Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Prof. Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Duke Kunshan University | China

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🎓 Early Academic Pursuits

Prof. Hyun Min Kim's journey in the scientific realm began with a Bachelor of Science in Life Science from Hanyang University, Seoul, South Korea, in 1997. This foundational phase nurtured his interest in microbiology, leading to a Master of Science in Life Science (Microbiology) from the same institution in 1999. His academic ascent culminated in a Ph.D. in Applied Biology (Genetics and Molecular Cell Biology) at Georgia Institute of Technology, USA, in 2009, where he explored genome instability, tri-nucleotide repeats, and their genetic implications. This solid academic grounding propelled him toward groundbreaking discoveries.

👨‍🔬 Professional Endeavors

Prof. Kim’s illustrious career spans continents and decades, beginning as a Chief Research Scientist at Hanyang University Medical School, focusing on cytokine profiling and toll-like receptor proteins. His time as a Research Assistant and later a Post-doctoral Fellow at Harvard Medical School cemented his expertise in genome editing and DNA damage repair mechanisms.
His roles as Associate Professor at Tianjin University and Duke Kunshan University underscore his contributions to epigenetics and the development of CRISPR-Cas9 systems. Currently, he serves as an Associate Professor of the Practice at Duke University, advancing molecular biology through cutting-edge research on histone demethylases and DNA damage repair.

🔬 Contributions and Research Focus

Prof. Kim's research revolves around epigenetic regulation and genome editing. He has made pivotal contributions to understanding histone demethylases' roles in DNA damage repair and cancer pathways. His work on CRISPR-Cas9 has refined genome editing techniques, particularly in C. elegans, enabling advances in genetic and therapeutic research. His publications, spanning high-impact journals like Biomolecules, Frontiers in Genetics, and Nature Communications, highlight his dedication to elucidating molecular mechanisms influencing genetic stability and cancer development.

🏆 Accolades and Recognition

Prof. Kim's academic excellence has been consistently recognized. From early scholarships at Hanyang University to the prestigious Sarstedt® Graduate Student Award for his Ph.D. accomplishments, his journey is marked by accolades. He received the Faculty Teaching Award at Tianjin University and multiple travel and mentorship awards, showcasing his dual strengths as a researcher and educator. His innovative work has also attracted significant funding, including grants from the National Natural Science Foundation of China and the Kunshan Shuangchuang Grant, totaling millions in support for his transformative projects.

🌟 Impact and Influence

Prof. Kim's efforts have shaped the scientific and academic communities. His leadership roles, such as organizing journal clubs at Harvard Medical School and contributing to editorial boards like Life Journal and Jove Journal, underscore his influence. As a mentor, he has guided budding researchers and students, exemplified by his award for mentoring undergraduates at Georgia Tech. His findings in genome stability, CRISPR-Cas9, and epigenetics continue to inspire advancements in genetic engineering and cancer therapy.

✨ Legacy and Future Contributions

With an eye on the future, Prof. Kim remains committed to unraveling the mysteries of molecular genetics and epigenetics. His work lays a foundation for next-generation cancer therapeutics and genome editing platforms. As a leader in both teaching and research, his legacy will undoubtedly endure, fostering innovation and collaboration in life sciences globally.

 

Publications

📄 Torenia sp. Extracts Contain Multiple Potent Antitumor Compounds with Nematocidal Activity, Triggering an Activated DNA Damage Checkpoint and Defective Meiotic Progression

  • Author: Meng, Q., Borris, R.P., Kim, H.-M.
  • Journal: Pharmaceuticals
  • Year: 2024

📄 Exploring the Impact of Onobrychis cornuta and Veratrum lobelianum Extracts on C. elegans: Implications for MAPK Modulation, Germline Development, and Antitumor Properties

  • Author: Meng, Q., Pathak, N., Ren, X., Borris, R.P., Kim, H.-M.
  • Journal: Nutrients
  • Year: 2024

📖 LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond

  • Author: Kim, H.-M., Liu, Z.
  • Journal: Biomolecules
  • Year: 2024

📖 Experimental Insights into the Interplay between Histone Modifiers and p53 in Regulating Gene Expression

  • Author: Kim, H.-M., Zheng, X., Lee, E.
  • Journal: International Journal of Molecular Sciences,
  • Year:  2023

📖 A Decade of CRISPR-Cas Genome Editing in C. elegans

  • Author: Kim, H.-M., Hong, Y., Chen, J.
  • Journal:  International Journal of Molecular Sciences
  • Year:  2022

 

Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

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Dr. Dong Hee Kim | Biochemistry, Genetics and Molecular Biology | Best Research Award

Pusan national university | South Korea

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🎓 Early Academic Pursuits

Dr. Dong Hee Kim began his academic journey with a Bachelor of Science in Biology from the University of Ulsan, Korea, in 2004. He continued at the same institution for his M.S.-Ph.D. in Biological Sciences under the mentorship of Professor Byung Ju Lee, completing his doctorate in 2012. His thesis, "Studies on the role of NELL2 in neuroprotection and neural differentiation," laid the foundation for his future research endeavors.

💼 Professional Endeavors

Dr. Kim has held various prestigious positions throughout his career. He is currently a Research Fellow at Pusan National University Hospital since November 2022. Previously, he served as a Research Professor at the University of Ulsan from January 2019 to May 2022, and as a Research Fellow at the same university from January 2015 to October 2016. His early postdoctoral work was conducted at UNIST from March 2013 to December 2014.

🧪 Contributions and Research Focus

Dr. Kim's research primarily revolves around neuroprotection, neural differentiation, and the molecular mechanisms underlying neurodegenerative diseases. His notable grants include funding from WISET for studying the function of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the brain, and multiple grants from the NRF of Korea, including studies on TonEBP function in hypothalamic leptin resistance and its role in degenerative brain disorders.

🏅 Accolades and Recognition

Throughout his career, Dr. Kim has received significant recognition for his contributions to biomedical research. His projects have been supported by prestigious grants, highlighting the impact and importance of his work in understanding brain functions and disorders. His research has also resulted in numerous publications in high-impact journals, further establishing his reputation in the field.

🌟 Impact and Influence

Dr. Kim's research has significantly advanced the understanding of neural mechanisms and their implications in neurodegenerative diseases. His work on the transcription regulation of key genes involved in brain function and inflammation has provided new insights into potential therapeutic targets. His publications have been widely cited, indicating the influence of his research on the scientific community.

📚 Legacy and Future Contributions

Dr. Kim's ongoing research continues to push the boundaries of our understanding of the brain. His current projects, funded by substantial grants, promise to uncover new mechanisms of brain function and disease. As he progresses in his career, Dr. Kim is poised to make further groundbreaking discoveries that will contribute to the field of biomedical science and technology.

 

Publications 📘

📄 Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Transcription Regulation of AgRP and POMC Genes

👩‍🔬 Authors: Kim DH*, Lee MJ, Kang D, Khang AR, Bae JH, Kim JY, Kim SH, Kang YH, Yi D.

📕 Journal: Curr Issues Mol Biol.

📅 Year: 2024

📄 Bridging Energy Need and Feeding Behavior: The Impact of eIF2α Phosphorylation in AgRP Neurons

👩‍🔬 Authors: Kim KK, Lee TH, Park BS, Kang D, Kim DH, Jeong B, Kim JW, Yang HR, Kim HR, Jin S, Back SH, Park JW, Kim JG, Lee BJ.

📕 Journal: Diabetes

📅 Year: 2023

📄 Sirtuin 1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to Energy Deficiency Response

👩‍🔬 Authors: Kang D, Yang HR, Kim DH, Kim KK, Jeong B, Park BS, Park JW, Kim JG, Lee BJ.

📕 Journal: Int J Mol Sci.

📅 Year: 2023

📄 Inhibition of LPAR1 Signaling in PDLSCs Reduces the Inflammatory Paracrine Effect on Primary Astrocyte Cells

👩‍🔬 Authors: Kim DH*, Seo EJ*, Kim YH, Jang IH.

📕 Journal: Int J Oral Biol.

📅 Year: 2022

📄 Transcriptional Regulatory Role of NELL2 in Preproenkphalin Gene Expression

👩‍🔬 Authors: Ha CM*, Kim DH*, Lee TH, Kim HR, Choi JI, Kim Y, Kang DS, Park JW, Oieda S, Jeong JK, Lee BJ.

📕 Journal: Mol Cells

📅 Year: 2022

Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Mr. Jairus Nandwa | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Hebrew University of Jerusalem | Israel

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Early Academic Pursuits

Mr. Jairus Nandwa's academic journey commenced with a Bachelor's in Industrial Microbiology and Biotechnology from The Technical University of Mombasa, Kenya. He pursued his passion further with a Master's in Biosciences from COMSATS University Islamabad, Pakistan, where he delved into cancer genetics. Currently, he is pursuing a Ph.D. in Genetics at The Hebrew University of Jerusalem, focusing on circular RNAs, SNORDs, and miRNAs in cancer under the guidance of Professor Ruth Sperling.

Professional Endeavors

Jairus has garnered diverse professional experiences, from his tenure as a Laboratory Analyst at the Regional Veterinary Investigation Laboratory, Kenya, to his role as the Head of Public Needs Research at the Integrated Cancer Research Foundation of Kenya. He has contributed significantly to cancer education and research, both as a volunteer and in leadership positions, demonstrating his commitment to advancing cancer management in Kenya.

Contributions and Research Focus

With a strong background in biochemistry, genetics, and molecular biology, Jairus has dedicated his research efforts to elucidating the roles of non-coding RNAs in gene expression regulation, tumor microenvironment, biomarker discovery, and DNA repair mechanisms. His research spans both experimental and computational domains, aiming to unravel the complexities of cancer genetics and improve therapeutic strategies.

Accolades and Recognition

Jairus's contributions to the field of cancer genetics have been recognized internationally. He has been awarded prestigious scholarships, including the Queen Elizabeth Commonwealth Scholarship, and has received honors for his academic achievements. Additionally, his research publications in reputable journals underscore his growing influence in the scientific community.

Impact and Influence

Through his research, leadership roles, and volunteer activities, Jairus has made a significant impact on cancer education, awareness, and research in Kenya. His work has contributed to the understanding of cancer pathogenesis and has paved the way for innovative approaches to cancer management and treatment.

Legacy and Future Contributions

As Jairus continues his doctoral studies and pursues his research interests in cancer genetics, he aims to leave a lasting legacy in the field through groundbreaking discoveries and transformative contributions. His multidisciplinary approach, coupled with his passion for scientific inquiry, positions him as a promising leader in cancer research with the potential to drive positive change in the global fight against cancer.

Notable Publications

miR-4716–3p and the target AKT2 Gene/rs2304186 SNP are associated with blood cancer pathogenesis in Pakistani population 2024

In silico analysis of RPS4X (X-linked ribosomal protein) with active components from black seed (Nigella sativa) for potential treatment of multiple sclerosis 2024

Therapeutic capability of selected medicinal plants' bioactive constituents against the mutant ovarian TP53 gene; a computational approach 2023

Targeting allosteric sites on PDK-1 and PLK-1 with bioactive compounds from Daucus carota as a potential therapy for triple-negative breast cancer 2023

 

 

 

 

Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

National and Kapodistrian University of Athens | Greece

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Early Academic Pursuits

Andreas Agathangelidis initiated his scientific journey at Thessaloniki's "G. Papanikolaou" hospital, delving into Chronic Lymphocytic Leukemia (CLL) and antigens for his diploma thesis. Subsequently, his Ph.D. at Aristotle University focused on immunogenetics in B-cell malignancies.

Professional Endeavors

Agathangelidis conducted groundbreaking studies during his Ph.D., notably refining CLL molecular classification using a sizable patient cohort. His postdoctoral research at San Raffaele Scientific Institute, Milan, explored CLL and Monoclonal B lymphocytosis (MBL) under Professor Paolo Ghia, broadening his expertise in advanced genetic methodologies.

Contributions and Research Focus

Significant contributions include expansive studies on CLL patients and the largest worldwide series on Mantle Lymphoma (MCL), emphasizing the role of antigens in disease progression. He conducted diverse immunoprofiling studies, exploring gene rearrangements and subtyping based on immunogenetics, oncogenetics, and immunophenotype integration.

Accolades and Recognition

Agathangelidis' pioneering research secured recognition, including fellowships from the HFRI Foundation and industry funding from Gilead Sciences. His leadership in the "CLLon" project, studying the B cell receptor's role in CLL and MBL development, represents a significant achievement in cancer genetics.

Impact and Influence

His work has significantly challenged prevailing views in disease mechanisms, refining classifications, and paving the way for targeted therapies for B-cell malignancies. The extensive studies he led have had a substantial impact on understanding disease ontogeny and the development of potential treatments.

Legacy and Future Contributions

Currently an Assistant Professor at the National and Kapodistrian University of Athens, Agathangelidis continues his research using advanced NGS technologies. His focus on elucidating the B cell receptor's role in CLL and MBL development through deep sequencing and bioinformatics is poised to bring forth notable advancements in cancer genetics and potential therapeutic avenues.

Notable Publications

Recurrent mutations refine prognosis in chronic lymphocytic leukemia 2014 (219)

A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study 2015 (179)

Antigen receptor stereotypy in chronic lymphocytic leukemia 2016 (99)