Dr. Mamta Tripathi | Chemistry | Best Researcher Award

Swami Atmanand Government English Medium School | India

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Early Academic Pursuits

Dr. Mamta Tripathi's journey in academia began with a strong foundation in the sciences. She earned her Bachelor of Science (B.Sc.) degree in Chemistry, Botany, and Biotechnology from G.D. Rungta College of Science & Technology, Bhilai, achieving a notable 70.88% in 2010. Her academic excellence continued with a Master of Science (M.Sc.) in Chemistry from Pt. Ravishankar Shukla University, Raipur, where she graduated with a gold medal in 2012, scoring 74.38%. Dr. Tripathi's passion for research was evident early on, leading her to pursue a Ph.D. in Chemistry at the same university, focusing on the study of Hydroxamic Acid-Metal complexes and their biological properties, which she completed in 2018 under the mentorship of Prof. Rama Pande.

Professional Endeavors

Dr. Tripathi's professional career is marked by a blend of teaching and research roles. From 2013 to 2018, she was an active INSPIRE Research Scholar at Pt. Ravishankar Shukla University, where she worked on her doctoral degree while also engaging in teaching. Following her doctoral studies, she served as a guest lecturer at the same university from 2019 to 2020. Currently, she is a Postgraduate Teacher (PGT) in Chemistry at D.A.V. ISPAT School, Bhilai. In addition to her teaching roles, she has also served as a C.B.S.E. observer in two schools, highlighting her commitment to educational excellence.

Contributions and Research Focus

Dr. Tripathi's research is primarily centered around Chemical Biology, with a particular focus on the interaction of Hydroxamic Acid-Metal complexes with nucleic acids and enzymes. Her thesis, titled “Studies on Hydroxamic Acid Metal Complexes as Nucleic Acid Binder and Enzymatic Inhibitors,” involved pioneering studies on the binding properties of these complexes using various spectroscopic and computational techniques. Her work demonstrated significant findings, such as the minor and major groove binding modes of these complexes with DNA/RNA and their inhibitory effects on enzymes like HDAC 8. Furthermore, she explored the cytotoxicity of these complexes against breast cancer cells, contributing valuable insights to the field of chemical biology and potential therapeutic applications.

Accolades and Recognition

Dr. Tripathi's contributions to science have been recognized through several awards and honors. She was an INSPIRE Fellow, receiving financial assistance from the Department of Science & Technology, New Delhi. She topped the M.Sc. merit list in 2012, earning four gold medals in 2013. Her outstanding research has also earned her the National Young Scientist Award from the Indian Council of Chemists in 2016 and the State Young Scientist Award at the Chhattisgarh Young Scientist Awards in 2017. These accolades reflect her dedication and impact in her field.

Impact and Influence

Dr. Tripathi has made significant contributions to the scientific community through her research publications and conference presentations. She has co-authored numerous research papers published in prestigious journals, covering topics such as DNA binding studies, molecular docking, and the cytotoxicity of metal complexes. Her work has provided valuable insights into the interaction of metal complexes with biological molecules, potentially influencing future research and therapeutic developments.

Legacy and Future Contributions

Dr. Tripathi's legacy in the field of chemical biology is marked by her innovative research and dedication to education. Her findings on Hydroxamic Acid-Metal complexes have paved the way for further studies in nucleic acid binding and enzyme inhibition. As she continues her career, Dr. Tripathi aims to expand her research into new areas and contribute to the development of novel therapeutic agents. Her commitment to education ensures that she will continue to inspire and mentor future generations of scientists.

Notable Publications

In-vitro and in-silico analysis and antitumor studies of novel Cu(II) and V(V) complexes of N-p-Tolylbenzohydroxamic acid 2024

Copper(ii) complexes supported by modified azo-based ligands: Nucleic acid binding and molecular docking studies 2022 (1)

N-hydroxypyrazine-2-carboxamide as a new and green corrosion inhibitor for mild steel in acidic medium: experimental, surface morphological and theoretical approach 2022 (16)

In‐vitro investigation of biophysical interactions between Ag(I) complexes of bis (methyl)(thia/selena) salen and ct‐DNA via multi‐spectroscopic, physicochemical and molecular docking methods along with cytotoxicity study 2021 (3)

Spatiotemporal variability and source apportionment of the ionic components of groundwater of a mineral-rich tribal belt in Bastar, India 2020 (21)