Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof. Hyun Min Kim | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Duke Kunshan University | China

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🎓 Early Academic Pursuits

Prof. Hyun Min Kim's journey in the scientific realm began with a Bachelor of Science in Life Science from Hanyang University, Seoul, South Korea, in 1997. This foundational phase nurtured his interest in microbiology, leading to a Master of Science in Life Science (Microbiology) from the same institution in 1999. His academic ascent culminated in a Ph.D. in Applied Biology (Genetics and Molecular Cell Biology) at Georgia Institute of Technology, USA, in 2009, where he explored genome instability, tri-nucleotide repeats, and their genetic implications. This solid academic grounding propelled him toward groundbreaking discoveries.

👨‍🔬 Professional Endeavors

Prof. Kim’s illustrious career spans continents and decades, beginning as a Chief Research Scientist at Hanyang University Medical School, focusing on cytokine profiling and toll-like receptor proteins. His time as a Research Assistant and later a Post-doctoral Fellow at Harvard Medical School cemented his expertise in genome editing and DNA damage repair mechanisms.
His roles as Associate Professor at Tianjin University and Duke Kunshan University underscore his contributions to epigenetics and the development of CRISPR-Cas9 systems. Currently, he serves as an Associate Professor of the Practice at Duke University, advancing molecular biology through cutting-edge research on histone demethylases and DNA damage repair.

🔬 Contributions and Research Focus

Prof. Kim's research revolves around epigenetic regulation and genome editing. He has made pivotal contributions to understanding histone demethylases' roles in DNA damage repair and cancer pathways. His work on CRISPR-Cas9 has refined genome editing techniques, particularly in C. elegans, enabling advances in genetic and therapeutic research. His publications, spanning high-impact journals like Biomolecules, Frontiers in Genetics, and Nature Communications, highlight his dedication to elucidating molecular mechanisms influencing genetic stability and cancer development.

🏆 Accolades and Recognition

Prof. Kim's academic excellence has been consistently recognized. From early scholarships at Hanyang University to the prestigious Sarstedt® Graduate Student Award for his Ph.D. accomplishments, his journey is marked by accolades. He received the Faculty Teaching Award at Tianjin University and multiple travel and mentorship awards, showcasing his dual strengths as a researcher and educator. His innovative work has also attracted significant funding, including grants from the National Natural Science Foundation of China and the Kunshan Shuangchuang Grant, totaling millions in support for his transformative projects.

🌟 Impact and Influence

Prof. Kim's efforts have shaped the scientific and academic communities. His leadership roles, such as organizing journal clubs at Harvard Medical School and contributing to editorial boards like Life Journal and Jove Journal, underscore his influence. As a mentor, he has guided budding researchers and students, exemplified by his award for mentoring undergraduates at Georgia Tech. His findings in genome stability, CRISPR-Cas9, and epigenetics continue to inspire advancements in genetic engineering and cancer therapy.

✨ Legacy and Future Contributions

With an eye on the future, Prof. Kim remains committed to unraveling the mysteries of molecular genetics and epigenetics. His work lays a foundation for next-generation cancer therapeutics and genome editing platforms. As a leader in both teaching and research, his legacy will undoubtedly endure, fostering innovation and collaboration in life sciences globally.

 

Publications


📄 Torenia sp. Extracts Contain Multiple Potent Antitumor Compounds with Nematocidal Activity, Triggering an Activated DNA Damage Checkpoint and Defective Meiotic Progression

  • Author: Meng, Q., Borris, R.P., Kim, H.-M.
  • Journal: Pharmaceuticals
  • Year: 2024

📄 Exploring the Impact of Onobrychis cornuta and Veratrum lobelianum Extracts on C. elegans: Implications for MAPK Modulation, Germline Development, and Antitumor Properties

  • Author: Meng, Q., Pathak, N., Ren, X., Borris, R.P., Kim, H.-M.
  • Journal: Nutrients
  • Year: 2024

📖 LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond

  • Author: Kim, H.-M., Liu, Z.
  • Journal: Biomolecules
  • Year: 2024

📖 Experimental Insights into the Interplay between Histone Modifiers and p53 in Regulating Gene Expression

  • Author: Kim, H.-M., Zheng, X., Lee, E.
  • Journal: International Journal of Molecular Sciences,
  • Year:  2023

📖 A Decade of CRISPR-Cas Genome Editing in C. elegans

  • Author: Kim, H.-M., Hong, Y., Chen, J.
  • Journal:  International Journal of Molecular Sciences
  • Year:  2022

 

Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Assist Prof  Dr. Andreas Agathangelidis | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

National and Kapodistrian University of Athens | Greece

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Early Academic Pursuits

Andreas Agathangelidis initiated his scientific journey at Thessaloniki's "G. Papanikolaou" hospital, delving into Chronic Lymphocytic Leukemia (CLL) and antigens for his diploma thesis. Subsequently, his Ph.D. at Aristotle University focused on immunogenetics in B-cell malignancies.

Professional Endeavors

Agathangelidis conducted groundbreaking studies during his Ph.D., notably refining CLL molecular classification using a sizable patient cohort. His postdoctoral research at San Raffaele Scientific Institute, Milan, explored CLL and Monoclonal B lymphocytosis (MBL) under Professor Paolo Ghia, broadening his expertise in advanced genetic methodologies.

Contributions and Research Focus

Significant contributions include expansive studies on CLL patients and the largest worldwide series on Mantle Lymphoma (MCL), emphasizing the role of antigens in disease progression. He conducted diverse immunoprofiling studies, exploring gene rearrangements and subtyping based on immunogenetics, oncogenetics, and immunophenotype integration.

Accolades and Recognition

Agathangelidis' pioneering research secured recognition, including fellowships from the HFRI Foundation and industry funding from Gilead Sciences. His leadership in the "CLLon" project, studying the B cell receptor's role in CLL and MBL development, represents a significant achievement in cancer genetics.

Impact and Influence

His work has significantly challenged prevailing views in disease mechanisms, refining classifications, and paving the way for targeted therapies for B-cell malignancies. The extensive studies he led have had a substantial impact on understanding disease ontogeny and the development of potential treatments.

Legacy and Future Contributions

Currently an Assistant Professor at the National and Kapodistrian University of Athens, Agathangelidis continues his research using advanced NGS technologies. His focus on elucidating the B cell receptor's role in CLL and MBL development through deep sequencing and bioinformatics is poised to bring forth notable advancements in cancer genetics and potential therapeutic avenues.

Notable Publications

Recurrent mutations refine prognosis in chronic lymphocytic leukemia 2014 (219)

A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study 2015 (179)

Antigen receptor stereotypy in chronic lymphocytic leukemia 2016 (99)