Simeon Ikechukwu Egba | Biochemistry, Genetics and Molecular Biology | Editorial Board Member

Dr. Simeon Ikechukwu Egba | Biochemistry, Genetics and Molecular Biology | Editorial Board Member

Kampala International University | Uganda

Author Profile

Scopus

Orcid

Early Academic Pursuits 📚

Dr. Simeon Ikechukwu Egba’s academic journey began with his foundational education in Nigeria. After completing his secondary education at Community Secondary School, Eha-ohuala and Special Science School, Igbeagu, he pursued his undergraduate studies at the University of Nigeria, Nsukka, where he earned a Bachelor’s degree in Biochemistry in 2000. His academic curiosity and dedication to biochemistry led him to continue his studies at the same institution, earning a Master's degree in 2010 and later a Ph.D. in Biochemistry in 2014. His commitment to furthering his expertise in medical laboratory sciences was also demonstrated through studies at Nnamdi Azikiwe University Teaching Hospital-Nnewi.

Professional Endeavors 🏫

Dr. Egba's professional journey in academia spans over twelve years, during which he has held numerous positions that showcase his leadership and commitment to research and education. He has served as a lecturer in Biochemistry at various institutions, including Michael Okpara University of Agriculture, Umudike, and currently at Kampala International University, Uganda. His responsibilities have included teaching courses in biochemistry, overseeing laboratory sessions, and coordinating various academic functions such as the Student Industrial Work Experience Scheme (SIWES). Additionally, he has taken on key administrative roles, including being a member of the University Senate, and has led projects in research and curriculum development.

Contributions and Research Focus 🔬

Dr. Egba’s research interests are diverse and impactful, focusing on medical biochemistry, natural products, immune-modulation, endocrinology, and biochemical toxicology. His research has not only expanded the scientific understanding of these fields but has also contributed to real-world applications, such as exploring the immune-modulatory effects of herbal extracts and investigating glucose transport enhancement. He has made significant contributions to diabetes research, with several studies on anti-diabetic poly-herbal formulas. His scholarly work includes over 70 publications and successful supervision of 18 postgraduate students, many of whom have gone on to have successful academic careers.

Accolades and Recognition 🏅

Dr. Egba's academic excellence has earned him recognition within the scientific community. He has received multiple research grants, including those from the TETFUND, for projects that focus on diabetes and immunological responses. His dedication to his field is evident not only in his numerous publications but also in his role as a mentor, guiding over 150 undergraduate students through their research projects, many of whom have received scholarships to pursue postgraduate studies worldwide. Dr. Egba is an active member of the Nigerian Society of Biochemistry and Molecular Biology (NSBMB) and the Association of Medical Laboratory Scientists of Nigeria (AMLSN).

Impact and Influence 🌍

Dr. Egba’s impact extends beyond academia through his direct contributions to research and the development of future scholars. His research on the biochemical effects of natural products has influenced studies on immune-modulation and endocrinology, providing valuable insights into how natural compounds can influence human health. He has also played a pivotal role in improving the quality of laboratory practices and biochemistry education. His students, both undergraduate and postgraduate, continue to carry forward his legacy in research and academia, furthering his influence globally.

Legacy and Future Contributions 🌟

Dr. Egba’s future contributions are poised to further cement his legacy as a leading academic and researcher. His ongoing research projects aim to continue advancing the understanding of the biochemical pathways in diseases such as diabetes, and his work with poly-herbal formulations could have significant therapeutic implications. As he trains the next generation of biochemists and medical laboratory scientists, Dr. Egba’s influence will continue to shape the future of research and medical science, particularly in the fields of immunology and endocrinology.

Publication


  • 📜 Effects of exposure to volatile organic compounds (VOCs) content from paint on automobile paint workers in Nsukka, South Eastern Nigeria
    Authors: Ogbodo, J.O., Egba, S.I., Ogbodo, C.G., Onwurah, I.E., Njoku, O.U.
    Journal: Heliyon
    Year: 2024

  • 📜 Understanding apoptosis in sickle cell anemia patients: Mechanisms and implications
    Authors: Obeagu, E.I., Ubosi, N.I., Obeagu, G.U., Egba, S.I., Bluth, M.H.
    Journal: Medicine (United States)
    Year: 2024

  • 📜 Evaluation of fertility hormones and biochemical stress initiated by toxicant in diet prepared with fish smoked with polyethylene (plastic) materials as a fuel source
    Authors: Uhuo, E.N., Egba, S.I., Alaebo, P.O., Obike, C.A., Ede, I.S.
    Journal: Comparative Clinical Pathology
    Year: 2023

  • 📜 Antioxidative properties of Adansonia digitata L. (baobab) leaf extract exert protective effect on doxorubicin-induced cardiac toxicity in Wistar rats
    Authors: Uhuo, E.N., Egba, S.I., Nwuke, P.C., Obike, C.A., Kelechi, G.K.
    Journal: Clinical Nutrition Open Science
    Year: 2022

  • 📜 Renoprotective effects of Adansonia digitata leaf extract on renal function and histopathological changes in vancomycin-induced nephrotoxicity in Wistar rats
    Authors: Uhuo, E.N., Egba, S.I., Nwuke, P.N., Odinamadu, H.
    Journal: Comparative Clinical Pathology
    Year: 2022

 

Kercia Cruz | Agricultural and Biological Sciences | Best Researcher Award

Dr. Kercia Cruz | Agricultural and Biological Sciences | Best Researcher Award

Federal University of Bahia | Brazil

Author Profile

Orcid

Early Academic Pursuits 🎓

Dr. Kercia Cruz began her academic journey with a degree in Biological Sciences from Universidade Federal da Bahia in 2014. She furthered her studies with a master’s in Biotechnology in Health and Investigative Medicine from Fundação Oswaldo Cruz, graduating in 2017. Her research during this period focused on leishmaniasis and the role of macrophages in infection. She then pursued a Ph.D. in Biotechnology in Health and Investigative Medicine at Fundação Oswaldo Cruz, completing it in 2023. Her doctoral research centered on the development of nanomedicines for treating leishmaniasis, particularly focusing on the protein translocator HSP90.

Professional Endeavors 🔬

Dr. Cruz has worked extensively in the field of general biology with a specialization in leishmaniasis and macrophage infections. Her professional experience includes positions at Universidade Federal da Bahia and Centro Universitário SENAI CIMATEC, where she has contributed significantly to research and education. Her roles involved working on projects related to the therapeutic potential of nanoparticles and the molecular mechanisms of leishmaniasis. She has also participated in various internships and short-term research activities across Brazil and Portugal. 🌍

Contributions and Research Focus 🧫

Dr. Cruz’s research primarily focuses on leishmaniasis, particularly the use of nanomedicines and the role of protein translocators like HSP90 in combating infection. She has been involved in several research projects exploring the potential of nanoparticle-based therapies for leishmaniasis and other infectious diseases. Her work also includes studying the molecular and cellular aspects of macrophage interactions with pathogens, contributing to the development of innovative treatment strategies. 🧪

Accolades and Recognition 🏅

Dr. Cruz has received notable recognition for her research contributions. In 2022, she was awarded an honorable mention for her work on polymeric nanoparticles containing amphotericin B at Embrapa. Additionally, she received a commendation in 2020 for her ongoing doctoral thesis from the Program of Postgraduate Studies in Biotechnology in Health and Investigative Medicine at Fiocruz. These accolades highlight her significant impact in her field. 🏆

Impact and Influence 🌟

Dr. Cruz’s research has advanced the understanding of leishmaniasis and the potential of nanomedicines in treating this disease. Her work on nanomedicine and protein translocators has provided valuable insights into innovative treatment approaches, potentially improving patient outcomes and contributing to global health solutions. Her contributions have influenced both academic research and practical applications in biotechnology. 🌐

Legacy and Future Contributions 🚀

Looking forward, Dr. Cruz aims to continue her work on developing novel therapeutic strategies for infectious diseases. Her future research will likely focus on expanding the use of nanomedicines and exploring new avenues in molecular biology to address pressing health challenges. Her dedication to advancing scientific knowledge and improving treatment options ensures that her legacy will continue to benefit the field of biotechnology and beyond.

 

Publications 📚


  • 📝Intraperitoneal Administration of 17-DMAG as an Effective Treatment against Leishmania braziliensis Infection in BALB/c Mice: A Preclinical Study
    • Authors: Kercia P. Cruz, Antonio L. O. A. Petersen, Marina F. Amorim, Alan G. S. F. Pinho, Luana C. Palma, Diana A. S. Dantas, Mariana R. G. Silveira, Carine S. A. Silva, Ana Luiza J. Cordeiro, Izabella G. Oliveira, Gabriella B. Pita, Bianca C. A. Souza, Gilberto C. Bomfim, Cláudia I. Brodskyn, Deborah B. M. Fraga, Isadora S. Lima, Maria B. R. De_Santana, Helena M. P. Teixeira, Juliana P. B. De_Menezes, Washington L. C. Santos
    • Journal: Pathogens
    • Year: 2024

  • 📝Development and Characterization of PLGA Nanoparticles Containing 17-DMAG, an Hsp90 Inhibitor
    • Authors: Kercia P. Cruz, Beatriz F. C. Patricio, Vinícius C. Pires, Marina F. Amorim, Alan G. S. F. Pinho, Helenita C. Quadros, Diana A. S. Dantas, Marcelo H. C. Chaves, Fabio R. Formiga, Helvécio V. A. Rocha, Patrícia S. T. Veras
    • Journal: Frontiers in Chemistry
    • Year: 2021

  • 📝Microbiologia no cotidiano: proposta de ensino por investigação de baixo custo
    • Authors: K. P. Cruz, G. L. Nery, A. A. D. Reboucás, P. R. Dantas-Silva, J. S. Cruz, C. G. S. Andrade, R. M. L. Rahimy
    • Journal: Atas de Ciências da Saúde
    • Year: 2019

  • 📝In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
    • Authors: C. E. S. Guedes, B. R. S. Dias, A. L. O. A. Petersen, Kercia P. Cruz, N. J. Almeida, D. R. Andrade, J. P. B. Menezes, V. M. Borges, P. S. T. Veras
    • Journal: Memórias do Instituto Oswaldo Cruz
    • Year: 2018