Zhuowei Luo | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Mr. Zhuowei Luo | Pharmacology, Toxicology and Pharmaceutical Science | Research Excellence Award

Hubei University of Chinese Medicine | China

Mr. Zhuowei Luo is an emerging researcher recognized for effectively integrating classical Traditional Chinese Medicine (TCM) theory with modern biomedical science, demonstrating strong expertise in molecular mechanism analysis and advanced metabolomics for chronic disease research. His notable scientific contribution is a co-authored publication in the Journal of Ethnopharmacology (Q2, IF 5.14), where he helped elucidate how Allium macrostemon delays chronic renal failure by modulating the IL-17 signaling pathway and altering tryptophan and glycerophospholipid metabolism. This work represents the first comprehensive study connecting immunological regulation with multi-omics profiling to explain the therapeutic mechanisms of this TCM herb, providing a meaningful model for modernizing traditional medicine through systems biology. His role in the project included designing and validating qPCR primers, conducting network pharmacology to identify key molecular targets, performing metabolomics and transcriptomics data analyses, and carrying out histopathological assessments. Through these contributions, he demonstrated an advanced ability to apply interdisciplinary approaches—combining immunology, pharmacology, and bioinformatics—to uncover mechanistic insights into natural product–based interventions. His research reflects scientific maturity beyond typical early-stage experience and contributes to the growing evidence supporting data-driven modernization of TCM in chronic disease treatment.

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Featured Publication

Zhao, Y., Ge, J. X., Zhang, N., Lei, Z. X., Sun, S. Y., Luo, Z. W., Yang, Y. F., & Wu, H. Z. (2025). Allium macrostemon Bge. delays chronic renal failure by modulating IL-17 signaling pathway and affecting tryptophan/glycerophospholipid metabolism. Journal of Ethnopharmacology, 120946.