Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Dr. Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Pusan national university | South Korea

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🎓 Early Academic Pursuits

Dr. Dong Hee Kim began his academic journey with a Bachelor of Science in Biology from the University of Ulsan, Korea, in 2004. He continued at the same institution for his M.S.-Ph.D. in Biological Sciences under the mentorship of Professor Byung Ju Lee, completing his doctorate in 2012. His thesis, "Studies on the role of NELL2 in neuroprotection and neural differentiation," laid the foundation for his future research endeavors.

💼 Professional Endeavors

Dr. Kim has held various prestigious positions throughout his career. He is currently a Research Fellow at Pusan National University Hospital since November 2022. Previously, he served as a Research Professor at the University of Ulsan from January 2019 to May 2022, and as a Research Fellow at the same university from January 2015 to October 2016. His early postdoctoral work was conducted at UNIST from March 2013 to December 2014.

🧪 Contributions and Research Focus

Dr. Kim's research primarily revolves around neuroprotection, neural differentiation, and the molecular mechanisms underlying neurodegenerative diseases. His notable grants include funding from WISET for studying the function of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the brain, and multiple grants from the NRF of Korea, including studies on TonEBP function in hypothalamic leptin resistance and its role in degenerative brain disorders.

🏅 Accolades and Recognition

Throughout his career, Dr. Kim has received significant recognition for his contributions to biomedical research. His projects have been supported by prestigious grants, highlighting the impact and importance of his work in understanding brain functions and disorders. His research has also resulted in numerous publications in high-impact journals, further establishing his reputation in the field.

🌟 Impact and Influence

Dr. Kim's research has significantly advanced the understanding of neural mechanisms and their implications in neurodegenerative diseases. His work on the transcription regulation of key genes involved in brain function and inflammation has provided new insights into potential therapeutic targets. His publications have been widely cited, indicating the influence of his research on the scientific community.

📚 Legacy and Future Contributions

Dr. Kim's ongoing research continues to push the boundaries of our understanding of the brain. His current projects, funded by substantial grants, promise to uncover new mechanisms of brain function and disease. As he progresses in his career, Dr. Kim is poised to make further groundbreaking discoveries that will contribute to the field of biomedical science and technology.

 

Publications 📘

📄 Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Transcription Regulation of AgRP and POMC Genes

👩‍🔬 Authors: Kim DH*, Lee MJ, Kang D, Khang AR, Bae JH, Kim JY, Kim SH, Kang YH, Yi D.

📕 Journal: Curr Issues Mol Biol.

📅 Year: 2024


📄 Bridging Energy Need and Feeding Behavior: The Impact of eIF2α Phosphorylation in AgRP Neurons

👩‍🔬 Authors: Kim KK, Lee TH, Park BS, Kang D, Kim DH, Jeong B, Kim JW, Yang HR, Kim HR, Jin S, Back SH, Park JW, Kim JG, Lee BJ.

📕 Journal: Diabetes

📅 Year: 2023


📄 Sirtuin 1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to Energy Deficiency Response

👩‍🔬 Authors: Kang D, Yang HR, Kim DH, Kim KK, Jeong B, Park BS, Park JW, Kim JG, Lee BJ.

📕 Journal: Int J Mol Sci.

📅 Year: 2023


📄 Inhibition of LPAR1 Signaling in PDLSCs Reduces the Inflammatory Paracrine Effect on Primary Astrocyte Cells

👩‍🔬 Authors: Kim DH*, Seo EJ*, Kim YH, Jang IH.

📕 Journal: Int J Oral Biol.

📅 Year: 2022


📄 Transcriptional Regulatory Role of NELL2 in Preproenkphalin Gene Expression

👩‍🔬 Authors: Ha CM*, Kim DH*, Lee TH, Kim HR, Choi JI, Kim Y, Kang DS, Park JW, Oieda S, Jeong JK, Lee BJ.

📕 Journal: Mol Cells

📅 Year: 2022

Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Mr. Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Hebrew University of Jerusalem | Israel

Author Profile

Scopus

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Early Academic Pursuits

Mr. Jairus Nandwa embarked on his academic journey with a Bachelor of Technology in Industrial Microbiology and Biotechnology from The Technical University of Mombasa, Kenya. He further pursued a Master of Science in Biosciences at COMSATS University Islamabad, Pakistan, and is currently pursuing a PhD in Genetics at The Hebrew University of Jerusalem, focusing on circular RNAs, SNORDS, and miRNAs in cancer under the guidance of Professor Ruth Sperling.

Professional Endeavors

With a robust academic background, Mr. Nandwa engaged in various research experiences, including his role as a Graduate Student/Research Student at the Cancer Genetics and Epigenetics Lab, COMSATS University, Pakistan. He also served as a Laboratory Analyst during his BTech internship at the Regional Veterinary Investigation Laboratory, Kenya.

Contributions and Research Focus

Mr. Nandwa's research interests span non-coding RNAs in gene expression regulation, tumor microenvironment, biomarker/therapeutic discovery, DNA repair mechanisms, and biological data analysis. He has authored several publications and presented his research at esteemed conferences globally.

Accolades and Recognition

His notable publications include research on miRNA-4716–3p and its association with blood cancer pathogenesis, earning recognition in Non-Coding RNA Research. He has also received awards such as the Queen Elizabeth Commonwealth Scholarship and First Class Honors in BTech Industrial Microbiology and Biotechnology.

Impact and Influence

Mr. Nandwa's contributions extend beyond academia, with leadership roles in cancer education initiatives and community service engagements. His research and volunteer efforts demonstrate a commitment to advancing scientific knowledge and addressing societal challenges.

Legacy and Future Contributions

As Mr. Nandwa continues his doctoral studies and research pursuits, his dedication to understanding the intricacies of cancer biology and contributing to innovative solutions positions him as a promising researcher in the field of genetics. His leadership, academic achievements, and community impact foreshadow a legacy of scientific excellence and social responsibility.

Notable Publications

miR-4716–3p and the target AKT2 Gene/rs2304186 SNP are associated with blood cancer pathogenesis in Pakistani population 2024

In silico analysis of RPS4X (X-linked ribosomal protein) with active components from black seed (Nigella sativa) for potential treatment of multiple sclerosis 2024

Therapeutic capability of selected medicinal plants' bioactive constituents against the mutant ovarian TP53 gene; a computational approach 2023

Targeting allosteric sites on PDK-1 and PLK-1 with bioactive compounds from Daucus carota as a potential therapy for triple-negative breast cancer 2023

 

 

 

Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

National and Kapodistrian University of Athens | Greece

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Google Scholar

Early Academic Pursuits

Andreas Agathangelidis initiated his scientific journey at Thessaloniki's "G. Papanikolaou" hospital, delving into Chronic Lymphocytic Leukemia (CLL) and antigens for his diploma thesis. Subsequently, his Ph.D. at Aristotle University focused on immunogenetics in B-cell malignancies.

Professional Endeavors

Agathangelidis conducted groundbreaking studies during his Ph.D., notably refining CLL molecular classification using a sizable patient cohort. His postdoctoral research at San Raffaele Scientific Institute, Milan, explored CLL and Monoclonal B lymphocytosis (MBL) under Professor Paolo Ghia, broadening his expertise in advanced genetic methodologies.

Contributions and Research Focus

Significant contributions include expansive studies on CLL patients and the largest worldwide series on Mantle Lymphoma (MCL), emphasizing the role of antigens in disease progression. He conducted diverse immunoprofiling studies, exploring gene rearrangements and subtyping based on immunogenetics, oncogenetics, and immunophenotype integration.

Accolades and Recognition

Agathangelidis' pioneering research secured recognition, including fellowships from the HFRI Foundation and industry funding from Gilead Sciences. His leadership in the "CLLon" project, studying the B cell receptor's role in CLL and MBL development, represents a significant achievement in cancer genetics.

Impact and Influence

His work has significantly challenged prevailing views in disease mechanisms, refining classifications, and paving the way for targeted therapies for B-cell malignancies. The extensive studies he led have had a substantial impact on understanding disease ontogeny and the development of potential treatments.

Legacy and Future Contributions

Currently an Assistant Professor at the National and Kapodistrian University of Athens, Agathangelidis continues his research using advanced NGS technologies. His focus on elucidating the B cell receptor's role in CLL and MBL development through deep sequencing and bioinformatics is poised to bring forth notable advancements in cancer genetics and potential therapeutic avenues.

Notable Publications

Recurrent mutations refine prognosis in chronic lymphocytic leukemia 2014 (219)

A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study 2015 (179)

Antigen receptor stereotypy in chronic lymphocytic leukemia 2016 (99)