Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Dr. Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Pusan national university | South Korea

Author Profile

Orcid

πŸŽ“ Early Academic Pursuits

Dr. Dong Hee Kim began his academic journey with a Bachelor of Science in Biology from the University of Ulsan, Korea, in 2004. He continued at the same institution for his M.S.-Ph.D. in Biological Sciences under the mentorship of Professor Byung Ju Lee, completing his doctorate in 2012. His thesis, "Studies on the role of NELL2 in neuroprotection and neural differentiation," laid the foundation for his future research endeavors.

πŸ’Ό Professional Endeavors

Dr. Kim has held various prestigious positions throughout his career. He is currently a Research Fellow at Pusan National University Hospital since November 2022. Previously, he served as a Research Professor at the University of Ulsan from January 2019 to May 2022, and as a Research Fellow at the same university from January 2015 to October 2016. His early postdoctoral work was conducted at UNIST from March 2013 to December 2014.

πŸ§ͺ Contributions and Research Focus

Dr. Kim's research primarily revolves around neuroprotection, neural differentiation, and the molecular mechanisms underlying neurodegenerative diseases. His notable grants include funding from WISET for studying the function of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the brain, and multiple grants from the NRF of Korea, including studies on TonEBP function in hypothalamic leptin resistance and its role in degenerative brain disorders.

πŸ… Accolades and Recognition

Throughout his career, Dr. Kim has received significant recognition for his contributions to biomedical research. His projects have been supported by prestigious grants, highlighting the impact and importance of his work in understanding brain functions and disorders. His research has also resulted in numerous publications in high-impact journals, further establishing his reputation in the field.

🌟 Impact and Influence

Dr. Kim's research has significantly advanced the understanding of neural mechanisms and their implications in neurodegenerative diseases. His work on the transcription regulation of key genes involved in brain function and inflammation has provided new insights into potential therapeutic targets. His publications have been widely cited, indicating the influence of his research on the scientific community.

πŸ“š Legacy and Future Contributions

Dr. Kim's ongoing research continues to push the boundaries of our understanding of the brain. His current projects, funded by substantial grants, promise to uncover new mechanisms of brain function and disease. As he progresses in his career, Dr. Kim is poised to make further groundbreaking discoveries that will contribute to the field of biomedical science and technology.

 

Publications πŸ“˜

πŸ“„ Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Transcription Regulation of AgRP and POMC Genes

πŸ‘©β€πŸ”¬ Authors: Kim DH*, Lee MJ, Kang D, Khang AR, Bae JH, Kim JY, Kim SH, Kang YH, Yi D.

πŸ“• Journal: Curr Issues Mol Biol.

πŸ“… Year: 2024


πŸ“„ Bridging Energy Need and Feeding Behavior: The Impact of eIF2Ξ± Phosphorylation in AgRP Neurons

πŸ‘©β€πŸ”¬ Authors: Kim KK, Lee TH, Park BS, Kang D, Kim DH, Jeong B, Kim JW, Yang HR, Kim HR, Jin S, Back SH, Park JW, Kim JG, Lee BJ.

πŸ“• Journal: Diabetes

πŸ“… Year: 2023


πŸ“„ Sirtuin 1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to Energy Deficiency Response

πŸ‘©β€πŸ”¬ Authors: Kang D, Yang HR, Kim DH, Kim KK, Jeong B, Park BS, Park JW, Kim JG, Lee BJ.

πŸ“• Journal: Int J Mol Sci.

πŸ“… Year: 2023


πŸ“„ Inhibition of LPAR1 Signaling in PDLSCs Reduces the Inflammatory Paracrine Effect on Primary Astrocyte Cells

πŸ‘©β€πŸ”¬ Authors: Kim DH*, Seo EJ*, Kim YH, Jang IH.

πŸ“• Journal: Int J Oral Biol.

πŸ“… Year: 2022


πŸ“„ Transcriptional Regulatory Role of NELL2 in Preproenkphalin Gene Expression

πŸ‘©β€πŸ”¬ Authors: Ha CM*, Kim DH*, Lee TH, Kim HR, Choi JI, Kim Y, Kang DS, Park JW, Oieda S, Jeong JK, Lee BJ.

πŸ“• Journal: Mol Cells

πŸ“… Year: 2022

Cheng Li | Agricultural and Biological Sciences | Best Researcher Award

Dr. Cheng Li | Agricultural and Biological Sciences | Best Researcher Award

Massachusetts Institute of Technology | United States

Author Profile

Scopus

Early Academic Pursuits

Dr. Cheng Li began his academic journey with a Bachelor of Engineering from the South China University of Technology in Guangzhou, China. His passion for biotechnology and biochemical engineering led him to pursue advanced studies at the Massachusetts Institute of Technology (MIT) in Cambridge, US, where he completed his Ph.D. in 2018. During his doctoral studies, Dr. Li focused on metabolic engineering and synthetic biology, laying a strong foundation for his future research endeavors.

Professional Endeavors

Following his Ph.D., Dr. Li embarked on a series of postdoctoral research positions. He first served as a Postdoctoral Associate at the Singapore-MIT Alliance for Research and Technology from September 2018 to March 2021. Subsequently, he continued his postdoctoral research at MIT until March 2022. His work during these years was pivotal in advancing his expertise in microbial biotechnology and metabolic engineering. In April 2022, Dr. Li was appointed as a Research Scientist at MIT, where he continues to contribute to cutting-edge research.

Contributions and Research Focus

Dr. Li's research primarily revolves around the engineering of microorganisms for the production of valuable biochemical compounds. His notable contributions include optimizing the heterologous production of Ξ±-carotene in Corynebacterium glutamicum, developing modular engineering techniques for microbial production of carotenoids, and improving recombineering techniques in Corynebacterium glutamicum. Additionally, he has explored the recycling of selectable markers in Pichia pastoris and engineered phytase expression for potential use as a feed supplement.

Accolades and Recognition

Dr. Li's work has garnered significant recognition in the scientific community. He has published extensively in high-impact journals, showcasing his innovative research in metabolic engineering and synthetic biology. Some of his prominent publications include works in Metabolic Engineering, Bioresource Technology, Biotechnology and Bioengineering, and Scientific Reports. His research on engineering carbon source division of labor for efficient Ξ±-carotene production in Corynebacterium glutamicum is particularly noteworthy.

Impact and Influence

Dr. Li's research has made substantial contributions to the field of biotechnology, particularly in the areas of metabolic engineering and synthetic biology. His innovative approaches to microbial engineering have potential applications in the production of pharmaceuticals, biofuels, and other valuable biochemicals. By advancing the efficiency and scalability of these processes, Dr. Li's work supports the development of sustainable biotechnological solutions.

Legacy and Future Contributions

As a Research Scientist at MIT, Dr. Li continues to push the boundaries of microbial biotechnology. His ongoing research aims to further refine and optimize the production of high-value compounds through microbial engineering. By mentoring the next generation of scientists and collaborating with industry partners, Dr. Li is poised to make lasting contributions to the field. His work not only addresses current scientific challenges but also paves the way for future innovations in biotechnology and synthetic biology.

 

Notable Publications

Engineering carbon source division of labor for efficient Ξ±-carotene production inΒ Corynebacterium glutamicum 2024

Systems metabolic engineering ofΒ Corynebacterium glutamicum to assimilate formic acid for biomass accumulation and succinic acid production 2024

Expanding the CRISPR Toolbox for Engineering Lycopene Biosynthesis in Corynebacterium glutamicum 2024

EngineeringΒ Corynebacterium glutamicum for efficient production of succinic acid from corn stover pretreated by concentrated-alkali under steam-assistant conditions 2023 (7)

Overproduction of Patchoulol in Metabolically Engineered Komagataella phaffii 2023 (7)