Rengui Saxu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Dr. Rengui Saxu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

China Pharmaceutical University | China                    

Author Profile

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Early Academic Pursuits ๐ŸŽ“

Dr. Rengui Saxu began his academic journey at Shenyang Medical College, where he pursued a degree in Clinical Medicine Science from 2012 to 2017. During his studies, he completed an internship at Shenyang Central Hospital in 2017, gaining hands-on experience in clinical practice. His academic dedication earned him the National Encouragement Scholarship and the title of Outstanding Graduate, marking his potential as a rising scholar in the field of medicine. Continuing his academic path, Dr. Saxu pursued a Master of Pharmacy Engineering at Tianjin University of Science & Technology from 2017 to 2020. During this time, he took on leadership roles, notably serving as the Head of the Academic Department of the University Graduate Association. His work in pharmacy engineering was recognized with the Zhixing Scholarship for Postgraduate Students.

Professional Endeavors ๐Ÿ…

Dr. Saxu is currently engaged in advanced research as a Ph.D. candidate in Pharmacology at China Pharmaceutical University (2021-2025). He works under the supervision of Yong Yang, a prominent figure in pharmacological research, and Harvest F. Gu, Chief Scientist at Karolinska Medical School in Sweden. His research spans crucial areas in pharmacology, focusing on drug development and the mechanisms of disease, particularly in relation to diabetes, kidney disease, and cancer.

Contributions and Research Focus ๐Ÿ”ฌ

Dr. Saxu's research contributions are vast, with a focus on pharmacological innovations and therapeutic interventions for diseases like diabetes and cancer. One of his notable patents is a Chinese patent for a method involving selenium-substituted axitinib, which offers anti-tumor applications. His academic publications reflect his deep involvement in cutting-edge research:

  • His studies on asymmetries in adrenal glands and their role in glucocorticoid production provide insights into diabetes-related obesity.
  • He has explored the therapeutic potential of Abelmoschus manihot (L.) in treating diabetic nephropathy via the gut-kidney axis, contributing to the advancement of herbal medicine in disease management.
  • Dr. Saxu has also investigated how Huangkui capsules inhibit aldosterone synthesis in diabetic kidney disease, a promising direction for traditional Chinese medicine.

Accolades and Recognition ๐Ÿ†

Dr. Saxu's academic excellence has been recognized through numerous prestigious awards:

  • National Encouragement Scholarship
  • Zhixing Scholarship for Postgraduate Students
  • Doctoral Research Incentive Scholarship
  • Outstanding Doctoral Scholarship

These accolades reflect his commitment to research and innovation in the field of pharmacology.

Impact and Influence ๐ŸŒ

Dr. Saxu's research has had a considerable impact on the medical and pharmacological fields, particularly in the treatment of diabetes and kidney disease. His work on drug therapy and natural compound-based treatments has opened new avenues for understanding and combating complex diseases. His research not only influences medical practices in China but also has international implications, especially in areas related to drug efficacy and safety.

Legacy and Future Contributions ๐Ÿš€

Dr. Saxuโ€™s future contributions are poised to advance pharmacological research significantly, especially in the areas of cancer therapy and chronic disease management. As a researcher under highly esteemed mentors like Yong Yang and Harvest F. Gu, his ongoing work will likely lead to breakthroughs in targeted therapies and personalized medicine. In the years to come, Dr. Saxu's work will continue to shape the landscape of pharmaceutical sciences, offering hope for more effective and less harmful treatment options. His contributions to medical research, especially in oncology and diabetes, will leave a lasting legacy in global healthcare.

 

Publications


๐Ÿ“œ Higher Steroid Production in the Right Adrenal Gland Compared to the Left One in db/db Mice, a Model of Type 2 Diabetic Obesity

  • Authors: Rengui Saxu, Qiming Luo, Yong Yang, Harvest F. Gu
  • Journal: International Journal of Molecular Sciences
  • Year: 2024

๐Ÿ“œ Asymmetries of Left and Right Adrenal Glands in Neural Innervation and Glucocorticoids Production

  • Authors: Rengui Saxu, Yong Yang, Harvest F. Gu
  • Journal: International Journal of Molecular Sciences
  • Year: 2023

 

Jialu Xu | Neuroscience | Best Researcher Award

Dr. Jialu Xu | Neuroscience | Best Researcher Award

Huazhong University of Science and Technology | China

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Early Academic Pursuits ๐ŸŽ“

Dr. Jialu Xu has shown remarkable dedication to scientific research from early on in his academic journey. Having pursued a strong foundation in biomedical sciences, his commitment to understanding complex biological mechanisms has been evident through his involvement in various academic projects. His educational background at Huazhong University of Science and Technology laid the groundwork for his focus on biomedical research, particularly in the study of cognitive impairment and its underlying causes.

Professional Endeavors ๐Ÿ’ผ

Dr. Xu is currently affiliated with Huazhong University of Science and Technology, where he actively contributes to research at Tongji Hospital. His work is interdisciplinary, spanning both clinical and laboratory settings. Dr. Xu's professional role has been instrumental in investigating the intricate pathways involved in cognitive diseases, where he collaborates with colleagues on cutting-edge research projects aimed at improving patient care and advancing scientific knowledge.

Contributions and Research Focus ๐Ÿ”ฌ

One of Dr. Xu's most significant contributions is his study on how high-carbohydrate diets can lead to cognitive impairment. His research, published in Biomedicines in July 2024, demonstrates how these diets promote amyloid burden and tau phosphorylation through the PI3K/Akt/GSK-3ฮฒ pathway in db/db mice. This groundbreaking work provides insights into the molecular mechanisms underlying neurodegenerative diseases like Alzheimerโ€™s, opening doors to potential new therapeutic interventions. His research interests encompass neurology, metabolic disorders, and molecular pathways related to brain health.

Accolades and Recognition ๐Ÿ†

Dr. Xuโ€™s innovative research has garnered recognition in the scientific community. His recent publication in Biomedicines has been well-received, highlighting his growing reputation as a leader in cognitive impairment research. His work has contributed to expanding the knowledge base around neurodegenerative disorders and is recognized for its potential impact on future treatments.

Impact and Influence ๐ŸŒ

Dr. Xuโ€™s research not only influences the academic community but also has far-reaching implications for public health, especially in areas related to diet and neurodegenerative diseases. His findings on the impact of high-carbohydrate diets on cognitive health offer valuable guidance for clinicians and dieticians in developing preventive strategies and interventions for at-risk populations.

Legacy and Future Contributions ๐ŸŒŸ

As Dr. Xu continues to expand his research, his future contributions are poised to significantly advance the understanding of cognitive diseases. His ongoing work will likely explore more innovative solutions to mitigate the effects of poor dietary habits on brain health. Dr. Xuโ€™s legacy will be one of pioneering research that bridges the gap between molecular biology and practical health outcomes, ensuring his work leaves a lasting mark on the fields of neurology and dietary science.

 

Publications


๐Ÿ“ A High-Carbohydrate Diet Induces Cognitive Impairment and Promotes Amyloid Burden and Tau Phosphorylation via PI3K/Akt/GSK-3ฮฒ Pathway in db/db Mice
Author: Jialu Xu; Lei Xie; Jiaxin Yin; Xiaoli Shi; Kun Dong; Jing Tao; Weijie Xu; Delin Ma; Shujun Zhang; Juan Chen et al.
Journal: Biomedicines
Year: 2024


 

Vijayalakshmi Venkatesan | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Dr. Vijayalakshmi Venkatesan | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Regenerative Research Sciences Private Limited | India

Author profile

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Early Academic Pursuits

Dr. Vijayalakshmi Venkatesan began her academic journey with a B.Sc. in Botany, Zoology, and Chemistry, achieving First Class with Distinction. She pursued her passion further with an M.Sc. in Biochemistry, securing the second rank in the university. Her academic pursuit culminated in a Ph.D. in Biochemistry from the National Institute of Nutrition/Osmania University. Following this, she engaged in postdoctoral research at the Centre for Cellular and Molecular Biology.

Professional Endeavors

Dr. Vijayalakshmi Venkatesan's professional journey has been marked by significant roles in academia and research. She served as the Director-Grade Scientist and Head of Cell & Molecular Biology and Stem Cell Research at the National Institute of Nutrition, ICMR, Hyderabad. Currently, she holds the position of Director-Research at Movva Health Care LLP, RegenOrthoSport, where she continues to contribute to cutting-edge research in biochemistry and stem cell research.

Contributions and Research Focus

Her research focuses on regenerative medicine, particularly in addressing non-communicable diseases (NCDs) like diabetes, obesity, and knee osteoarthritis. Dr. Vijayalakshmi Venkatesan's work involves understanding the pathophysiology of these diseases at the cellular and molecular levels. She has made significant strides in the isolation, characterization, and therapeutic application of mesenchymal stem cells (MSCs) derived from various sources, including placenta and bone marrow. Additionally, her research explores the potential of nutraceuticals in managing these conditions, highlighting the beneficial effects of compounds like stigmasterol, gingerol, and shogaol.

Accolades and Recognition

Dr. Vijayalakshmi Venkatesan's contributions to the field have been recognized through numerous awards and honors. She has been felicitated with awards such as the Woman of Excellence Award, Venus International Award for Excellence in Biochemistry and Stem Cell Research, and the Dr. S.N. Acharya Felicitation Award. Her expertise has also earned her fellowship status in prestigious organizations like the National Academy of Medical Sciences and the Telangana Academy of Sciences.

Impact and Influence

Dr. Vijayalakshmi Venkatesan's research has left a significant impact on both academia and clinical practice. Her findings have been published extensively in peer-reviewed journals, with over 100 scientific articles and several book chapters to her credit. She has also been granted multiple patents for her innovative research in liver cell therapy and mesenchymal stem cell transplantation. Moreover, she actively participates in various professional societies and serves on the editorial boards of esteemed journals in the field.

Legacy and Future Contributions

Dr. Vijayalakshmi Venkatesan's legacy lies in her pioneering work at the intersection of biochemistry, genetics, and regenerative medicine. Her ongoing efforts in translational research aim to bridge the gap between laboratory discoveries and clinical applications, with a focus on improving healthcare outcomes for patients with metabolic disorders and musculoskeletal conditions. As she continues to lead research initiatives and mentor future scientists, her contributions are poised to shape the future of regenerative medicine and personalized healthcare.

Notable Publications

Alleviation of diabetes mellitus through the restoration of ฮฒ-cell function and lipid metabolism by Aloe vera (L.) Burm. f. extract in obesogenic WNIN/GR-Ob rats  2021 (19)

Elevated ATP, cytokines and potential microglial inflammation distinguish exfoliation glaucoma from exfoliation syndrome 2022 (7)

The role of Lp-PLA2 and biochemistry parameters as potential biomarkers of coronary artery disease in Asian South-Indians: a case-control study 2017 (10)