C. Pires, Marina F. Amorim, Alan G. S. F. Pinho, Helenita C. Quadros, Diana A. S. Dantas, Marcelo H. C. Chaves, Fabio R. Formiga, Helvécio V. A. Rocha, Patrícia S. T. Veras
    • Journal: Frontiers in Chemistry
    • Year: 2021

  • 📝Microbiologia no cotidiano: proposta de ensino por investigação de baixo custo
    • Authors: K. P. Cruz, G. L. Nery, A. A. D. Reboucás, P. R. Dantas-Silva, J. S. Cruz, C. G. S. Andrade, R. M. L. Rahimy
    • Journal: Atas de Ciências da Saúde
    • Year: 2019

  • 📝In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
    • Authors: C. E. S. Guedes, B. R. S. Dias, A. L. O. A. Petersen, Kercia P. Cruz, N. J. Almeida, D. R. Andrade, J. P. B. Menezes, V. M. Borges, P. S. T. Veras
    • Journal: Memórias do Instituto Oswaldo Cruz
    • Year: 2018

 

 

Guangqing Yu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Dr. Guangqing Yu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Henan Agricultural University | China

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Early Academic Pursuits

Dr. Guangqing Yu began her academic journey at Henan Normal University, where she majored in aquaculture and earned a bachelor's degree in agriculture. Her interest in genetics led him to pursue a Ph.D. at the Institute of Hydrobiology, Chinese Academy of Sciences. Here, she specialized in genetics, focusing on the mechanisms of fish immune and developmental responses, laying a strong foundation for her future research.

Professional Endeavors

As an Associate Professor at Henan Agricultural University, Dr. Yu has been actively involved in both teaching and research. Her professional endeavors are marked by her leadership in various research projects, including the National Natural Science Foundation of China Youth Project and the China Postdoctoral Science Foundation's general project. She has successfully secured funding for these projects, emphasizing her capability to lead significant research initiatives.

Contributions and Research Focus

Dr. Yu's research primarily uses zebrafish as a model organism to investigate the molecular mechanisms of fish immune responses and development. Her notable contributions include elucidating the role of epigenetic modifications in fish innate immunity against viruses and embryonic development. She has also studied the biological functions of NEDD8 and its impact on the development of ovaries and secondary sexual characteristics in zebrafish. Her findings have been published in prestigious journals such as Development, Journal of Immunology, and Frontiers in Immunology.

Accolades and Recognition

Dr. Yu's work has garnered recognition in the scientific community. Her research on NEDD8 and its enhancement of Hippo signaling by mediating YAP1 neddylation has been highly  respected. Additionally, her participation in the Major Research Program of the National Natural Science Foundation of China further underscores her contributions to the field.

Impact and Influence

Dr. Yu's research has significantly advanced the understanding of genetic and molecular mechanisms in fish. Her work on epigenetic modifications and their roles in immunity and development has broad implications, influencing both academic research and practical applications in aquaculture and fisheries management. Her studies on NEDD8 and androgen receptor hyperactivation have opened new avenues for understanding genetic regulation in vertebrates.

Legacy and Future Contributions

Dr. Yu's ongoing research projects and her active role in national research programs highlight her dedication to advancing the field of genetics. With multiple patents in process and numerous publications in high-impact journals, she continues to make significant contributions to molecular biology and genetics. Her future work is expected to further elucidate the complex mechanisms underlying fish biology, impacting both theoretical knowledge and practical applications.

Notable Publications

NEDD8 enhances Hippo signaling by mediating YAP1 neddylation 2024

Zebrafish spop promotes ubiquitination and degradation of mavs to suppress antiviral response via the lysosomal pathway 2024 (1)

Deletion of prolyl hydroxylase domain-containing enzyme 3 (phd3) in zebrafish facilitates hypoxia tolerance 2023 (1)