School of Medicine,Xiamen University | China
Author Profile
Scopus
📘 Early Academic Pursuits
Mr. Shuai Wang's academic journey began with a strong foundation in Biological Sciences, earning his Bachelor’s degree from Yantai University (2014–2018). He then pursued a Master’s degree in Biology (2018–2019) and a PhD in Cell Biology (2019–2023) from Xiamen University, one of China's top research institutions. This rapid academic progression reflects his commitment to understanding complex biological systems, particularly in disease mechanisms and cellular functions.
💼 Professional Endeavors
Since September 2023, Mr. Wang has served as an Assistant Researcher at the School of Medicine, First Affiliated Hospital of Xiamen University. His work spans academic and translational research in molecular biology and metabolic disorders, with an emphasis on mechanisms of thermogenesis, obesity, and chemotherapy resistance in liver cancer. Prior to this role, he gained substantial laboratory experience during his doctoral training, shaping his precision and insight in experimental design and scientific interpretation.
🔬 Contributions and Research Focus
Mr. Wang's primary research contributions revolve around metabolic regulation, adipocyte biology, and molecular signaling pathways. He has a special interest in how transcription factors like SOX4 influence the development and function of brown and beige adipose tissue, crucial for thermogenesis and metabolic health. His recent involvement in National Natural Science Foundation-funded research explores the role of DNA demethylase TET1 in chemoresistance in liver cancer—a timely and impactful topic in cancer therapy.
🏆 Accolades and Recognition
Mr. Wang has authored several high-impact publications in prestigious journals, including:
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Cell Death and Differentiation (2024) – as sole first author, on SOX4 and brown fat development
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Journal of Cardiovascular Medicine and Cardiology (2024) – sole first author, linking obesity to cardiovascular diseases
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iScience (2023) and Theranostics (2022) – as co-first author, detailing SOX4’s role in white adipose tissue and adaptive thermogenesis
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Food Chemistry (2025) – as co-corresponding author, exploring antioxidant mechanisms via computational chemistry
These publications establish his reputation as a rising researcher with both depth and interdisciplinary reach.
🌍 Impact and Influence
Through his pioneering research in thermogenic gene regulation and molecular metabolism, Mr. Wang contributes directly to the fields of metabolic disease, obesity treatment, and precision oncology. His research not only enhances our understanding of adipocyte biology but also opens doors to innovative therapies for chronic diseases and cancer.
🧭 Legacy and Future Contributions
With a promising start as an independent researcher and a growing portfolio of impactful publications, Mr. Shuai Wang is poised to become a leading figure in biomedical research. His future work is expected to deepen the mechanistic understanding of metabolic health and cancer resistance, while inspiring collaborations across disciplines like biomedicine, pharmacology, and computational biology.
Publications
📝 Synergistic effects of polymethoxyflavonoids from citrus peel extracts on harmful compound formation and flavor quality in grilled beef patties
📝 SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice
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Authors: Shuai Wang, Ting He, Ya Luo, Kexin Ren, Huanming Shen, Lingfeng Hou, Yixin Wei, Tong Fu, Wenlong Xie, Peng Wang, Jie Hu, Yu Zhu, Zhengrong Huang, Qiyuan Li, Weihua Li, Huiling Guo, Boan Li
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Journal: Cell Death and Differentiation
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Year: 2024
📝 Obesity: A Key Causative Factor in Cardiovascular Disease Development
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Authors: Shuai Wang, Ting He, Chunli Mo, Kangfeng Lin, Cui Yang, Weihua Li
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Journal: Journal of Cardiovascular Medicine and Cardiology
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Year: 2024
📝 Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity
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Authors: Ting He, Shuai Wang, Shengnan Li, Huanming Shen, Lingfeng Hou, Yunjia Liu, Yixin Wei, Fuan Xie, Zhiming Zhang, Zehang Zhao, Chunli Mo, Huiling Guo, Qingsong Huang, Rui Zhang, Dongyan Shen, Boan Li
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Journal: iScience
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Year: 2023
📝 SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex
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Authors: Huanming Shen, Ting He, Shuai Wang, Lingfeng Hou, Yixin Wei, Yunjia Liu, Chunli Mo, Zehang Zhao, Weixin You, Huiling Guo, Boan Li
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Journal: Theranostics
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Year: 2022
📝 Augmenting antioxidative capacity of myosin and cytoprotective potential of myosin digestion products through the integration of crocin and crocetin: A comprehensive analysis via quantum chemical computing and molecular dynamics
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Authors: Chaoyi Xue, Jian Zhang, Chenxia Zhang, Zhonghao Hu, Huixue Liu, Lan Mo, Maiquan Li, Aihua Lou, Qingwu Shen, Jie Luo, Shuai Wang, Wei Quan
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Journal: Food Chemistry
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Year: 2025