University of Fribourg | Switzerland
Mrs. Sophie Grigolo is an emerging researcher specializing in cellular and molecular biology, with a strong focus on cancer research, particularly clear-cell renal-cell carcinoma (ccRCC). Her work encompasses extensive laboratory expertise in cell culture using human kidney cancer cell lines (A-498, ACHN, Caki-1, and Caki-2) and a range of analytical assays including BrdU Cell Proliferation, MTT, LDH, and Live-or-Dye™ Fixable Viability Staining. She is proficient in advanced molecular biology techniques such as polymerase chain reaction (PCR), agarose gel electrophoresis, western blotting, genotyping, flow cytometry, and immunohistochemistry (IHC), which she applies to elucidate cancer cell behavior and therapeutic responses. Her publications, including studies on immunotherapy in ccRCC and the role of IL-2 receptor expression in renal carcinoma cells, contribute to advancing understanding of tumor immunology and targeted therapies. Sophie has also shared her findings at prestigious scientific forums, including the International Student Congress of (bio)Medical Sciences and the Annual European Student Symposium on Anatomical Research, where her work has earned recognition for excellence. Through her research and technical acumen, she continues to contribute to the evolving field of cancer biology and the development of innovative therapeutic approaches.
Profile : Orcid
Featured Publications
Grigolo, S., Fellay, I., & Filgueira, L. (2025). IL-2 receptor expression in renal cell carcinoma cells: IL-2 influences cell survival and induces cell death. Current Issues in Molecular Biology, 47(10), 830.
Grigolo, S., & Filgueira, L. (2024). Immunotherapy of clear-cell renal-cell carcinoma. Cancers, 16, 2092.