Yuanyuan Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Dr. Yuanyuan Li | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Guangdong Provincial Laboratory of Traditional Chinese Medicine | China

Author Profile

Scopus

🎓 Early Academic Pursuits

Dr. Li’s academic path began with an exceptional undergraduate performance in Chemistry at Jilin University. Her passion for science led her to pursue a Master’s degree in Analytical Chemistry and subsequently a Ph.D. in the same field, which she completed in July 2014 under the guidance of esteemed professor Zhang Shusheng. During her doctoral studies, she received comprehensive training in analytical techniques and developed a strong interest in practical applications related to food and environmental safety.

🏢 Professional Endeavors

In 2014, Dr. Li joined the School of Public Health at Jilin University as a faculty member. She steadily rose through the ranks to become a full professor and doctoral supervisor. Her responsibilities have included leading multiple high-level national projects, mentoring graduate students, and engaging in collaborative research across disciplines. She has become a pivotal figure in shaping the academic direction of the university’s public health research programs.

🔬 Contributions and Research Focus

Dr. Li’s research primarily focuses on food safety risk assessment, monitoring of toxic and hazardous substances in the food chain, and the development of advanced analytical methods. She has published over 80 high-impact academic papers, including articles in Analytical ChemistryBiosensors and BioelectronicsACS Sensors, and TrAC Trends in Analytical Chemistry. Her work integrates innovative electrochemical and optical biosensing techniques, making significant advancements in the detection of pesticide residues, foodborne pathogens, and environmental pollutants.

🏆 Accolades and Recognition

Her excellence has not gone unnoticed. Dr. Li has received several prestigious honors, including the “Young Elite Scientists Sponsorship Program” by the China Association for Science and Technology and the First Prize for Scientific and Technological Progress by the Jilin Provincial Government. She has also served as a visiting scholar at the University of Michigan, where she broadened her international research collaboration network.

🌍 Impact and Influence

Dr. Li's research has had a profound impact on public health, food regulation, and environmental policy. Her cutting-edge methodologies contribute directly to national standards and have been implemented in real-world food safety monitoring. She is also an active member of professional organizations and frequently serves as a reviewer for top-tier scientific journals, thereby shaping the future of analytical science and public health on both national and global scales.

🔮 Legacy and Future Contributions

Looking forward, Dr. Yuanyuan Li is poised to continue her groundbreaking work in biosensor development and integrated health risk assessment. Her vision is to establish more comprehensive detection platforms that can safeguard food and environmental quality, ultimately enhancing public health resilience. As a mentor, researcher, and innovator, her legacy is one of rigorous science combined with a deep commitment to societal well-being.

 

Publications


📄 Shenxiong Yixin Decoction polysaccharides exert therapeutic effects against myocardial ischemia-reperfusion injury via intestinal exosomal microRNA-21 regulation

Authors:
De-Sheng Xu, Yan Wang, Zi-Rui Li, Ping-Li Mo, Ming-Tai Chen, Rui-Zhi Zhao, Zheng Fan, Wen-Jie Mo, Qi-Lu Li, Fang-Cao Pi, Qi-Di Sun, Juan-Min Li, Yun-Da Yao, Jian-Ping Chen, Yuan-Yuan Li, Jie-Nan Luan, Shang-Bin Zhang, Ying Xie, Hua Zhou

Journal: Pharmacological Research   Year: 2025


📄 Syringic acid attenuates acute lung injury by modulating macrophage polarization in LPS-induced mice

Authors:
W.-T. Wang, Y.-Y. Zhang, Z.-R. Li, J.-M. Li, H.-S. Deng, Y.-Y. Li, H.-Y. Yang, C.-C. Lau, Y.-J. Yao, H.-D. Pan, L. Liu, Y. Xie, H. Zhou et al.

Journal: Phytomedicine   Year: 2024


📄 A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment

Authors:
M.-T. Chen, F.R. Huang, B.-H. Chen, J.-L. Kang, Y.-J. Yao, M.-N. Liu, Y.-Y. Li, Y.-Q. Li, T.-R. Zhou, D.-T. Peng, L.-D. Luo, C.-S. Wei, Y.-F. Xing, Q.-B. Wu, H. Zhou, G.-D. Tong

Journal: Biomedicine & Pharmacotherapy   Year: 2023

Peng Chen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof. Peng Chen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Qingdao University | China

Author Profile

Scopus

Orcid

Early Academic Pursuits 🎓

Prof. Peng Chen's journey in medical research began with a strong foundation in clinical medicine and biomedical sciences. She earned her Bachelor of Medicine degree from Taishan Medical College (1999-2004), where she gained essential medical knowledge and clinical training. Her pursuit of advanced expertise led her to Capital University of Medical Sciences (2004-2007), where she obtained a Master of Science degree, focusing on medical research methodologies and specialized clinical studies. To further deepen her understanding and expertise, she pursued a Doctor of Medicine (2009-2012) at Qingdao University, refining her specialization in ophthalmology and regenerative medicine.

Professional Endeavors 🔬

After completing her master's degree, Prof. Chen embarked on her professional career at the Shandong Eye Institute (2007-2016), a renowned institution dedicated to ophthalmology research. During her tenure, she made significant contributions to vision sciences and ocular disease research, strengthening her expertise in eye-related disorders. In 2016, she transitioned to Qingdao University, where she currently serves as a leading researcher and faculty member. Her role at the university allows her to conduct cutting-edge research on ophthalmology and liver regeneration, mentor young medical scientists, and contribute to the advancement of medical science.

Contributions and Research Focus 🔍

Prof. Chen's research has significantly impacted liver regeneration, macrophage efferocytosis, and ophthalmology, particularly in understanding cellular mechanisms and disease pathophysiology. Some of her key contributions include:

  • Liver Regeneration and Macrophage Efferocytosis: Her recent studies have explored the NLRP3 inflammasome's role in constraining liver regeneration by impairing macrophage efferocytosis (Sci Adv., 2025). Additionally, she has investigated the role of Aquaporin-5 in facilitating liver regeneration via the ROS/GSDMD pathway (Cell Signal., 2025) and how extracellular vesicles containing GAS6 protect the liver from ischemia-reperfusion injury (Cell Death Discov., 2024).
  • Ophthalmology and Ocular Disease Research: She has studied the retinoic acid synthesis pathway in AQP5-deficient mice and its implications for dry eye disease (Invest Ophthalmol Vis Sci., 2024). Her research has also examined the regulation of axon guidance by Slit2 and Netrin-1 signaling in lacrimal gland development (Invest Ophthalmol Vis Sci., 2023).

Prof. Chen’s research not only deepens scientific knowledge in these areas but also paves the way for novel therapeutic strategies for liver and eye diseases.

Accolades and Recognition 🏆

Prof. Chen’s contributions to medical science have been widely recognized through prestigious research grants and peer-reviewed publications. She has received:

  • National Natural Science Foundation of China (2020-2023): RMB 550,000 for research on AQP5’s protective role in lens transparency through miRNA-mediated autophagy.
  • Shandong Provincial Natural Science Foundation (2018-2021): RMB 150,000 for the identification and functional study of Fuchs corneal endothelial dystrophy gene.

Her research has been featured in top-tier scientific journals, including Science Advances, Cell Signal, Cell Death Discovery, and Investigative Ophthalmology & Visual Science, reinforcing her status as a leading expert in regenerative medicine and ophthalmology.

Impact and Influence 🌍

Prof. Chen’s work bridges fundamental research and clinical applications, making a profound impact in both ophthalmology and liver disease treatment. Her findings on macrophage efferocytosis and aquaporins have opened new avenues for therapeutic interventions in liver regeneration, while her contributions to ocular disease mechanisms have enhanced the understanding of corneal and lacrimal gland pathophysiology.

Through her mentorship, collaborations, and academic contributions, she continues to shape the next generation of medical researchers and clinicians, strengthening Qingdao University’s reputation as a hub for medical research excellence.

Legacy and Future Contributions 🚀

With an established track record in liver regeneration and ophthalmic research, Prof. Peng Chen’s future contributions are expected to drive medical innovations in regenerative medicine and precision healthcare. Her work on cellular signaling pathways, extracellular vesicles, and aquaporins will likely inspire new therapeutic breakthroughs in both systemic and ocular diseases. As she continues to lead cutting-edge research, mentor young scientists, and contribute to transformative discoveries, Prof. Chen’s legacy will be one of scientific excellence, innovation, and meaningful impact on global healthcare.

Publications


  • 📄NLRP3 inflammasome constrains liver regeneration through impairing MerTK-mediated macrophage efferocytosis

    • Journal: Science Advances
    • Year: 2025
    • Authors: Wei S, Guan G, Luan X, Yu C, Miao L, Yuan X, Chen P*, Di G*

  • 📄Aquaporin-5 facilitates liver regeneration following hepatectomy via ROS/GSDMD pathway

    • Journal: Cell Signaling
    • Year: 2025
    • Authors: Li B, Di G, Ge H, Song P, Han W, Sun H, Wang D, Chen P*, Wang Y*

  • 📄Extracellular vesicles containing GAS6 protect the liver from ischemia-reperfusion injury by enhancing macrophage efferocytosis via MerTK-ERK-COX2 signaling

    • Journal: Cell Death Discovery
    • Year: 2024
    • Authors: Miao L, Yu C, Guan G, Luan X, Jin X, Pan M, Yang Y, Yan J, Chen P*, Di G*

  • 📄Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice

    • Journal: Investigative Ophthalmology & Visual Science
    • Year: 2024
    • Authors: Ge H, Di G, Li B, Han W, Song P, Han S, Wang D*, Chen P*

  • 📄Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice

    • Journal: Investigative Ophthalmology & Visual Science
    • Year: 2023
    • Authors: Bai Y, Di G, Ge H, Li B, Zhang K, Zhang D, Wang D*, Chen P*