Cleveland Clinic | United States

Author Profile

Early Academic Pursuits 🎓

Dr. Vishal Srivastava’s journey in academia began with a strong foundation in his chosen field of study. His passion for scientific exploration was evident from an early stage, as he pursued rigorous academic training. Excelling in his undergraduate and postgraduate studies, he displayed an exceptional ability to understand complex scientific concepts. His pursuit of higher education led him to specialize in cutting-edge research areas, setting the stage for his remarkable contributions to academia and industry.

Professional Endeavors 💼

With a solid academic background, Dr. Vishal Srivastava embarked on a distinguished professional career, contributing his expertise to both academic institutions and research organizations. Over the years, he has taken on key roles that allowed him to bridge the gap between theoretical knowledge and practical applications. His leadership in various projects has been instrumental in shaping advancements within his domain, and his contributions continue to impact the scientific community.

Contributions and Research Focus 🔬

Dr. Vishal Srivastava has dedicated his research efforts to groundbreaking studies that have significantly advanced knowledge in his field. His work spans multiple innovative areas, focusing on addressing real-world challenges through scientific inquiry and technological solutions. With a keen interest in emerging trends, he has contributed to numerous publications and research collaborations, further solidifying his reputation as a thought leader. His research findings have not only added to academic literature but have also been applied in practical scenarios, demonstrating the real-world relevance of his work.

Accolades and Recognition 🏆

Dr. Vishal Srivastava’s contributions have been widely acknowledged, earning him prestigious accolades and recognitions from academic and professional organizations. His work has been featured in esteemed journals, and he has received awards for his pioneering research. These honors reflect his dedication, perseverance, and commitment to advancing knowledge in his field. His reputation as a scholar and innovator continues to grow as he receives invitations to share his insights at conferences, workshops, and industry events.

Impact and Influence 🌍

Beyond his research and professional achievements, Dr. Vishal Srivastava has played a crucial role in mentoring young researchers and students. His guidance has inspired many to explore new ideas and push the boundaries of conventional knowledge. His contributions extend beyond academia, as he actively collaborates with industry partners to bring research-driven innovations into real-world applications. Through his work, he has influenced policies, technological developments, and scientific progress, leaving a lasting impact on the field.

Legacy and Future Contributions 🚀

Dr. Vishal Srivastava’s legacy is one of innovation, excellence, and dedication to the pursuit of knowledge. As he continues his journey, he remains committed to pioneering research that addresses pressing global challenges. His future endeavors promise to bring further advancements, making significant contributions to science and technology. Through his ongoing work, he will continue to inspire future generations, shaping the future of research and innovation.

Publications

📄Cell-Based Small-Molecule Screening Identifying Proteostasis Regulators Enhancing Factor VIII Missense Mutant Secretion
Journal: Biomolecules
Year: 2025
Authors: Vishal Srivastava, Zhigang Liu, Wei Wei, Yuan Zhang, James C. Paton, Adrienne W. Paton, Tingwei Mu, Bin Zhang

📄 Mammalian Cargo Receptors for Endoplasmic Reticulum-to-Golgi Transport: Mechanisms and Interactions
Journal: Biochemical Society Transactions
Year: 2023
Authors: Zhang Y, Srivastava V, Zhang B

📄 The Combined Escherichia coli Nissle 1917 and Tryptophan Treatment Modulates Immune and Metabolome Responses to Human Rotavirus Infection in a Human Infant Fecal Microbiota Transplanted Malnourished Gnotobiotic Pig Model
Journal: mSphere
Year: 2022
Authors: Michael H, Srivastava V, Deblais L, Amimo JO, Chepngeno J, Saif LJ, Rajashekara G, Vlasova AN

📄 Obese Children Gut Microbiota Influences Inflammatory Mucosal Immune Pathways in the Respiratory Tract to Influenza Virus Infection: Optimization of an Ideal Duration of Microbial Colonization in a Gnotobiotic Pig Model
Journal: Microbiology Spectrum
Year: 2022
Authors: Renu S, Deblais L, Patil V, Schrock J, Kathayat D, Srivastava V, Feliciano-Ruiz N, Han Y, Ramesh A, Lakshmanappa Y S, Ghimire S, Dhakal S, Rajashekara G, Renukaradhya G J

📄 Evaluation of Novel Quorum Sensing Inhibitors Targeting Autoinducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens
Journal: Microbiology Spectrum
Year: 2022
Authors: Helmy Y A, Kathayat D, Deblais L, Srivastava V, Closs G, Tokarski IIR J, Ayinde O, Fuchs J R, Rajashekara G

Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Posted on 11/12/202411/12/2024 by Book of Award

Prof. Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Duke Kunshan University | China

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🎓 Early Academic Pursuits

Prof. Hyun Min Kim's journey in the scientific realm began with a Bachelor of Science in Life Science from Hanyang University, Seoul, South Korea, in 1997. This foundational phase nurtured his interest in microbiology, leading to a Master of Science in Life Science (Microbiology) from the same institution in 1999. His academic ascent culminated in a Ph.D. in Applied Biology (Genetics and Molecular Cell Biology) at Georgia Institute of Technology, USA, in 2009, where he explored genome instability, tri-nucleotide repeats, and their genetic implications. This solid academic grounding propelled him toward groundbreaking discoveries.

👨‍🔬 Professional Endeavors

Prof. Kim’s illustrious career spans continents and decades, beginning as a Chief Research Scientist at Hanyang University Medical School, focusing on cytokine profiling and toll-like receptor proteins. His time as a Research Assistant and later a Post-doctoral Fellow at Harvard Medical School cemented his expertise in genome editing and DNA damage repair mechanisms.
His roles as Associate Professor at Tianjin University and Duke Kunshan University underscore his contributions to epigenetics and the development of CRISPR-Cas9 systems. Currently, he serves as an Associate Professor of the Practice at Duke University, advancing molecular biology through cutting-edge research on histone demethylases and DNA damage repair.

🔬 Contributions and Research Focus

Prof. Kim's research revolves around epigenetic regulation and genome editing. He has made pivotal contributions to understanding histone demethylases' roles in DNA damage repair and cancer pathways. His work on CRISPR-Cas9 has refined genome editing techniques, particularly in C. elegans, enabling advances in genetic and therapeutic research. His publications, spanning high-impact journals like Biomolecules, Frontiers in Genetics, and Nature Communications, highlight his dedication to elucidating molecular mechanisms influencing genetic stability and cancer development.

🏆 Accolades and Recognition

Prof. Kim's academic excellence has been consistently recognized. From early scholarships at Hanyang University to the prestigious Sarstedt® Graduate Student Award for his Ph.D. accomplishments, his journey is marked by accolades. He received the Faculty Teaching Award at Tianjin University and multiple travel and mentorship awards, showcasing his dual strengths as a researcher and educator. His innovative work has also attracted significant funding, including grants from the National Natural Science Foundation of China and the Kunshan Shuangchuang Grant, totaling millions in support for his transformative projects.

🌟 Impact and Influence

Prof. Kim's efforts have shaped the scientific and academic communities. His leadership roles, such as organizing journal clubs at Harvard Medical School and contributing to editorial boards like Life Journal and Jove Journal, underscore his influence. As a mentor, he has guided budding researchers and students, exemplified by his award for mentoring undergraduates at Georgia Tech. His findings in genome stability, CRISPR-Cas9, and epigenetics continue to inspire advancements in genetic engineering and cancer therapy.

✨ Legacy and Future Contributions

With an eye on the future, Prof. Kim remains committed to unraveling the mysteries of molecular genetics and epigenetics. His work lays a foundation for next-generation cancer therapeutics and genome editing platforms. As a leader in both teaching and research, his legacy will undoubtedly endure, fostering innovation and collaboration in life sciences globally.

Publications

📄 Torenia sp. Extracts Contain Multiple Potent Antitumor Compounds with Nematocidal Activity, Triggering an Activated DNA Damage Checkpoint and Defective Meiotic Progression

Author: Meng, Q., Borris, R.P., Kim, H.-M.
Journal: Pharmaceuticals
Year: 2024

📄 Exploring the Impact of Onobrychis cornuta and Veratrum lobelianum Extracts on C. elegans: Implications for MAPK Modulation, Germline Development, and Antitumor Properties

Author: Meng, Q., Pathak, N., Ren, X., Borris, R.P., Kim, H.-M.
Journal: Nutrients
Year: 2024

📖 LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond

Author: Kim, H.-M., Liu, Z.
Journal: Biomolecules
Year: 2024

📖 Experimental Insights into the Interplay between Histone Modifiers and p53 in Regulating Gene Expression

Author: Kim, H.-M., Zheng, X., Lee, E.
Journal: International Journal of Molecular Sciences,
Year: 2023

📖 A Decade of CRISPR-Cas Genome Editing in C. elegans

Author: Kim, H.-M., Hong, Y., Chen, J.
Journal: International Journal of Molecular Sciences
Year: 2022

Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Posted on 03/08/202403/08/2024 by Book of Award

Dr. Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Pusan national university | South Korea

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🎓 Early Academic Pursuits

Dr. Dong Hee Kim began his academic journey with a Bachelor of Science in Biology from the University of Ulsan, Korea, in 2004. He continued at the same institution for his M.S.-Ph.D. in Biological Sciences under the mentorship of Professor Byung Ju Lee, completing his doctorate in 2012. His thesis, "Studies on the role of NELL2 in neuroprotection and neural differentiation," laid the foundation for his future research endeavors.

💼 Professional Endeavors

Dr. Kim has held various prestigious positions throughout his career. He is currently a Research Fellow at Pusan National University Hospital since November 2022. Previously, he served as a Research Professor at the University of Ulsan from January 2019 to May 2022, and as a Research Fellow at the same university from January 2015 to October 2016. His early postdoctoral work was conducted at UNIST from March 2013 to December 2014.

🧪 Contributions and Research Focus

Dr. Kim's research primarily revolves around neuroprotection, neural differentiation, and the molecular mechanisms underlying neurodegenerative diseases. His notable grants include funding from WISET for studying the function of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the brain, and multiple grants from the NRF of Korea, including studies on TonEBP function in hypothalamic leptin resistance and its role in degenerative brain disorders.

🏅 Accolades and Recognition

Throughout his career, Dr. Kim has received significant recognition for his contributions to biomedical research. His projects have been supported by prestigious grants, highlighting the impact and importance of his work in understanding brain functions and disorders. His research has also resulted in numerous publications in high-impact journals, further establishing his reputation in the field.

🌟 Impact and Influence

Dr. Kim's research has significantly advanced the understanding of neural mechanisms and their implications in neurodegenerative diseases. His work on the transcription regulation of key genes involved in brain function and inflammation has provided new insights into potential therapeutic targets. His publications have been widely cited, indicating the influence of his research on the scientific community.

📚 Legacy and Future Contributions

Dr. Kim's ongoing research continues to push the boundaries of our understanding of the brain. His current projects, funded by substantial grants, promise to uncover new mechanisms of brain function and disease. As he progresses in his career, Dr. Kim is poised to make further groundbreaking discoveries that will contribute to the field of biomedical science and technology.

Publications 📘

📄 Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Transcription Regulation of AgRP and POMC Genes

👩‍🔬 Authors: Kim DH*, Lee MJ, Kang D, Khang AR, Bae JH, Kim JY, Kim SH, Kang YH, Yi D.

📕 Journal: Curr Issues Mol Biol.

📅 Year: 2024

📄 Bridging Energy Need and Feeding Behavior: The Impact of eIF2α Phosphorylation in AgRP Neurons

👩‍🔬 Authors: Kim KK, Lee TH, Park BS, Kang D, Kim DH, Jeong B, Kim JW, Yang HR, Kim HR, Jin S, Back SH, Park JW, Kim JG, Lee BJ.

📕 Journal: Diabetes

📅 Year: 2023

📄 Sirtuin 1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to Energy Deficiency Response

👩‍🔬 Authors: Kang D, Yang HR, Kim DH, Kim KK, Jeong B, Park BS, Park JW, Kim JG, Lee BJ.

📕 Journal: Int J Mol Sci.

📅 Year: 2023

📄 Inhibition of LPAR1 Signaling in PDLSCs Reduces the Inflammatory Paracrine Effect on Primary Astrocyte Cells

👩‍🔬 Authors: Kim DH*, Seo EJ*, Kim YH, Jang IH.

📕 Journal: Int J Oral Biol.

📅 Year: 2022

📄 Transcriptional Regulatory Role of NELL2 in Preproenkphalin Gene Expression

👩‍🔬 Authors: Ha CM*, Kim DH*, Lee TH, Kim HR, Choi JI, Kim Y, Kang DS, Park JW, Oieda S, Jeong JK, Lee BJ.

📕 Journal: Mol Cells

📅 Year: 2022

Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Posted on 20/04/202420/04/2024 by Book of Award

Mr. Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Hebrew University of Jerusalem | Israel

Author Profile

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Early Academic Pursuits

Mr. Jairus Nandwa embarked on his academic journey with a Bachelor of Technology in Industrial Microbiology and Biotechnology from The Technical University of Mombasa, Kenya. He further pursued a Master of Science in Biosciences at COMSATS University Islamabad, Pakistan, and is currently pursuing a PhD in Genetics at The Hebrew University of Jerusalem, focusing on circular RNAs, SNORDS, and miRNAs in cancer under the guidance of Professor Ruth Sperling.

Professional Endeavors

With a robust academic background, Mr. Nandwa engaged in various research experiences, including his role as a Graduate Student/Research Student at the Cancer Genetics and Epigenetics Lab, COMSATS University, Pakistan. He also served as a Laboratory Analyst during his BTech internship at the Regional Veterinary Investigation Laboratory, Kenya.

Contributions and Research Focus

Mr. Nandwa's research interests span non-coding RNAs in gene expression regulation, tumor microenvironment, biomarker/therapeutic discovery, DNA repair mechanisms, and biological data analysis. He has authored several publications and presented his research at esteemed conferences globally.

Accolades and Recognition

His notable publications include research on miRNA-4716–3p and its association with blood cancer pathogenesis, earning recognition in Non-Coding RNA Research. He has also received awards such as the Queen Elizabeth Commonwealth Scholarship and First Class Honors in BTech Industrial Microbiology and Biotechnology.

Impact and Influence

Mr. Nandwa's contributions extend beyond academia, with leadership roles in cancer education initiatives and community service engagements. His research and volunteer efforts demonstrate a commitment to advancing scientific knowledge and addressing societal challenges.

Legacy and Future Contributions

As Mr. Nandwa continues his doctoral studies and research pursuits, his dedication to understanding the intricacies of cancer biology and contributing to innovative solutions positions him as a promising researcher in the field of genetics. His leadership, academic achievements, and community impact foreshadow a legacy of scientific excellence and social responsibility.

Notable Publications

In silico analysis of RPS4X (X-linked ribosomal protein) with active components from black seed (Nigella sativa) for potential treatment of multiple sclerosis 2024

Targeting allosteric sites on PDK-1 and PLK-1 with bioactive compounds from Daucus carota as a potential therapy for triple-negative breast cancer 2023

Assist Prof Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Posted on 05/01/202405/01/2024 by Book of Award

Assist Prof Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

National and Kapodistrian University of Athens | Greece

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Early Academic Pursuits

Andreas Agathangelidis initiated his scientific journey at Thessaloniki's "G. Papanikolaou" hospital, delving into Chronic Lymphocytic Leukemia (CLL) and antigens for his diploma thesis. Subsequently, his Ph.D. at Aristotle University focused on immunogenetics in B-cell malignancies.

Professional Endeavors

Agathangelidis conducted groundbreaking studies during his Ph.D., notably refining CLL molecular classification using a sizable patient cohort. His postdoctoral research at San Raffaele Scientific Institute, Milan, explored CLL and Monoclonal B lymphocytosis (MBL) under Professor Paolo Ghia, broadening his expertise in advanced genetic methodologies.

Contributions and Research Focus

Significant contributions include expansive studies on CLL patients and the largest worldwide series on Mantle Lymphoma (MCL), emphasizing the role of antigens in disease progression. He conducted diverse immunoprofiling studies, exploring gene rearrangements and subtyping based on immunogenetics, oncogenetics, and immunophenotype integration.

Accolades and Recognition

Agathangelidis' pioneering research secured recognition, including fellowships from the HFRI Foundation and industry funding from Gilead Sciences. His leadership in the "CLLon" project, studying the B cell receptor's role in CLL and MBL development, represents a significant achievement in cancer genetics.

Impact and Influence

His work has significantly challenged prevailing views in disease mechanisms, refining classifications, and paving the way for targeted therapies for B-cell malignancies. The extensive studies he led have had a substantial impact on understanding disease ontogeny and the development of potential treatments.

Legacy and Future Contributions

Currently an Assistant Professor at the National and Kapodistrian University of Athens, Agathangelidis continues his research using advanced NGS technologies. His focus on elucidating the B cell receptor's role in CLL and MBL development through deep sequencing and bioinformatics is poised to bring forth notable advancements in cancer genetics and potential therapeutic avenues.

Notable Publications

Recurrent mutations refine prognosis in chronic lymphocytic leukemia 2014 (219)

A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study 2015 (179)

Antigen receptor stereotypy in chronic lymphocytic leukemia 2016 (99)