Mehlika Dilek Altıntop | Pharmacology, Toxicology and Pharmaceutical Science | Women Research Award

Prof Dr. Mehlika Dilek Altıntop | Pharmacology, Toxicology and Pharmaceutical Science | Women Research Award

Anadolu University | Turkey

Author Profile

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Early Academic Pursuits 🎓

Prof. Dr. Mehlika Dilek Altıntop began her academic journey at İkieylül Elementary School (1991-1996) and continued at Eskişehir Anatolian High School (1996-2003). She pursued her undergraduate studies at Anadolu University, Faculty of Pharmacy (2003-2007). Following this, she completed her Master’s degree (with thesis) at Anadolu University, Graduate School of Health Sciences, Department of Pharmaceutical Chemistry (2007-2009). Her doctoral studies were also undertaken at Anadolu University, focusing on Pharmaceutical Chemistry (2009-2012).

Professional Endeavors 🏢

Dr. Altıntop’s professional career began as a Research Assistant at Anadolu University, Faculty of Pharmacy (2010-2012). She advanced to Research Assistant Doctor (2012-2014) and subsequently to Assistant Professor Doctor (2014-2015). She earned her position as Associate Professor Doctor (2015-2020) and was promoted to Professor Doctor (2020-present) at Anadolu University, Faculty of Pharmacy. Her administrative roles include serving as the Erasmus/Farabi/Mevlana Assistant Coordinator (2013-2014), Associate Director of Anadolu University Graduate School of Health Sciences (2014-2017 and 2023), and Quality Coordinator (2022-2023).

Contributions and Research Focus 🔬

Prof. Dr. Altıntop’s research predominantly focuses on pharmaceutical chemistry, medicinal chemistry, and drug development. She has made significant contributions to the synthesis and evaluation of novel compounds with therapeutic potential. Her work includes the development of dual EGFR and Akt inhibitors and small-molecule inhibitors targeting cancer therapy. She has also explored novel metabolic enzyme inhibitors and aldose reductase inhibitors.

Accolades and Recognition 🏆

Dr. Altıntop has received numerous awards for her academic and research achievements:

  • Anadolu University Faculty of Pharmacy Championship Award (2007)
  • Graduate Scholarship from The Scientific and Technological Research Council of Turkey (2007-2009)
  • Anadolu University Science and Technology Encouragement Award (2014)
  • Anadolu University Gold Article Performance Award (2015)
  • Turkish Pharmacists’ Association Academy of Pharmacy Encouragement Award (2019)
  • Outstanding Woman Researcher in Pharmaceutical Chemistry Award (VIWA 2021)
  • ISIF'21 Silver Medal for invention (2021)
  • Top Cited Article Awards (2021-2023)

Impact and Influence 🌟

Dr. Altıntop’s work has had a substantial impact on the field of pharmaceutical chemistry, particularly in the development of novel therapeutic agents for cancer and other diseases. Her role as an Associate Editor and Guest Editor in prestigious journals, as well as her involvement in international scientific committees, highlights her influence and leadership in the field.

Legacy and Future Contributions 🌐

Prof. Dr. Altıntop’s contributions continue to shape the future of pharmaceutical research and drug development. Her ongoing work in medicinal chemistry and her role in mentoring the next generation of researchers underscore her lasting legacy in advancing science and improving healthcare outcomes.

 

Publications

  • 📜Design, Synthesis, and Biological Evaluation of a New Series of Imidazothiazole-Hydrazone Hybrids as Dual EGFR and Akt Inhibitors for NSCLC Therapy
    Authors: Mehlika Dilek Altıntop, İpek Ertorun, Gülşen Akalın Çiftçi, Ahmet Özdemir
    Journal: European Journal of Medicinal Chemistry
    Year: 2024

 

  • 📜Design, Synthesis, and In Vivo Evaluation of a New Series of Indole-Chalcone Hybrids as Analgesic and Anti-Inflammatory Agents
    Authors: Baramaki, I., Altıntop, M.D., Arslan, R., Hasan, A., Bektaş Türkmen, N.
    Journal: ACS Omega
    Year: 2024

 

  • 📜Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents
    Authors: Altıntop, M.D., Cantürk, Z., Özdemir, A.
    Journal: ACS Omega
    Year: 2023

 

  • 📜Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy
    Authors: Erdoğan, B., Altıntop, M.D., Akalın Çiftçi, G., Özdemir, A., Ece, A.
    Journal: ACS Omega
    Year: 2023

 

  • 📜A New Series of Hydrazones as Small-Molecule Aldose Reductase Inhibitors
    Authors: Altıntop, M.D., Demir, Y., Türkeş, C., Beydemir, Ş., Özdemir, A.
    Journal: Archiv der Pharmazie
    Year: 2023

 

  • 📜A New Series of Thiazole-Hydrazone Hybrids for Akt-Targeted Therapy of Non-Small Cell Lung Cancer
    Authors: Orujova, T., Ece, A., Akalın Çiftçi, G., Özdemir, A., Altıntop, M.D.
    Journal: Drug Development Research
    Year: 2023

Ahmet Özdemir | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Prof Dr. Ahmet Özdemir | Pharmacology, Toxicology and Pharmaceutical Science | Best Researcher Award

Anadolu University | Turkey

Author Profile

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Early Academic Pursuits 🎓

Prof. Dr. Ahmet Özdemir's academic journey began at Salihli Cumhuriyet Elementary School (1978-1983), followed by Salihli 50. Yıl Secondary School (1983-1986) and Salihli High School (1986-1989). His passion for pharmacy led him to Anadolu University Faculty of Pharmacy, where he completed his undergraduate studies (1990-1994). He pursued further education at the Graduate School of Health Sciences, Department of Pharmaceutical Chemistry at Anadolu University, earning a Master's degree (1995-1996) and a Doctor's degree (1996-2004).

Professional Endeavors 💼

Prof. Dr. Özdemir's professional career commenced at Anadolu University as a Research Assistant (1997-2004). He progressed to Research Assistant Doctor (2004-2005), Lecturer (2005-2007), and Assistant Professor Doctor (2007-2010). His dedication and expertise earned him the title of Associate Professor Doctor (2010-2015), and he has been serving as a Professor Doctor since 2015.

Contributions and Research Focus 🔍

Prof. Dr. Özdemir's research is marked by significant contributions to pharmaceutical chemistry. His Master's thesis focused on "The studies on the synthesis, structure elucidations and determination of physicochemical parameters of some 2-substituted-1H-phenantro[9,10-d]imidazole compounds," under the supervision of Prof. Dr. İlhan Işıkdağ. His PhD thesis, supervised by Prof. Dr. Gülhan Turan, investigated the "Synthesis of some 1-[(N,N-disubstituted-thiocarbonylthio)acetyl]-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and their antifungal, antibacterial activities."

Accolades and Recognition 🏅

Prof. Dr. Özdemir's work has been widely recognized, earning him numerous awards:

  • Anadolu University Article Performance Award (2014, 2016, 2017, 2018, 2020)
  • Anadolu University Gold Article Performance Award (2015)
  • Anadolu University Platinum Article Performance Award (2015)
  • Anadolu University Academic Success Award (2019)
  • ISIF'21 Silver Medal for the invention "Targeted Novel Triazolothiadiazine Derivatives for The Treatment of Lung Cancer" (2021)

Impact and Influence 🌟

Prof. Dr. Özdemir's impact extends beyond research. He has held key administrative roles, including Associate Director of Anadolu University Yunus Emre Vocational School (2011-2014) and Vice Academic Director of the Anadolu University Open Education Faculty, Department of Health Administration (2015-present). His mentorship has guided many students, as evidenced by his supervision of numerous master’s and doctoral dissertations.

Legacy and Future Contributions 🚀

Prof. Dr. Özdemir’s legacy is built on his unwavering commitment to advancing pharmaceutical chemistry. His innovative research, administrative leadership, and dedication to education have left an indelible mark on Anadolu University and the broader scientific community. As he continues his work, Prof. Dr. Özdemir is poised to make further groundbreaking contributions that will shape the future of pharmaceutical sciences.

 

Publications

📜Title: Design, Synthesis, and Biological Evaluation of a New Series of Imidazothiazole-Hydrazone Hybrids as Dual EGFR and Akt Inhibitors for NSCLC Therapy
Authors: Mehlika Dilek Altıntop, İpek Ertorun, Gülşen Akalın Çiftçi, Ahmet Özdemir
Journal: European Journal of Medicinal Chemistry
Year: 2024

📜Title: Design, Synthesis, and In Vivo Evaluation of a New Series of Indole-Chalcone Hybrids as Analgesic and Anti-Inflammatory Agents
Authors: Baramaki, I., Altıntop, M.D., Arslan, R., Hasan, A., Bektaş Türkmen, N.
Journal: ACS Omega
Year: 2024

📜Title: Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents
Authors: Altıntop, M.D., Cantürk, Z., Özdemir, A.
Journal: ACS Omega
Year: 2023

📜Title: Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy
Authors: Erdönmez, B., Altıntop, M.D., Akalın Çiftçi, G., Özdemir, A., Ece, A.
Journal: ACS Omega
Year: 2023

📜Title: A New Series of Hydrazones as Small-Molecule Aldose Reductase Inhibitors
Authors: Altıntop, M.D., Demir, Y., Türkeş, C., Beydemir, Ş., Özdemir, A.
Journal: Archiv der Pharmazie
Year: 2023

📜Title: A New Series of Thiazole-Hydrazone Hybrids for Akt-Targeted Therapy of Non-Small Cell Lung Cancer
Authors: Orujova, T., Ece, A., Akalın Çiftçi, G., Özdemir, A., Altıntop, M.D.
Journal: Drug Development Research
Year: 2023