Saint Louis University | United States
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🎓 Early Academic Pursuits
Dr. M. Abdul Mottaleb's academic journey is a testament to his dedication to scientific excellence. He obtained his Ph.D. in Analytical Chemistry and Environmental Sciences from the University of Strathclyde, Glasgow, UK (1992–1996). Prior to this, he earned an M.S. in Applied Chemistry with Chemical Engineering (1986–1988) and a B.S. in Applied Chemistry (1980–1986) from the University of Rajshahi, Bangladesh. His academic foundation in chemistry and environmental sciences laid the groundwork for his impactful research and professional contributions.
🌟 Professional Endeavors
Dr. Mottaleb has had an illustrious career spanning several esteemed institutions and research centers worldwide. Currently, he serves as a Senior Analytical Chemist (Associate Professor) at the Institute for Drug & Biotherapeutics Innovation, Doisy Research Center, Saint Louis University School of Medicine, Missouri, since 2020. Previously, he was an Assistant Professor and co-leader of the analytical mass spectrometry core facility at the University of Kentucky College of Medicine (2017–2020). His experience includes roles at Baylor University, the U.S. Environmental Protection Agency (EPA), Dongduk Women’s University in South Korea, and the University of Rajshahi, among others. His career reflects a strong commitment to scientific research, education, and environmental safety.
🔬 Contributions and Research Focus
Dr. Mottaleb’s research has significantly advanced analytical chemistry, particularly in mass spectrometry and environmental sciences. His expertise encompasses:
- Analytical method development, validation, and ADME/PK studies for drug discovery using UPLC-MS/MS and GC-MS/MS.
- Characterization and detection of per- and polyfluoroalkyl substances (PFAS), phthalates, disinfectant byproducts, and pharmaceutical contaminants in biological and environmental samples.
- Studies on bioavailability of trace toxic metals in seafood and soil contamination analysis.
- Development of mass spectrometric techniques for emerging contaminants in fish, aquatic organisms, and water compartments. His research has had a profound impact on environmental toxicology, public health, and pharmaceutical sciences.
🏆 Accolades and Recognition
Dr. Mottaleb's outstanding contributions have been recognized with numerous prestigious awards and fellowships:
- Merit Award (MA) by the American Chemical Society (2014).
- Scientific and Technological Achievement Award (STAA) by the U.S. EPA (2005).
- Science Achievement Award (SAA) in Chemistry by the U.S. EPA & American Chemical Society (2005).
- EPA-NRC Award (2001), KOSEF Fellowships (2000), and multiple merit scholarships.
- Chancellor Award (1987) from Bangladesh Universities. His membership in leading scientific organizations such as the American Chemical Society and the American Society for Mass Spectrometry highlights his dedication to scientific collaboration.
📝 Impact and Influence
Dr. Mottaleb’s research has garnered significant media attention, influencing policy discussions and public awareness of environmental contaminants. His work has been featured in Discovery Channel, MSNBC, LA Times, and National News. One of his widely recognized studies examined pharmaceutical contaminants in fish, highlighting the environmental impact of personal care products and drugs in aquatic ecosystems.
🌐 Legacy and Future Contributions
With over 80 peer-reviewed publications, Dr. Mottaleb continues to contribute groundbreaking research in analytical and environmental chemistry. His legacy includes mentoring young scientists, leading innovative research projects, and improving analytical methodologies for global environmental health. His future work is poised to further enhance drug discovery, environmental safety, and analytical chemistry techniques, ensuring his lasting impact on scientific advancements. Dr. M. Abdul Mottaleb’s career exemplifies scientific excellence, dedication to environmental health, and a commitment to fostering the next generation of researchers. His work remains invaluable in the fields of analytical chemistry and environmental sciences.
Publications
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📄 Improved analytical method for analysis of toxic/heavy metals in Fish by Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES)
Authors: Hind Msellek, Daniel R Johnson, Musavvir Arafat Mottaleb, Mohammed J. Meziani, M. Abdul Mottaleb
Journal: Food and Humanity
Year: 2025
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📄 Efficacy and in vitro pharmacological assessment of novel N-hydroxypyridinediones as hepatitis B virus ribonuclease H inhibitors
Authors: Molly E. Woodson, Holly F. Walden, Mohammad Abdul Mottaleb, Grigoris Zoidis, John E. Tavis
Journal: Antimicrobial Agents and Chemotherapy
Year: 2025
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📄 In vitro evaluation of tropolone absorption, metabolism, and clearance
Authors: Molly E. Woodson, Mohammad Abdul Mottaleb, Ryan P. Murelli, John E. Tavis
Journal: Antiviral Research
Year: 2023
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📄 Combined application of biosponges and an antifibrotic agent for the treatment of volumetric muscle loss
Authors: Charles West, Connor Tobo, Jeffrey Au, David W. Griggs, Koyal Garg
Journal: American Journal of Physiology - Cell Physiology
Year: 2023
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📄 Effect of lifestyle-based lipid-lowering interventions on the relationship between circulating levels of per-and polyfluoroalkyl substances and serum cholesterol
Authors: Stephanie Morgan, Mohammad Abdul Mottaleb, Maria P. Kraemer, Andrew J. Morris, Michael C. Petriello
Journal: Environmental Toxicology and Pharmacology
Year: 2023