Anna Santoro | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

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Dr. Anna Santoro | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

Beth Israel Deaconess Medical Center | United States

Dr. Anna Santoro’s research profile reflects a strong and sustained contribution to biomedical and toxicological sciences, with a particular focus on inflammatory pathways, metabolic regulation, environmental toxicants, and neuroendocrine mechanisms. Her scholarly output comprises 28 peer-reviewed documents, which together have received 1,584 citations across 1,472 citing documents, demonstrating broad international impact and cross-disciplinary relevance. With an h-index of 22, her work shows both productivity and consistent citation performance. Key investigations explore the biological effects of non-dioxin-like polychlorinated biphenyls on cellular apoptosis, lipid metabolism, and endocrine signaling, alongside influential studies on palmitoylethanolamide and its protective roles in metabolic disorders, hypertension, renal injury, and neuroinflammation. Her publications in high-impact journals such as Toxicology Letters, Endocrinology, PLoS One, and Journal of Nutritional Biochemistry highlight rigorous experimental approaches and translational relevance, positioning her research as a significant reference point in toxicology, pharmacology, and metabolic disease research.

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Featured Publications

Judith Röske | Biochemistry, Genetics and Molecular Biology | Women Research Award

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Mrs. Judith Röske | Biochemistry, Genetics and Molecular Biology | Women Research Award

University of Luebeck | Germany

Mrs. Judith Röske is a dedicated researcher with a strong focus on molecular virology, antiviral drug discovery, and protease-targeted therapeutic development, contributing to 13 scientific publications across high-impact journals. Her work explores the binding behavior of small-molecule inhibitors to viral 3C proteases, including SARS-CoV-2, EV-D68, EV-A71, and HAV, as well as host proteases such as cathepsins and calpain-1. With expertise in photometry, nanoDSF, MST, and SPR, she has optimized methods for determining key biochemical parameters such as IC₅₀, Tm, and Kᴅ, enabling the effective screening of lead compounds for broad-spectrum antivirals. Her research further investigates RNA-binding mechanisms in HAV 3C protease, shedding light on dual-targeting strategies that may advance anti-picornaviral drug development. She has contributed to influential studies on SARS-CoV-2 main protease inhibitors, including work on novel warhead chemistries, α-ketoamide derivatives, and diastereomeric optimization, reinforcing her impact in antiviral medicinal chemistry. Additionally, earlier contributions in transplant biology and liver preservation highlight her versatility in biochemical and molecular research. Through rigorous structural, kinetic, and biophysical analyses, her body of work adds valuable insight into protease inhibition and therapeutic innovation, supported by a growing citation record within the scientific community.

Profiles : Scopus | Orcid

Featured Publications

Theodoropoulou, M. A., El Kilani, H., Mantzourani, C., Jochmans, D., Neyts, J., Zhang, K., Röske, J., Kokotou, M. G., Hilgenfeld, R., & Kokotos, G. (2025). Thiazolyl 4-carboxylate ketone as a new warhead for a highly potent SARS-CoV-2 main protease inhibitor. European Journal of Medicinal Chemistry, 25(11), 118436.

Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., et al. (2025). Structure-based optimization of pyridone α-ketoamides as inhibitors of the SARS-CoV-2 main protease. Journal of Medicinal Chemistry, 68(1).

Cooper, M. S., Zhang, L., Ibrahim, M., Zhang, K., Sun, X., Röske, J., Göhl, M., Brönstrup, M., Cowell, J. K., Sauerhering, L., et al. (2022). Diastereomeric resolution yields highly potent inhibitor of SARS-CoV-2 main protease. Journal of Medicinal Chemistry.

Bernard, V., Gebauer, N., Dinh, T., Stegemann, J., Feller, A. C., & Merz, H. (2014). Applicability of next-generation sequencing to decalcified formalin-fixed and paraffin-embedded chronic myelomonocytic leukaemia samples. International Journal of Clinical and Experimental Pathology.

Le Minh, K., Berger, A., Eipel, C., Kuhla, A., Minor, T., Stegemann, J., & Vollmar, B. (2011). Uncoupling protein-2 deficient mice are not protected against warm ischemia/reperfusion injury of the liver. Journal of Surgical Research, 167.

Stegemann, J., Hirner, A., Rauen, U., & Minor, T. (2010). Use of a new modified HTK solution for machine preservation of marginal liver grafts. Journal of Surgical Research.

Koetting, M., Stegemann, J., & Minor, T. (2010). Dopamine as additive to cold preservation solution improves postischemic integrity of the liver. Transplant International, 23.

Minor, T., Stegemann, J., Hirner, A., & Koetting, M. (2009). Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning. Liver Transplantation.

Stegemann, J., & Minor, T. (2009). Energy charge restoration, mitochondrial protection and reversal of preservation-induced liver injury by hypothermic oxygenation prior to reperfusion. Cryobiology.

Stegemann, J., Hirner, A., Rauen, U., & Minor, T. (2009). Gaseous oxygen persufflation or oxygenated machine perfusion with Custodiol-N for long-term preservation of ischemic rat livers? Cryobiology.

Le Minh, K., Kuhla, A., Abshagen, K., Minor, T., Stegemann, J., Ibrahim, S., Eipel, C., & Vollmar, B. (2009). Uncoupling protein-2 deficiency provides protection in a murine model of endotoxemic acute liver failure. Critical Care Medicine.

Manekeller, S., Seinsche, A., Stegemann, J., & Hirner, A. (2008). Optimising post-conditioning time of marginal donor livers. Langenbeck's Archives of Surgery.

Manekeller, S., Schuppius, A., Stegemann, J., Hirner, A., & Minor, T. (2007). Role of perfusion medium, oxygen and rheology for endoplasmic reticulum stress-induced cell death after hypothermic machine preservation of the liver. Transplant International.

Giovanni Smaldone | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Dr. Giovanni Smaldone | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

IRCCS Synlab SDN | Italy

Dr. Giovanni Smaldone is a highly accomplished researcher whose work spans molecular biology, structural biochemistry, oncology, immunology, and advanced diagnostic technologies. With 1,037 citations, 83 published works, and an h-index of 18, his contributions reflect both productivity and strong scientific impact. His research integrates structural biology, NMR spectroscopy, molecular interactions, and translational oncology, with a particular emphasis on childhood acute lymphoblastic leukemia (ALL). He has led and contributed to numerous funded research projects, including competitive grants focused on long non-coding RNAs, epigenetic markers, and the KCTD protein family in pediatric leukemia. His studies also extend into protein delivery systems, nanogels, cellular imaging, and biobank development for rare pediatric disorders. Dr. Smaldone’s recent publications highlight advancements in 3D refractive index tomography for leukemia cell analysis, targeted drug-delivery platforms, diagnostic biomarkers such as circular RNAs and LINC00958, and the structural mechanisms underlying KCTD–Cullin 3 interactions. His work frequently appears in high-impact journals across molecular sciences, biomedical engineering, nanotechnology, and clinical research. Additionally, he has presented widely at national and international scientific conferences, contributing to knowledge dissemination in cellular biophysics, protein structure, pediatric oncology, and advanced molecular diagnostics.

Profiles : Scopus | Orcid

Featured Publications

Bianco, V., Pirone, D., Schiavo, M., Bianco, V., Miccio, L., Memmolo, P., Smaldone, G., Pecoraro, G., Altieri, F., Salvatore, M., et al. (2026). Quantitative mapping of leukemia cells and intracellular lipid droplets using 3D refractive index tomography in flow cytometry. IEEE Journal of Selected Topics in Quantum Electronics.

Pizzella, M., Accardo, A., Mercurio, F. A., Sibillano, T., Gallo, E., Morelli, G., Smaldone, G., Giannini, C., Leone, M., Balasco, N., et al. (2025). Structural and functional characterization of self-assembling fragments identified from the transthyretin amyloid-like structure. Nanoscale.

Leone, I., Costabile, V., Smaldone, G., Franzese, M., Soricelli, A., & D’Agostino, A. (2025). Arthrospira platensis attenuates endothelial inflammation and monocyte activation. International Journal of Molecular Sciences.

Gallo, E., Smaldone, G., Cimmino, L., Braile, M., Orlandella, F. M., Luciano, N., Accardo, A., & Salvatore, G. (2025). Fmoc-FF nanogel-mediated delivery of doxorubicin and curcumin in thyroid cancer cells. Pharmaceutics.

Balasco, N., Esposito, L., Smaldone, G., Salvatore, M., & Vitagliano, L. (2024). A comprehensive analysis of the structural recognition between KCTD proteins and Cullin 3. International Journal of Molecular Sciences.

Bianco, V., Wang, Z., Brancato, V., Coppola, L., Smaldone, G., D’Aiuto, M., Mossetti, G., Maffettone, P. L., Salvatore, M., & Ferraro, P. (2024). Adaptive space-time digital holography for imaging flow cytometry and tissue slide analysis. In Digital Holography and Three-Dimensional Imaging (DH 2024).

Coppola, L., Grimaldi, A. M., Sarnacchiaro, G., Di Fasano, M. S., Smaldone, G., & Salvatore, M. (2024). An overview of Synlab SDN Biobank’s quality control system. Scientific Reports.

De Martino, L., Mirabelli, P., Quaglietta, L., Ferrara, U. P., Picariello, S., De Gennaro, D. V., Aiello, M., Smaldone, G., Aliberti, F., Spennato, P., et al. (2024). Biobank for craniosynostosis and faciocraniosynostosis: A study protocol. Child’s Nervous System.

Bianco, V., Valentino, M., Pirone, D., Miccio, L., Memmolo, P., Brancato, V., Coppola, L., Smaldone, G., D’Aiuto, M., & Mossetti, G. (2024). Classifying breast cancer and fibroadenoma tissue biopsies using fractal biomarkers in Fourier ptychographic microscopy. Computational and Structural Biotechnology Journal.

De Martino, L., Mirabelli, P., Quaglietta, L., Ferrara, U. P., Picariello, S., De Gennaro, D. V., Aiello, M., Smaldone, G., Aliberti, F., Spennato, P., et al. (2024). Correction: Biobank for craniosynostosis and faciocraniosynostosis. Child’s Nervous System.

Gallo, E., Diaferia, C., Smaldone, G., Rosa, E., Pecoraro, G., Morelli, G., & Accardo, A. (2024). Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells. Scientific Reports.

Gallo, E., Diaferia, C., Smaldone, G., Rosa, E., Pecoraro, G., Morelli, G., & Accardo, A. (2024). Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells. Research Square.

Filomena, A., Smaldone, G., Ginevra, S., Santiago, N., Di Fasano, M. S., Peppino, M., Alessandra, C., Antonia, D. M., Giuliana, B., Rosanna, P., et al. (2024). Identification of a circular RNA isoform of WASHC2A as a prognostic factor for high-risk pediatric B-ALL. Biomedicine & Pharmacotherapy.

Raymundo, J. R., Zhang, H., Smaldone, G., Zhu, W., Daly, K. E., Glennon, B. J., Pecoraro, G., Salvatore, M., Devine, W. A., Lo, C. W., et al. (2024). KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions. Journal of Clinical Investigation.

Altieri, F., Buono, L., Lanzilli, M., Mirabelli, P., Cianflone, A., Beneduce, G., De Matteo, A., Parasole, R., Salvatore, M., & Smaldone, G. (2024). LINC00958 as a diagnostic and prognostic biomarker of childhood B-cell acute lymphoblastic leukemia. Frontiers in Oncology.

Anita Kavrakova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Mrs. Anita Kavrakova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Genetic Medico-Diagnostic Laboratory “Genica” | Bulgaria

Mrs. Anita Kavrakova is a distinguished molecular biologist and project manager with extensive experience in medical genetics and diagnostic research. Since 2019, she has been serving as Project Manager at Genetic Medico-Diagnostic Laboratory “Genica” and Genome Center Bulgaria AD in Sofia, where she oversees laboratory projects, implements innovative diagnostic techniques, ensures compliance with national and international standards, and actively contributes to scientific research through conferences, publications, and collaborative studies. Prior to this role, she worked as a Molecular Biologist at Genica (2008–2018), conducting advanced molecular analyses including PCR, qPCR, gene sequencing, and immunohistochemistry, with a focus on cancer genetics, particularly prostate and cervical cancers. She has also been a part-time assistant at the Department of Medical Chemistry and Biochemistry, Medical University Sofia, since 2012, training students in theoretical and practical biochemistry. Dr. Kavrakova earned her PhD in Genetics from Medical University Sofia in 2015, investigating molecular markers in prostate cancer for improved diagnostics and patient management, following an MS in Genetics and a Bachelor in Biology from Sofia University “St Kliment Ohridski.” She has contributed to numerous national and international research projects on infectious agents, reproductive failure, and cancer etiology, authored multiple publications, and actively participates in innovation evaluation and scientific advisory roles, demonstrating leadership, analytical skills, and a commitment to advancing molecular diagnostics and biomedical research.

Profiles : Scopus | Orcid

Featured Publications

Todorova, E., Kavrakova, A., Derimachkovski, G., Georgieva, B., Odzhakov, F., Bachurska, S., Terziev, I., Boyadzhieva, M. E., Valkov, T., Popov, E., Slavov, C., Tourtourikov, I., Mitev, V., & Todorova, A. (2025). Human Herpes Virus genotype and immunological gene expression profile in prostate cancer with prominent inflammation. International Journal of Molecular Sciences, 26(10), 4945.

Todorova, E., & Kavrakova, A., Derimachkovski, G., Georgieva, B., Kalenderova, S., Odzhakov, F., Bachurska, S., Boyadzhieva, M. E., Terziev, I., Genova, M., Mitev, V., & Todorova, A. (2025). Pathogenic contribution of human papillomaviruses and Epstein-Barr virus to prostate cancer in Bulgarian patients. C. R. Acad. Bulg. Sci. (submitted).

Mesechkova, K., Kavrakova, A., Georgieva, B., Sigridov, I., Miteva, A., Mitev, V., & Todorova, A. (2023). Bacterial and viral pathogens implicated in female reproductive failure investigated on menstrual blood. C. R. Acad. Bulg. Sci., 76(3), 394–406.

Mesechkova, K., Kavrakova, A., Georgieva, B., Sigridov, I., Mitev, V., & Todorova, A. (2023). Non-invasive diagnostics of reproductive failure with infectious etiology on menstrual tissue. Acta Medica Bulgarica, 50(3).

Mesechkova, K., Kavrakova, A., Todorova, E., Georgieva, B., Sigridov, I., Mitev, V., & Todorova, A. (2023). Role of bacterial and viral infections and co-infections in miscarriages. Acta Medica Bulgarica, 50(4).

Kavrakova, A., Todorova, A., Georgieva, B., Anachkov, K., Yanev, K., Ivanov, G., & Mitev, V. (2018). Investigation of noninvasive urine specimens with molecular fluctuations for a presence of high-risk human papilloma viruses as an inflammatory cofactor in prostate cancer. Journal of Biology and Medicine.

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2015). Molecular and clinico-histological data in aggressive prostate cancer patients from Bulgaria. JBUON, 20(2).

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2015). Molecular and clinicopathological aspects of prostate cancer in Bulgarian probands. Journal of Pathology and Oncology Research.

Tsvetkova, A., Todorova, A., Todorov, T., Georgiev, G., Drandarska, I., & Mitev, V. (2014). Molecular profile and clinicopathological aspects of prostate cancer in Bulgarian patients. Journal of BOD, 4, 18–26.

Tsvetkova, A., Kadiyska, T., Georgiev, G., Drandarska, I., Todorova, A., & Mitev, V. (2013). Molecular-genetic approach in combination with clinical and histological data for diagnostics of prostate cancer. Journal of Oncology, 3, 50–55.

 

 

Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Mrs. Valentina Mihaylova | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Medical University-Plovdiv | Bulgaria

Mrs. Valentina Mihaylova is a dedicated researcher and specialist in medical chemistry with a strong focus on cellular metabolism, mitochondrial function, oxidative stress, and autoimmune diseases. With an h-index of 2, she has authored five scientific publications, which have collectively garnered 14 citations, reflecting her growing impact in medical biology and clinical research. Her work encompasses the study of markers of oxidative stress and insulin resistance in chronic autoimmune Hashimoto’s thyroiditis, cellular metabolic profiling in children with autism spectrum disorders, and the evaluation of therapeutic effects in rheumatoid arthritis through mitochondrial function and bioenergetic metabolism. Mrs. Mihaylova’s research also explores intestinal permeability, systemic inflammation, and the pharmacological effects of treatments such as methotrexate and JAK inhibitors on mitochondrial function and oxidative stress. She has actively contributed to numerous national and international conferences, presenting pioneering findings on the role of mitochondria, autophagy, and inflammation in autoimmune and rheumatologic conditions. Her academic and professional trajectory, spanning positions from clinical chemist to Master of Medical Chemistry at the Medical University of Plovdiv, is marked by a commitment to advancing knowledge in medical biology and translational research. Through her multidisciplinary approach, Mrs. Mihaylova continues to elucidate complex biochemical mechanisms underlying disease pathology and therapeutic responses, establishing herself as an emerging contributor to the field of medical and clinical biochemistry.

Profiles : Scopus | Orcid

Featured Publications

Mihaylova, V., Tomov, D., Karalilova, R., Batalov, Z., Batalov, A., Sarafian, V., & Kazakova, M. (2025). Effects of methotrexate and tofacitinib on mitochondrial function and oxidative stress in human synovial cells in vitro. International Journal of Molecular Sciences, 26(17), 8173.

Tomov, D. G., Levterova, B. A., Mihaylova, V. N., Troev, D. M., Miteva, M. Z., Uzunova, Y. I., & Orbetzova, M. M. (2024). Influence of the increase in intestinal permeability and microbiota change in the development of Hashimoto's thyroiditis: A systematic review. Endocrine and Metabolic Science, 100195.

Mihaylova, V., Kazakova, M., Batalov, Z., Karalilova, R., Batalov, A., & Sarafian, V. (2023). JAK inhibitors improve ATP production and mitochondrial function in rheumatoid arthritis: A pilot study. Rheumatology International.

Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Assist. Prof. Dr. Panpan Hou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Macau University Of Science And Technology | Macau

Assist. Prof. Dr. Panpan Hou is a distinguished researcher in the field of Biomedical Engineering and Biophysics, with a prolific record of 375 documents, 541 citations, and an h-index of 16. After obtaining a B.S. in Biomedical Engineering and a Ph.D. in Biophysics from Huazhong University of Science and Technology, Dr. Hou completed postdoctoral training at Washington University in St. Louis before joining Macau University of Science and Technology as an Assistant Professor in 2021. Dr. Hou’s research focuses on ion channel physiology, voltage-sensor domain (VSD) mechanisms, and electro-mechanical coupling, elucidating complex molecular processes such as the VSD-pore coupling in KCNQ1 channels and identifying novel modulators with therapeutic potential. He has made significant contributions to drug screening, cardiovascular disease modeling, and electrophysiology, publishing high-impact work in journals including Nature Communications, PNAS, eLife, Circulation Research, and Scientific Reports. Dr. Hou has received multiple awards including the AHA Postdoctoral Fellowship, Best Poster Awards at international symposia, and the 2025 Best Research Output Award from Macau University of Science and Technology. Beyond research, he actively mentors students, serves on editorial boards, and contributes to national and international scientific societies. With a strong track record of innovation, mentorship, and high-impact publications, Dr. Hou exemplifies excellence in biomedical research and is poised to advance the understanding of ion channel physiology and therapeutic interventions.

Profiles : Scopus | Orcid | Google Scholar

Featured Publications

Zhong, L., Lin, X., Cheng, X., Wan, S., Hua, Y., Nan, W., Hu, B., Peng, X., Zhou, Z., Zhang, Q., Yang, H., Noé, F., Yan, Z., Jiang, D., Zhang, H., Liu, F., Xiao, C., Zhou, Z., Mou, Y., Yu, H., Ma, L., Huang, C., Wong, V. K. W., Chung, S. K., Shen, B., Jiang, Z.-H., Neher, E., Zhu, W., Zhang, J., & Hou, P. (2025). Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating. Cell Research.

Hou, P., Zhao, L., Zhong, L., Shi, J., Wang, H. Z., Gao, J., Liu, H., Zuckerman, J., Cohen, I. S., & Cui, J. (2024). The fully activated open state of KCNQ1 controls the cardiac “fight-or-flight” response. PNAS Nexus.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2022). Author correction: A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Dou, A., Kang, P. W., Hou, P., Zaydman, M. A., Zheng, J., Jegla, T., & Cui, J. (2021). Principles of sensor-effector organization in six-transmembrane ion channels.

Lin, Y., Grinter, S. Z., Lu, Z., Xu, X., Wang, H. Z., Liang, H., Hou, P., Gao, J., Clausen, C., & Shi, J. (2021). Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. Proceedings of the National Academy of Sciences.

Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N.-D., Hou, P., & Zhao, W. (2020). A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation. Communications Biology.

Taylor, K. C., Kang, P. W., Hou, P., Yang, N.-D., Kuenze, G., Smith, J. A., Shi, J., Huang, H., McFarland White, K., & Peng, D. (2020). Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. eLife.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2020). Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation. Nature Communications.

Zhu, W., Mazzanti, A., Voelker, T. L., Hou, P., Moreno, J. D., Angsutararux, P., Naegle, K. M., Priori, S. G., & Silva, J. R. (2019). Predicting patient response to the antiarrhythmic mexiletine based on genetic variation: Personalized medicine for long QT syndrome. Circulation Research.

Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N.-D., Liu, Y., Shi, J., Xu, X., McFarland White, K., Zaydman, M. A., Kasimova, M. A., Seebohm, M., Zhong, L., Zou, X., Tarek, M., & Cui, J. (2019). Two-stage electro-mechanical coupling of a KV channel in voltage-dependent activation.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling. eLife.

Hou, P., Shi, J., McFarland White, K., Gao, Y., & Cui, J. (2019). ML277 specifically enhances pore opening of KCNQ1 with VSD at the activated state by modulating VSD-pore coupling.

Hou, P., Eldstrom, J., Shi, J., Zhong, L., McFarland, K., Gao, Y., Fedida, D., & Cui, J. (2017). Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening. Nature Communications.

Shadab Ahamad | Biochemistry, Genetics and Molecular Biology | Best Scholar Award

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Mr. Shadab Ahamad | Biochemistry, Genetics and Molecular Biology | Best Scholar Award

Sri Sathya Sai University for Human Excellence | India

Mr. Shadab Ahamad is a dedicated life sciences researcher specializing in biotechnology, genomics, and congenital heart disease (CHD) studies. He is currently pursuing a Ph.D. in Life Sciences at Sri Sathya Sai University for Human Excellence, focusing on unraveling genetic and environmental factors contributing to CHD through advanced genomic approaches such as GWAS, NGS, and variant screening. His academic background includes a B.Tech. in Biotechnology from GB Pant University of Agriculture and Technology, a DBT-sponsored Postgraduate Diploma in Agricultural Biotechnology from Amity Institute of Biotechnology, and research fellowships across prestigious institutes including JNCASR and IARI Delhi. Professionally, he serves as a Research Officer at Sri Sathya Sai Sanjeevani International Centre for Child Heart Care and Research, where he integrates clinical data analysis with genomic research to explore genotype-phenotype correlations and maternal-perinatal risk factors. His work spans plant biotechnology, nanotechnology integration, and clinical genomics, with multiple peer-reviewed research articles, reviews, and book chapters. Having presented at numerous international conferences and received recognition for his contributions, Mr. Ahamad continues to bridge translational research and clinical application to improve child health outcomes globally.

Profile : Orcid

Featured Publications

  • "Maternal Peri-Conceptional Sleep Quality and Risk of Congenital Heart Disease in Offspring: An Exploratory Case–Control Study"

  • "Developmental Origins of Health and Disease"

  • "Impact of long-term deep freeze storage on human leukocytes viability & DNA extraction: Insights from a resource-limited biorepository"

  • "Navigating Life with Rare Syndromes and Congenital Heart Disease: The Unseen Link"

  • "Is Poor Maternal Sleep Quality in the Periconceptional Period a Risk Factor for Congenital Anomalies in Offspring?"

  • "Systematic molecular view of targets prioritization of congenital heart disease against developmental toxicity"

  • "Paternal Teratogen Exposure and Risk of Congenital Heart Disease in Offspring: A Two-Year Retrospective Observational Study"

  • "Summary of initiatives for treating congenital heart disease: Enhancing quality of life and bridging the knowledge gap"

  • "Computational insights into maternal environmental pollutants and folate pathway regulation"

  • "Isolation and PCR Validation of DNA from Chicory (Cichorium intybus L.) Leaves Using an Optimized CTAB Method to Propel Medicinal Insights"

Hui Shen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Prof. Hui Shen | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

China Pharmaceutical University | China

Author Profile

Google Scholar

🎓 Early Academic Pursuits

Prof. Hui Shen embarked on his scientific journey with a Bachelor’s degree in Bioengineering from Wuhan University of Science and Technology (2008–2012), laying a strong foundation in the life sciences. He then pursued a Ph.D. in Biochemistry and Molecular Biology at the prestigious University of Science and Technology of China (2012–2017). His doctoral thesis focused on structural biology, specifically analyzing proteins in Saccharomyces cerevisiae and Staphylococcus aureus, under the mentorship of Prof. Maikun Teng.

👨‍🔬 Professional Endeavors

Prof. Shen has steadily ascended the academic ladder. After completing his Ph.D., he undertook postdoctoral research at the University of Pennsylvania’s Perelman School of Medicine (2018–2023). Working in Prof. Kathy Fange Liu's lab, he focused on RNA biology and molecular mechanisms in human cells. In 2023, he returned to China and assumed the role of Professor at China Pharmaceutical University in Nanjing, where he continues to contribute to cutting-edge research in the School of Life Science and Technology.

🧬 Contributions and Research Focus

Prof. Shen's research centers on RNA biology, structural biochemistry, and epigenetic regulation. He has delved into RNA helicases, methyltransferases, and RNA-protein interactions, significantly expanding our understanding of sexually dimorphic RNA metabolism, ribosome assembly, and RNA modifications. His work has elucidated mechanisms of phase separation, methylation, and protein structure-function relationships, all of which are vital for both basic science and therapeutic development.

🏆 Accolades and Recognition

Prof. Shen’s scholarly output is remarkable. He has published over a dozen first-author papers in high-impact journals such as Nature Communications, Molecular Cell, Genes & Development, and Journal of Biological Chemistry. His co-authored works also feature in Science Advances, Nature Communications, and ACS Catalysis, underscoring his collaborative and interdisciplinary impact. His presence in top-tier international conferences, including the RNA Society Annual Meeting and the Global Congress of Chinese Biologists, reflects peer recognition of his contributions.

🌍 Impact and Influence

Prof. Shen’s work has influenced fields such as cancer biology, infectious disease research, and epigenetics. For instance, his studies on the DDX3X/DDX3Y helicases and DIMT1 methyltransferases provide novel insights into cell proliferation, translation regulation, and leukemia biology. His findings are not only academically significant but also open avenues for diagnostic and therapeutic strategies targeting RNA and protein modification pathways.

🔮 Legacy and Future Contributions

As a rising star in molecular biology, Prof. Shen is well-positioned to leave a lasting legacy. With a strong publication track record, international training, and a leadership role in China, he is expected to mentor the next generation of scientists while continuing to pioneer research at the interface of structure and function in RNA biology. His work is likely to shape future innovations in biomedicine and pharmaceutical sciences, strengthening China’s global research footprint.

Publications

  • 📄 Specific catalytically impaired DDX3X mutants form sexually dimorphic hollow condensates
    Authors: Owens MC*, Shen H*, Yanas A, Mendoza-Figueroa MS, Lavorando E, Wei XY, Shweta H, Tang HY, Goldman YE, Liu KF
    Journal: Nature Communications
    Year: 2024

  • 📄 Identification of an RNA-binding region in 18S dimethyladenosine methyltransferase DIMT1 essential for proliferation of acute myeloid leukemia cells
    Authors: Gonskikh Y*, Stoute J*, Shen H*, Budinich K, Pingul B, Schultz K, Marmorstein R, Shi JW, Liu KF
    Journal: Genes & Development
    Year: 2023

  • 📄 Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation
    Authors: Shen H*, Yanas A*, Owens MC, Zhang C, Fritsch C, Fare CM, Copley KE, Shorter J, Goldman YE, Liu KF
    Journal: Molecular Cell
    Year: 2022

  • 📄 Human DIMT1 generates N2⁶,6A-dimethylation-containing small RNAs
    Authors: Shen H, Gonskikh Y, Stoute J, Liu KF
    Journal: Journal of Biological Chemistry
    Year: 2021

  • 📄 TET-mediated 5-methylcytosine oxidation in tRNA promotes translation
    Authors: Shen H*, Ontiveros RJ*, Owens MC, Liu MY, Ghanty U, Kohli RM, Liu KF
    Journal: Journal of Biological Chemistry
    Year: 2021

 

Annamaria Russo | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

Published on by Book of Award

Dr. Annamaria Russo | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

University of Messina | Italy

Author Profile

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Orcid

🎓 Early Academic Pursuits

Dr. Annamaria Russo embarked on her scientific journey with a degree in Biological Sciences from the University of Messina in 1997, graduating with top honors (110/110). Her experimental thesis on the functional properties of dolphin hemoglobin marked the beginning of a lifelong interest in comparative and clinical biochemistry. She earned her Professional Biologist Certification and later pursued a Ph.D. in Cellular Biology and Biotechnology in 2014, exploring the metabolic mechanisms and functionality of red blood cells through exogenous molecules.

👩‍🔬 Professional Endeavors

Dr. Russo's career has interwoven research, teaching, and academic mentorship. She began as a research fellow at the Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences (Chibiofaram), focusing on the structural and functional analysis of respiratory proteins in marine organisms. She also held postgraduate research positions in international institutions, including a notable stay at the Institute of Physiology at the Academy of Sciences in Prague. Parallel to her research, she has been a tenured mathematics and science teacher in several secondary schools in Sicily. Since 2006, she has held the title of “Cultore della Materia” in Biochemistry, consistently participating in exam boards and teaching activities.

🧪 Contributions and Research Focus

Dr. Russo's research focuses on biochemistry, erythrocyte metabolism, oxidative stress, protein-ligand interactions, and the thermodynamic characterization of blood components. She has extensively studied the Band 3 protein, hemoglobin functionalities, and interactions in both human and marine organisms. Her studies span from environmental biochemistry to medical applications, including research on red blood cells in diseases like ALS, sickle cell anemia, and the biochemical impact of COVID-19. Her research also explores natural antioxidant compounds and their role in protecting red blood cells, such as polyphenols and caffeine. Additionally, she has contributed to the development of bioplastics and biosensors for environmental applications.

🏅 Accolades and Recognition

With 43 scientific publications, 757 citations, and an H-index of 17, Dr. Russo has established herself as a respected voice in her field. She has served as an editorial board member for high-impact journals such as Stresses and Biology and has been a guest editor for thematic issues in journals like Antioxidants and IJMS (International Journal of Molecular Sciences). She also regularly reviews articles for prominent journals including Molecules and The Journal of Neuroscience Research.

Her research collaborations include prestigious institutions such as:

  • CNR (Rome, Milan, Messina)

  • Catholic University of the Sacred Heart

  • University of Palermo

  • University of Enna “Kore”

  • ARPACAL Calabria

  • University of Cassino

🌍 Impact and Influence

Dr. Russo has mentored numerous undergraduate and graduate students in laboratory settings and thesis projects, shaping the next generation of biochemists. Her work on erythrocyte metabolism and natural antioxidants has implications for clinical diagnostics, environmental monitoring, and neurodegenerative disease prevention. Her multidisciplinary collaborations have allowed her to bridge fundamental science with practical applications.

🔮 Legacy and Future Contributions

With ongoing research in the biochemical implications of environmental stressors, cell metabolism, and sustainable material development, Dr. Russo remains at the forefront of scientific innovation. Her latest conference presentations in 2025 on bioplastic sensors and biochemical characterization of metastasis underscore her commitment to translational research that benefits both health and the environment. Her legacy is that of a passionate scientist and educator dedicated to advancing knowledge in biochemistry while mentoring future scholars and contributing meaningfully to both academic and applied scientific communities.

Publications

📄 Epicatechin Influence on Biochemical Modification of Human Erythrocyte Metabolism and Membrane Integrity
Authors: Russo, Annamaria; Patanè, Giuseppe Tancredi; Laganá, Giuseppina; Tellone, Ester; Putaggio, Stefano
Journal: International Journal of Molecular Sciences
Year: 2024

📄 Crosstalk Between Sickle Cell Disease and Ferroptosis
Authors: Russo, Annamaria; Patanè, Giuseppe Tancredi; Calderaro, Antonella; Tellone, Ester; Putaggio, Stefano
Journal: International Journal of Molecular Sciences
Year: 2025

📄 Emerging Ferroptosis Involvement in Amyotrophic Lateral Sclerosis Pathogenesis: Neuroprotective Activity of Polyphenols
Authors: Russo, Annamaria; Putaggio, Stefano; Tellone, Ester; Barreca, Davide; Patanè, Giuseppe Tancredi
Journal: Molecules
Year: 2025

📄 Canine and Human Red Blood Cells: Biochemical Mechanisms for the Control of Heat Dissipation
Authors: Russo, Annamaria; Patanè, Giuseppe Tancredi; Putaggio, Stefano; Barreca, Davide; Laganà, Giuseppina
Journal: Stresses
Year: 2024

Ester Tellone | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

Published on by Book of Award

Prof. Ester Tellone | Biochemistry, Genetics and Molecular Biology | Excellence in Research Award

University of Messina | Italy

Author Profile

Orcid

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🎓 Early Academic Pursuits

Prof. Ester Tellone began her academic journey with a degree in Biological Sciences (1989) from the University of Messina, graduating with highest honors (110/110 cum laude). She followed this with a second degree in Natural Sciences (1996), again with top marks and a thesis on hemoglobin function in dolphins. Her early research was focused on environmental and marine biology, including dystrophic crises in lake ecosystems.

👩‍🔬 Professional Endeavors

Prof. Tellone embarked on her academic career in 1990 as a Technical Officer at the University of Messina. In 2001, she was appointed as a confirmed researcher and later became an Associate Professor in Biochemistry (BIO/10) in 2018. Since January 2022, she holds the title of Full Professor in the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences at the University of Messina. She has taught various biochemistry courses at undergraduate and postgraduate levels and has been involved in curriculum development, Ph.D. supervision, and departmental governance.

🔬 Contributions and Research Focus

Prof. Tellone's research is centered on red blood cells (erythrocytes) as model systems. Key research themes include:

🧪 Red Blood Cells: Investigating erythrocytes as biosensors and drug delivery systems and exploring amyloid protein aggregation effects.

🧬 Hemoglobin Functionality: Analyzing structural-functional properties and oxygenation dynamics in hemoglobins.

🧫 Band 3 Protein Interactions: Studying its interplay with deoxyhemoglobin and glycolytic enzymes in metabolic regulation.

Her work employs advanced mathematical models and biochemical tools to unravel complex cellular mechanisms, especially oxidative stress, apoptosis, and environmental toxicity in marine and human systems.

🏆 Accolades and Recognition

Prof. Tellone’s excellence has been widely recognized:

🥇 She holds a National Scientific Qualification for Full Professor in General Biochemistry (BIO/10).

📚 She is the author of over 80 scientific articles indexed in Scopus/Web of Science and has contributed chapters to internationally published books.

🧑‍🏫 She has served as Scientific Coordinator for several major EU- and MIUR-funded projects, including INNOVAQUA, 4FRAILTY, ORTHO Line, and SAMOTHRACE.

She is a reviewer for high-impact journals such as Molecules, Journal of Functional Foods, and British Journal of Hematology, and serves on editorial boards of multiple international scientific journals.

🌍 Impact and Influence

Prof. Tellone’s research has made significant contributions in both basic and applied science:

🔬 Her studies on red blood cells and hemoglobin have advanced understanding of diseases like ALS, Alzheimer’s, and diabetes.

🌱 Her environmental research has influenced biotechnological innovations in aquaculture, marine biology, and environmental biosensors.

👩‍🎓 As a mentor and Ph.D. supervisor, she has nurtured the careers of numerous researchers and students in the field of biochemistry.

🌟 Legacy and Future Contributions

Prof. Ester Tellone is a recognized thought leader in red blood cell biochemistry, environmental toxicology, and oxidative stress. Her work bridges molecular biology, environmental sciences, and medical biochemistry, creating interdisciplinary solutions for modern scientific challenges. With her continued involvement in international projects, editorial activities, and mentoring, her influence is set to grow further, shaping the next generation of biochemists and biomedical researchers.

Publications

📄 Exploring Tumor Cell–Platelet Biochemical Interactions by Dielectric Measurements of Blood: A Potential Target for Tumor Detection and Staging
Journal: Biology
Year: 2025 
Authors: Annamaria Russo, Ester Tellone, Francesco Farsaci

📄 Crosstalk Between Sickle Cell Disease and Ferroptosis
Journal: International Journal of Molecular Sciences
Year: 2025 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Antonella Calderaro, Davide Barreca, Ester Tellone, Stefano Putaggio

📄 Emerging Ferroptosis Involvement in Amyotrophic Lateral Sclerosis Pathogenesis: Neuroprotective Activity of Polyphenols
Journal: Molecules
Year: 2025 
Authors: Annamaria Russo, Stefano Putaggio, Ester Tellone, Antonella Calderaro, Santa Cirmi, Giuseppina Laganà, Silvana Ficarra, Davide Barreca, Giuseppe Tancredi Patanè

📄 Epicatechin Influence on Biochemical Modification of Human Erythrocyte Metabolism and Membrane Integrity
Journal: International Journal of Molecular Sciences
Year: 2024 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Giuseppina Laganà, Santa Cirmi, Silvana Ficarra, Davide Barreca, Elena Giunta, Ester Tellone, Stefano Putaggio

📄 Canine and Human Red Blood Cells: Biochemical Mechanisms for the Control of Heat Dissipation
Journal: Stresses
Year: 2024 
Authors: Annamaria Russo, Giuseppe Tancredi Patanè, Stefano Putaggio, Ester Tellone, Silvana Ficarra, Davide Barreca, Giuseppina Laganà